"CK2" の関連情報検索結果
CK2 kinase–PRC2 signalling regulates genome-wide H3K27 trimethylation and transduces prolonged co...

Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold - ScienceDirec...

Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold ScienceDirect.com
Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in...

Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells Cancer Cell International
Novel CK2 Inhibitor Silmitasertib Shows Promise in Advanced BCC - Targeted Oncology

Novel CK2 Inhibitor Silmitasertib Shows Promise in Advanced BCC Targeted Oncology
Ellagic Acid and the Metabolite Urolithin A Suppress HSV-1 Infection and Brain Inflammation by Ta...

Ellagic Acid and the Metabolite Urolithin A Suppress HSV-1 Infection and Brain Inflammation by Targeting Casein Kinase CK2 ACS Publications
Picomolar bivalent inhibitors of protein kinase CK2 active against β-coronavirus replication - Sc...

Picomolar bivalent inhibitors of protein kinase CK2 active against β-coronavirus replication ScienceDirect.com
Q&A: Turning THON fundraising into lifesaving medical treatments - Penn State Health News

Q&A: Turning THON fundraising into lifesaving medical treatments Penn State Health News
Hinokiflavone is a novel CK2 inhibitor promoting apoptosis and synergizing with chemotherapeutic ...

Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthes...

Body weight control via protein kinase CK2: diet-induced obesity counteracted by pharmacological ...

Body weight control via protein kinase CK2: diet-induced obesity counteracted by pharmacological targeting ScienceDirect.com
Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 wit...

Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthes...

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL ...

Targeting WDR5/ATAD2 signaling by the CK2/IKAROS axis demonstrates therapeutic efficacy in T-ALL ScienceDirect.com
Missense mutation in the activation segment of the kinase CK2 models Okur-Chung neurodevelopmenta...

Scaffold hopping and sidechain modification from a flavone scaffold lead to discovery of potent, ...

Cold Atmospheric Plasma Jet Promotes Wound Healing Through CK2-Coordinated PI3K/AKT and MAPK Sign...

Cold Atmospheric Plasma Jet Promotes Wound Healing Through CK2-Coordinated PI3K/AKT and MAPK Signaling Pathways ScienceDirect.com
MOTS-c modulates skeletal muscle function by directly binding and activating CK2 - ScienceDirect.com

MOTS-c modulates skeletal muscle function by directly binding and activating CK2 ScienceDirect.com
Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks - Sci...

Phosphorylation-dependent charge blocks regulate the relaxation of nuclear speckle networks ScienceDirect.com
CK2-dependent SK channel dysfunction as contributor to neuronal hyperexcitability in Alzheimer’s ...

CK2-dependent SK channel dysfunction as contributor to neuronal hyperexcitability in Alzheimer’s disease ScienceDirect.com
Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliora...

Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the CK2/AKT pathway ScienceDirect.com
Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting - ScienceDirec...

Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting ScienceDirect.com
A comprehensive review on the dynamics of protein kinase CK2 in cancer development and optimizing...

A comprehensive review on the dynamics of protein kinase CK2 in cancer development and optimizing therapeutic strategies ScienceDirect.com
(PDF) The protein kinase CK2 catalytic domain from Plasmodium falciparum: Crystal structure, tyro...

(PDF) The protein kinase CK2 catalytic domain from Plasmodium falciparum: Crystal structure, tyrosine kinase activity and inhibition researchgate.net
Neuropilin-1-target self-assembled peptide nanoparticles contribute to tumor treatment by inducin...

Casein kinase II (CK2) inhibitors - researchgate.net

Casein kinase II (CK2) inhibitors researchgate.net
Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/St...

LMP1, miRNA-BART-3p and CK2 regulate the PI3K/Akt signaling pathway.... - researchgate.net

LMP1, miRNA-BART-3p and CK2 regulate the PI3K/Akt signaling pathway.... researchgate.net
Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24 -deficient mice - Nature

Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24 -deficient mice Nature
Figure 3. Identification of CK2 substrates using an... - researchgate.net

Figure 3. Identification of CK2 substrates using an... researchgate.net
Protein Kinase CK2 in Cancer Energetics - Frontiers

Protein Kinase CK2 in Cancer Energetics Frontiers
Figure 8: Involvement of Bcr-Abl and CK2 in MEK/ERK1/2 and... - researchgate.net

Figure 8: Involvement of Bcr-Abl and CK2 in MEK/ERK1/2 and... researchgate.net
Targeting CK2 in cancer: a valuable strategy or a waste of time? - Nature

Targeting CK2 in cancer: a valuable strategy or a waste of time? Nature
Therapeutic targeting of CK2 in acute and chronic leukemias - Nature

Therapeutic targeting of CK2 in acute and chronic leukemias Nature
Inside the hellish design of the Crusader Kings video games - The Verge

Inside the hellish design of the Crusader Kings video games The Verge
Protein kinase CK2: a potential therapeutic target for diverse human diseases - Nature

Protein kinase CK2: a potential therapeutic target for diverse human diseases Nature
Figure 1: Involvement of protein kinase CK2 in blood tumor-associated... - researchgate.net

Figure 1: Involvement of protein kinase CK2 in blood tumor-associated... researchgate.net
Figure 3. In vitro phosphorylation followed by LC-MS/MS demonstrates... - researchgate.net

Figure 3. In vitro phosphorylation followed by LC-MS/MS demonstrates... researchgate.net
The ARK2N–CK2 complex initiates transcription-coupled repair through enhancing the interaction of...

Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization...

Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization Acta Neuropathologica Communications
CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection - ScienceDi...

CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection ScienceDirect.com
Role of protein kinase CK2 in antitumor drug resistance - Journal of Experimental & Clinical Canc...

Role of protein kinase CK2 in antitumor drug resistance Journal of Experimental & Clinical Cancer Research
Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the ...

Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket ScienceDirect.com
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors | Scientific R...

A CK2 and SUMO-dependent, PML NB-involved regulatory mechanism controlling BLM ubiquitination and...

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem ce...

Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin–prot...

Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin–proteasome pathway ScienceDirect.com
Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy - Science | AAAS

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy Science | AAAS
Pharmacological inhibition of CK2 by silmitasertib mitigates sepsis-induced circulatory collapse,...

Pharmacological inhibition of CK2 by silmitasertib mitigates sepsis-induced circulatory collapse, thus improving septic outcomes in mice ScienceDirect.com
Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β ...

Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective ACS Publications
Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal E...

Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons Journal of Neuroscience
Copper Modulates the Catalytic Activity of Protein Kinase CK2 - Frontiers

Copper Modulates the Catalytic Activity of Protein Kinase CK2 Frontiers
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregula...

CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease Acta Neuropathologica Communications
CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis - PNAS

CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis PNAS
CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site - ...

CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site Nature
CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis - Na...

CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis Nature
Dual Targeting Novel WDR5/ATAD2 Oncogenic Signaling through CK2/Ikaros Axis Demonstrates Synergis...

Dual Targeting Novel WDR5/ATAD2 Oncogenic Signaling through CK2/Ikaros Axis Demonstrates Synergistic Efficacy in T-ALL ScienceDirect.com
Comparing the efficacy and selectivity of Ck2 inhibitors. A phosphoproteomics approach - ScienceD...

Comparing the efficacy and selectivity of Ck2 inhibitors. A phosphoproteomics approach ScienceDirect.com
CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity - Nature

CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity Nature
Mechanism of CK2 Inhibition by a Ruthenium-Based Polyoxometalate - Frontiers

Mechanism of CK2 Inhibition by a Ruthenium-Based Polyoxometalate Frontiers
Au@CeO2 yolk-shell nanozymes restore mitochondrial dynamics and enhance chondrogenic drug respons...

Au@CeO2 yolk-shell nanozymes restore mitochondrial dynamics and enhance chondrogenic drug response for cartilage regeneration in osteoarthritis ScienceDirect.com
Full article: CSNK2/CK2 regulates selective autophagy of the endoplasmic reticulum - Taylor & Fra...

Full article: CSNK2/CK2 regulates selective autophagy of the endoplasmic reticulum Taylor & Francis Online
Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation - Nature

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation Nature
CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders - Front...

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders Frontiers
Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2...

Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2 ScienceDirect.com
Development of a potent and selective chemical probe for the pleiotropic kinase CK2 - ScienceDire...

Development of a potent and selective chemical probe for the pleiotropic kinase CK2 ScienceDirect.com
Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization -...

Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization Nature
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly - Nature

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly Nature
Evaluation of a Selective Chemical Probe Validates That CK2 Mediates Neuroinflammation in a Human...

CK2 inhibition with silmitasertib promotes methuosis-like cell death associated to catastrophic m...

ROS elevate HIF-1α phosphorylation for insect lifespan through the CK2-MKP3-p38 pathway - Science...

ROS elevate HIF-1α phosphorylation for insect lifespan through the CK2-MKP3-p38 pathway ScienceDirect.com
Protein kinase CK2-dependent aerobic glycolysis-induced lactate dehydrogenase A enhances the migr...

Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by compl...

Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin ScienceDirect.com
Association of protein kinase CK2 inhibition with cellular radiosensitivity of non-small cell lun...

Figure 3. 3D binding mode of the four tested compounds with the ATP... - researchgate.net

Figure 3. 3D binding mode of the four tested compounds with the ATP... researchgate.net
Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome ...

Targeting CK2-mediated phosphorylation of p53R2 sensitizes BRCA -proficient cancer cells to PARP ...

The regulatory subunits of CK2 complex mediate DNA damage response and virulence in Candida Glabr...

The regulatory subunits of CK2 complex mediate DNA damage response and virulence in Candida Glabrata BMC Microbiology
Crusader Kings 2 DLC – the complete guide - PCGamesN

Protein kinase CK2 is necessary for the adipogenic differentiation of human mesenchymal stem cell...

Protein kinase CK2 is necessary for the adipogenic differentiation of human mesenchymal stem cells ScienceDirect.com
Circumventing drug resistance through a CK2-targeted combination via attenuating endogenous AhR-T...

Circumventing drug resistance through a CK2-targeted combination via attenuating endogenous AhR-TLS-promoted genomic instability in human colorectal cancer cells ScienceDirect.com
Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection - Frontiers

Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection Frontiers
A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient ...

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a - ScienceDirect.com

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a ScienceDirect.com
Transformative Tech – CK2 Technologies - Towne Post Network -

Transformative Tech – CK2 Technologies Towne Post Network -
“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms - S...

“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms ScienceDirect.com
Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer...

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex - Nature

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex Nature
Blockade of chemo-resistance to 5-FU by a CK2-targeted combination via attenuating AhR-TLS-promot...

Blockade of chemo-resistance to 5-FU by a CK2-targeted combination via attenuating AhR-TLS-promoted genomic instability in human colon cancer cells ScienceDirect.com
Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a...

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma Science | AAAS
IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymph...

IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia ScienceDirect.com
Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Ene...

Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure ScienceDirect.com
The best Crusader Kings 2 mods - PCGamesN

The best Crusader Kings 2 mods PCGamesN
Inhibition of corticosterone synthesis impairs cued water maze consolidation, but it does not aff...

Small molecule modulators targeting protein kinase CK1 and CK2 - ScienceDirect.com

Small molecule modulators targeting protein kinase CK1 and CK2 ScienceDirect.com
Casein kinase 2 (CK2) increases survivin expression via enhanced β-catenin–T cell factor/lymphoid...

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated M...

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy ScienceDirect.com
The upstream stimulatory factor USF1 is regulated by protein kinase CK2 phosphorylation - Science...

The upstream stimulatory factor USF1 is regulated by protein kinase CK2 phosphorylation ScienceDirect.com
Protein Kinase CK2 represents a new target to boost Ibrutinib and Venetoclax induced cytotoxicity...

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability - ...

CK2 Phospho-Dependent Binding of R2TP Complex to TEL2 Is Essential for mTOR and SMG1 Stability ScienceDirect.com
Crusader Kings 2: The Old Gods Review - GameGrin
