GSK-3 and BCL-XL inhibition mitigates the competitive advantage of APC-mutant colorectal cancer c...

GSK-3 and BCL-XL inhibition mitigates the competitive advantage of APC-mutant colorectal cancer cells  Nature

Ascentage Pharma Announces Its Novel Bcl-2 Inhibitor - GlobeNewswire

Ascentage Pharma Announces Its Novel Bcl-2 Inhibitor  GlobeNewswire

Samokov set to host BCL Qualification Round Tournaments - Basketball Champions League

Samokov set to host BCL Qualification Round Tournaments  Basketball Champions League

Ryan Arcidiacono replaces Justin Robinson at Trapani, heading to the BCL - Eurohoops

Ryan Arcidiacono replaces Justin Robinson at Trapani, heading to the BCL  Eurohoops

ESB-MACC: Homebuyers Workshop with BCL of Texas - AustinTexas.gov

ESB-MACC: Homebuyers Workshop with BCL of Texas  AustinTexas.gov

Discovery of XZ338, a highly potent BCL-XL degrader - ScienceDirect.com

Discovery of XZ338, a highly potent BCL-XL degrader  ScienceDirect.com

Meet the BCL Asia 2025 teams: Changwon LG Sakers - fiba.basketball

Meet the BCL Asia 2025 teams: Changwon LG Sakers  fiba.basketball

The BCL-2 protein family: from discovery to drug development - Cell Death & Differentiation - Nature

The BCL-2 protein family: from discovery to drug development - Cell Death & Differentiation  Nature

Basketball Champions League Season 10 lineup announced - Basketball Champions League

Basketball Champions League Season 10 lineup announced  Basketball Champions League

The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilte...

The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN–GIL hybrid single-molecule inhibitors  ScienceDirect.com

Pairings, schedule confirmed for BCL Asia 2025 Quarter-Finals - fiba.basketball

Pairings, schedule confirmed for BCL Asia 2025 Quarter-Finals  fiba.basketball

BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress ...

BH3 mimetics targeting BCL-XL have efficacy in solid tumors with RB1 loss and replication stress  Nature

Discovery of XZ338, a highly potent BCL-XL degrader - ScienceDirect.com

Discovery of XZ338, a highly potent BCL-XL degrader  ScienceDirect.com

Proapoptotic Bcl-2 inhibitor as potential host directed therapy for pulmonary tuberculosis - Nature

Proapoptotic Bcl-2 inhibitor as potential host directed therapy for pulmonary tuberculosis  Nature

Polypeptide nanomicelles co-deliver PLK1 and BCL-2/xL inhibitors for synergetic therapy of brain ...

Polypeptide nanomicelles co-deliver PLK1 and BCL-2/xL inhibitors for synergetic therapy of brain tumor  ScienceDirect.com

Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearran...

Novel selective strategies targeting the BCL-2 family to enhance clinical efficacy in ALK-rearranged non-small cell lung cancer | Cell Death & Disease  Nature

A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hep...

A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice  Nature

Subtype-specific prognostic impact of Bcl-2 in HER2-positive and HER2-negative breast cancer - Na...

Subtype-specific prognostic impact of Bcl-2 in HER2-positive and HER2-negative breast cancer  Nature

HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-ind...

HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells  Nature

Dimethyl fumarate abrogates hepatocellular carcinoma growth by inhibiting Nrf2/Bcl-xL axis and en...

Dimethyl fumarate abrogates hepatocellular carcinoma growth by inhibiting Nrf2/Bcl-xL axis and enhances sorafenib’s efficacy  Nature

FAN VOTE: Who is the best player in BCL Asia 2025? - fiba.basketball

FAN VOTE: Who is the best player in BCL Asia 2025?  fiba.basketball

Plant BCL-DOMAIN HOMOLOG proteins play a conserved role in SWI/SNF complex stability - PNAS

Plant BCL-DOMAIN HOMOLOG proteins play a conserved role in SWI/SNF complex stability  PNAS

BCL-XL–targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechan...

BCL-XL–targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechanism toxicity of small-molecule inhibitors  Science | AAAS

Meralco in the BCL Asia: Can the Bolts endure the tough load and deliver? - ESPN

Meralco in the BCL Asia: Can the Bolts endure the tough load and deliver?  ESPN

Full BCL Asia 2025 schedule all set - fiba.basketball

Full BCL Asia 2025 schedule all set  fiba.basketball

Meet the BCL Asia 2025 teams: Broncos - fiba.basketball

Meet the BCL Asia 2025 teams: Broncos  fiba.basketball

Groupings for BCL Asia 2025 confirmed - fiba.basketball

Groupings for BCL Asia 2025 confirmed  fiba.basketball

Dual-Functional Hafnium Oxide Nanoplatform Combining High-Z Radiosensitization With Bcl-2 Gene Si...

Dual-Functional Hafnium Oxide Nanoplatform Combining High-Z Radiosensitization With Bcl-2 Gene Silencing for Enhanced Cancer Radiotherapy  Wiley

Expression of BCL-2 and Laminin in Rectosigmoid Hirschsprung Disease: Correlations with Hirschspr...

Expression of BCL-2 and Laminin in Rectosigmoid Hirschsprung Disease: Correlations with Hirschsprung−Associated Enterocolitis  Nature

Meet the BCL Asia 2025 teams: Al Riyadi - fiba.basketball

Meet the BCL Asia 2025 teams: Al Riyadi  fiba.basketball

Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3 | Cell Death & D...

Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3 | Cell Death & Disease  Nature

Schedule of games announced for BCL Asia-East - fiba.basketball

Schedule of games announced for BCL Asia-East  fiba.basketball

BCL Asia 2025 set to ignite unique fan frenzy in Dubai - fiba.basketball

BCL Asia 2025 set to ignite unique fan frenzy in Dubai  fiba.basketball

Crvena Zvezda officially announces arrival of BCL champion - BasketNews.com

Crvena Zvezda officially announces arrival of BCL champion  BasketNews.com

Games Schedule & Results - BCL Asia - East 2025 - fiba.basketball

Games Schedule & Results - BCL Asia - East 2025  fiba.basketball

Al Riyadi, Tabiat qualify for BCL Asia 2025 - fiba.basketball

Al Riyadi, Tabiat qualify for BCL Asia 2025  fiba.basketball

New-look BCL Asia-East to tip off in March - fiba.basketball

New-look BCL Asia-East to tip off in March  fiba.basketball

Mongolia to host BCL Asia-East 2025 Final 4 - fiba.basketball

Mongolia to host BCL Asia-East 2025 Final 4  fiba.basketball

The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium relea...

The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium release  Nature

Dubai to host BCL Asia 2025 - fiba.basketball

Dubai to host BCL Asia 2025  fiba.basketball

Five takeaways from the BCL Asia-East 2025 Group Phase - fiba.basketball

Five takeaways from the BCL Asia-East 2025 Group Phase  fiba.basketball

Bcl-x short-isoform is essential for maintaining homeostasis of multiple tissues - ScienceDirect.com

Bcl-x short-isoform is essential for maintaining homeostasis of multiple tissues  ScienceDirect.com

Discovery and development of thiazolidine-2,4-dione derivatives as Bcl-2/Mcl-1 dual inhibitors - ...

Discovery and development of thiazolidine-2,4-dione derivatives as Bcl-2/Mcl-1 dual inhibitors  ScienceDirect.com

The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis s...

The BCL-2 family protein BCL-RAMBO interacts and cooperates with GRP75 to promote its apoptosis signaling pathway  Nature

BCL-XL regulates the timing of mitotic apoptosis independently of BCL2 and MCL1 compensation - Na...

BCL-XL regulates the timing of mitotic apoptosis independently of BCL2 and MCL1 compensation  Nature

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19 - ScienceDire...

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19  ScienceDirect.com

BCL-w: apoptotic and non-apoptotic role in health and disease - Nature

BCL-w: apoptotic and non-apoptotic role in health and disease  Nature

Bcl-XL: A multifunctional anti-apoptotic protein - ScienceDirect.com

Bcl-XL: A multifunctional anti-apoptotic protein  ScienceDirect.com

Bureau of Clinical Laboratories - Alabama Department of Public Health (.gov)

Bureau of Clinical Laboratories  Alabama Department of Public Health (.gov)

Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and th...

Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and this effect is limited by cancer-associated fibroblasts  Nature

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity, - Nature

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,  Nature

Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity - Nature

Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity  Nature

Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X - Nature

Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X  Nature

DNAi-peptide nanohybrid smart particles target BCL-2 oncogene and induce apoptosis in breast canc...

DNAi-peptide nanohybrid smart particles target BCL-2 oncogene and induce apoptosis in breast cancer cells  ScienceDirect.com

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells | Nat...

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells | Nature Communications  Nature

Bcl-2 family inhibitors sensitize human cancer models to therapy - Cell Death & Disease - Nature

Bcl-2 family inhibitors sensitize human cancer models to therapy - Cell Death & Disease  Nature

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoti...

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation  Nature

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer - Nature

Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer  Nature

A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity | Nature Medicine ...

A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity | Nature Medicine  Nature

Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL...

Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL  Nature

Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gas...

Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency  Molecular Cancer

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis - Nature

Mechanisms of BCL-2 family proteins in mitochondrial apoptosis  Nature

Correlation of Bcl-2 expression with prognosis and survival in patients with head and neck cancer...

Correlation of Bcl-2 expression with prognosis and survival in patients with head and neck cancer: A systematic review and meta-analysis  ScienceDirect.com

Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis | Cell D...

Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis | Cell Death & Differentiation  Nature

inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF - Nature

inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF  Nature

Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance - Nature

Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance  Nature

The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that med...

The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance  Nature

T cells with high BCL-2 expression induced by venetoclax impact anti-leukemic immunity “graft-ver...

T cells with high BCL-2 expression induced by venetoclax impact anti-leukemic immunity “graft-versus-leukemia effects”  Nature

The BCL-2 protein family: opposing activities that mediate cell death - Nature

The BCL-2 protein family: opposing activities that mediate cell death  Nature

MOMP, cell suicide as a BCL-2 family business - Cell Death & Differentiation - Nature

MOMP, cell suicide as a BCL-2 family business - Cell Death & Differentiation  Nature

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations...

Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations  Nature

Non-apoptotic functions of BCL-2 family proteins - Nature

Non-apoptotic functions of BCL-2 family proteins  Nature

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL - Nature

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL  Nature

Solution structure of the antiapoptotic protein bcl-2 - PNAS

Solution structure of the antiapoptotic protein bcl-2  PNAS

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival - Nature

BCL-XL and MCL-1 are the key BCL-2 family proteins in melanoma cell survival  Nature

Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis | Cell Death Di...

Bcl-2 regulates store-operated Ca2+ entry to modulate ER stress-induced apoptosis | Cell Death Discovery  Nature

Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma - Nature

Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma  Nature

BCL-2 family proteins: changing partners in the dance towards death - Nature

BCL-2 family proteins: changing partners in the dance towards death  Nature

Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling | Cell D...

Targeting Cpt1a-Bcl-2 interaction modulates apoptosis resistance and fibrotic remodeling | Cell Death & Differentiation  Nature

Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition - Nature

Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition  Nature

BCL vertically split compressors - Baker Hughes

BCL vertically split compressors  Baker Hughes

BCL-2 family isoforms in apoptosis and cancer - Nature

BCL-2 family isoforms in apoptosis and cancer  Nature

BCL-2 family: integrating stress responses at the ER to control cell demise | Cell Death & Differ...

BCL-2 family: integrating stress responses at the ER to control cell demise | Cell Death & Differentiation  Nature

Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter’s sy...

Decreased apoptotic priming and loss of BCL-2 dependence are functional hallmarks of Richter’s syndrome  Nature

lncRNA H19 Alleviated Myocardial I/RI via Suppressing miR-877-3p/Bcl-2-Mediated Mitochondrial Apo...

lncRNA H19 Alleviated Myocardial I/RI via Suppressing miR-877-3p/Bcl-2-Mediated Mitochondrial Apoptosis  ScienceDirect.com

Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis | Cell Death & Di...

Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis | Cell Death & Disease  Nature

Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-xL - ScienceDirect.com

Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-xL  ScienceDirect.com

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leuke...

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation  Nature

Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity ...

Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells  Science | AAAS

Why do BCL-2 inhibitors work and where should we use them in the clinic? - Nature

Why do BCL-2 inhibitors work and where should we use them in the clinic?  Nature

Bcl-2-dependent autophagy disruption during aging impairs amino acid utilization that is restored...

Bcl-2-dependent autophagy disruption during aging impairs amino acid utilization that is restored by hochuekkito  Nature

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia...

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia  Nature

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL - ACS Publications

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL  ACS Publications

Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor c...

Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits  Nature

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak - PNAS

Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak  PNAS

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platel...

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets  Nature

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy - Nature

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy  Nature

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family - ScienceDirect...

Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family  ScienceDirect.com

SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung ca...

SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer  Nature

Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testi...

Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1  ScienceDirect.com