"CK2" の関連情報検索結果

Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenoc...



Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cells  Nature

Picomolar bivalent inhibitors of protein kinase CK2 active against β-coronavirus replication - Sc...



Picomolar bivalent inhibitors of protein kinase CK2 active against β-coronavirus replication  ScienceDirect.com

Novel CK2 Inhibitor Silmitasertib Shows Promise in Advanced BCC - Targeted Oncology



Novel CK2 Inhibitor Silmitasertib Shows Promise in Advanced BCC  Targeted Oncology

Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthes...



Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthesis, Biological Evaluation, and Structural Studies on E-/Z-Isomers  ACS Publications

CK2 kinase–PRC2 signalling regulates genome-wide H3K27 trimethylation and transduces prolonged co...



CK2 kinase–PRC2 signalling regulates genome-wide H3K27 trimethylation and transduces prolonged cold exposure into epigenetic cold memory in plants  Nature

Q&A: Turning THON fundraising into lifesaving medical treatments - Penn State Health News



Q&A: Turning THON fundraising into lifesaving medical treatments  Penn State Health News

Neuropilin-1-target self-assembled peptide nanoparticles contribute to tumor treatment by inducin...



Neuropilin-1-target self-assembled peptide nanoparticles contribute to tumor treatment by inducing pyroptosis  BMC Cancer

Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliora...



Kirenol alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the CK2/AKT pathway  ScienceDirect.com

Inside the hellish design of the Crusader Kings video games - The Verge



Inside the hellish design of the Crusader Kings video games  The Verge

Hinokiflavone is a novel CK2 inhibitor promoting apoptosis and synergizing with chemotherapeutic ...



Hinokiflavone is a novel CK2 inhibitor promoting apoptosis and synergizing with chemotherapeutic agents in cisplatin resistant bladder cancer cells  Nature

Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthes...



Discovery of 7,9-Dibromo-dihydrodibenzofuran as a Potent Casein Kinase 2 (CK2) Inhibitor: Synthesis, Biological Evaluation, and Structural Studies on E-/Z-Isomers  ACS Publications

Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 wit...



Correction: Small molecule induces mitochondrial fusion for neuroprotection via targeting CK2 without affecting its conventional kinase activity | Signal Transduction and Targeted Therapy  Nature

Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24 -deficient mice - Nature



Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24 -deficient mice  Nature

Therapeutic targeting of CK2 in acute and chronic leukemias - Nature



Therapeutic targeting of CK2 in acute and chronic leukemias  Nature

Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors | Scientific R...



Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors | Scientific Reports  Nature

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem ce...



Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease  Nature

CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site - ...



CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site  Nature

A CK2 and SUMO-dependent, PML NB-involved regulatory mechanism controlling BLM ubiquitination and...



A CK2 and SUMO-dependent, PML NB-involved regulatory mechanism controlling BLM ubiquitination and G-quadruplex resolution  Nature

Association of protein kinase CK2 inhibition with cellular radiosensitivity of non-small cell lun...



Association of protein kinase CK2 inhibition with cellular radiosensitivity of non-small cell lung cancer  Nature

CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity - Nature



CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity  Nature

CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis - PNAS



CK2 phosphorylation of CCA1 is necessary for its circadian oscillator function in Arabidopsis  PNAS

Global Screening of CK2 Kinase Substrates by an Integrated Phosphoproteomics Workflow - Nature



Global Screening of CK2 Kinase Substrates by an Integrated Phosphoproteomics Workflow  Nature

Protein Kinase CK2 in Cancer Energetics - Frontiers



Protein Kinase CK2 in Cancer Energetics  Frontiers

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders - Front...



CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders  Frontiers

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly - Nature



mTORC1 and CK2 coordinate ternary and eIF4F complex assembly  Nature

Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization -...



Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization  Nature

Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation - Nature



Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation  Nature

CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis - Na...



CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis  Nature

Protein kinase CK2-dependent aerobic glycolysis-induced lactate dehydrogenase A enhances the migr...



Protein kinase CK2-dependent aerobic glycolysis-induced lactate dehydrogenase A enhances the migration and invasion of cancer cells  Nature

Missense mutation in the activation segment of the kinase CK2 models Okur-Chung neurodevelopmenta...



Missense mutation in the activation segment of the kinase CK2 models Okur-Chung neurodevelopmental disorder and alters the hippocampal glutamatergic synapse | Molecular Psychiatry  Nature

Comparing the efficacy and selectivity of Ck2 inhibitors. A phosphoproteomics approach - ScienceD...



Comparing the efficacy and selectivity of Ck2 inhibitors. A phosphoproteomics approach  ScienceDirect.com

ROS elevate HIF-1α phosphorylation for insect lifespan through the CK2-MKP3-p38 pathway - Science...



ROS elevate HIF-1α phosphorylation for insect lifespan through the CK2-MKP3-p38 pathway  ScienceDirect.com

The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells - Nature



The protein kinase CK2 contributes to the malignant phenotype of cholangiocarcinoma cells  Nature

Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal E...



Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons  Journal of Neuroscience

Coumarin as Attractive Casein Kinase 2 (CK2) Inhibitor Scaffold: An Integrate Approach To Elucida...



Coumarin as Attractive Casein Kinase 2 (CK2) Inhibitor Scaffold: An Integrate Approach To Elucidate the Putative Binding Motif and Explain Structure–Activity Relationships  ACS Publications

A comprehensive review on the dynamics of protein kinase CK2 in cancer development and optimizing...



A comprehensive review on the dynamics of protein kinase CK2 in cancer development and optimizing therapeutic strategies  ScienceDirect.com

The regulatory subunits of CK2 complex mediate DNA damage response and virulence in Candida Glabr...



The regulatory subunits of CK2 complex mediate DNA damage response and virulence in Candida Glabrata  BMC Microbiology

Targeting CK2-mediated phosphorylation of p53R2 sensitizes BRCA -proficient cancer cells to PARP ...



Targeting CK2-mediated phosphorylation of p53R2 sensitizes BRCA -proficient cancer cells to PARP inhibitors  Nature

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient ...



A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours  Nature

Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer...



Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells  Nature

Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by compl...



Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin  ScienceDirect.com

Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection - Frontiers



Myeloid Cell CK2 Regulates Inflammation and Resistance to Bacterial Infection  Frontiers

Dual Targeting Novel WDR5/ATAD2 Oncogenic Signaling through CK2/Ikaros Axis Demonstrates Synergis...



Dual Targeting Novel WDR5/ATAD2 Oncogenic Signaling through CK2/Ikaros Axis Demonstrates Synergistic Efficacy in T-ALL  ScienceDirect.com

Protein kinase CK2 enables regulatory T cells to suppress excessive T - Nature



Protein kinase CK2 enables regulatory T cells to suppress excessive T  Nature

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy - Science | AAAS



Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy  Science | AAAS

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex - Nature



MRE11 stability is regulated by CK2-dependent interaction with R2TP complex  Nature

Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/St...



Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation  Nature

Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin–prot...



Chemically induced degradation of CK2 by proteolysis targeting chimeras based on a ubiquitin–proteasome pathway  ScienceDirect.com

“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms - S...



“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms  ScienceDirect.com

Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Ene...



Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure  ScienceDirect.com

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a...



Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma  Science | AAAS

Transformative Tech – CK2 Technologies - Towne Post Network -



Transformative Tech – CK2 Technologies  Towne Post Network -

Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis - PNAS



Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis  PNAS

Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting - ScienceDirec...



Synthesis and evaluation of chemical linchpins for highly selective CK2α targeting  ScienceDirect.com

A New Chemical Probe Challenges the Broad Cancer Essentiality of CK2 - ScienceDirect.com



A New Chemical Probe Challenges the Broad Cancer Essentiality of CK2  ScienceDirect.com

Crusader Kings 2: The Old Gods Review - GameGrin



Crusader Kings 2: The Old Gods Review  GameGrin

GTP plus water mimic ATP in the active site of protein kinase CK2 - Nature



GTP plus water mimic ATP in the active site of protein kinase CK2  Nature

CK2 regulates 5-HT4 receptor signaling and modulates depressive-like behavior | Molecular Psychia...



CK2 regulates 5-HT4 receptor signaling and modulates depressive-like behavior | Molecular Psychiatry  Nature

Crusader Kings 2 DLC - the complete guide - PCGamesN



Crusader Kings 2 DLC - the complete guide  PCGamesN

CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment - Frontiers



CK2 Phosphorylating I2PP2A/SET Mediates Tau Pathology and Cognitive Impairment  Frontiers

Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes - EMBO Press



Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes  EMBO Press

New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes - ACS Publi...



New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes  ACS Publications

Inhibition of corticosterone synthesis impairs cued water maze consolidation, but it does not aff...



Inhibition of corticosterone synthesis impairs cued water maze consolidation, but it does not affect the expression of BDNF, CK2 and SGK1 genes in dorsal striatum  Frontiers

The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine ...



The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition  Nature

The upstream stimulatory factor USF1 is regulated by protein kinase CK2 phosphorylation - Science...



The upstream stimulatory factor USF1 is regulated by protein kinase CK2 phosphorylation  ScienceDirect.com

Phosphoproteomics Reveals HMGA1, a CK2 Substrate, as a Drug-Resistant Target in Non-Small Cell Lu...



Phosphoproteomics Reveals HMGA1, a CK2 Substrate, as a Drug-Resistant Target in Non-Small Cell Lung Cancer  Nature

CK2 blockade alleviates liver fibrosis by suppressing activation of hepatic stellate cells via th...



CK2 blockade alleviates liver fibrosis by suppressing activation of hepatic stellate cells via the Hedgehog pathway  British Pharmacological Society | Journals

The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated ...



The PP2A-like Protein Phosphatase Ppg1 and the Far Complex Cooperatively Counteract CK2-Mediated Phosphorylation of Atg32 to Inhibit Mitophagy  ScienceDirect.com

The best Crusader Kings 2 mods - PCGamesN



The best Crusader Kings 2 mods  PCGamesN

SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAP...



SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways  Nature

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migrati...



Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration  Nature

Activation of protein kinase CK2 attenuates FOXO3a functioning in a PML-dependent manner: implica...



Activation of protein kinase CK2 attenuates FOXO3a functioning in a PML-dependent manner: implications in human prostate cancer  Nature

Crusader Kings 3: 10 Features From Crusader Kings 2 We Can't Wait To See - TheGamer



Crusader Kings 3: 10 Features From Crusader Kings 2 We Can't Wait To See  TheGamer

Protein kinase CK2 phosphorylates and upregulates Akt/PKB - Nature



Protein kinase CK2 phosphorylates and upregulates Akt/PKB  Nature

Behold, My New Favorite Crusader Kings Bug - Kotaku



Behold, My New Favorite Crusader Kings Bug  Kotaku

Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis - Nature



Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis  Nature

A PACS‐1, GGA3 and CK2 complex regulates CI‐MPR trafficking - EMBO Press



A PACS‐1, GGA3 and CK2 complex regulates CI‐MPR trafficking  EMBO Press

Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells - Scientific Reports - Nature



Generation and quantitative proteomics analysis of CK2α/α’(−/−) cells - Scientific Reports  Nature

GSK-3 and CK2 Kinases Converge on Timeless to Regulate the Master Clock - ScienceDirect.com



GSK-3 and CK2 Kinases Converge on Timeless to Regulate the Master Clock  ScienceDirect.com

CK2 inhibitor DMAT ameliorates spinal cord injury by increasing autophagy and inducing anti-infla...



CK2 inhibitor DMAT ameliorates spinal cord injury by increasing autophagy and inducing anti-inflammatory microglial polarization  ScienceDirect.com

Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as...



Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase  ScienceDirect.com

Epstein-Barr Virus Nuclear Antigen 1 Hijacks the Host Kinase CK2 To Disrupt PML Nuclear Bodies - ...



Epstein-Barr Virus Nuclear Antigen 1 Hijacks the Host Kinase CK2 To Disrupt PML Nuclear Bodies  ASM Journals

A Peptide-Based Target Screen Implicates the Protein Kinase CK2 in the Global Regulation of Caspa...



A Peptide-Based Target Screen Implicates the Protein Kinase CK2 in the Global Regulation of Caspase Signaling  Science | AAAS

Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemi...



Activity of the clinical-stage CK2-specific inhibitor CX-4945 against chronic lymphocytic leukemia  Nature

The best Crusader Kings 2 expansions, from Old Gods to Monks and Mystics - PC Gamer



The best Crusader Kings 2 expansions, from Old Gods to Monks and Mystics  PC Gamer

Crusader Kings 3 is happening: here's ten things we know so far - Rock Paper Shotgun



Crusader Kings 3 is happening: here's ten things we know so far  Rock Paper Shotgun

How the Roman Empire Beat the Aztec Invaders and made CK2 my GOTY - Giant Bomb



How the Roman Empire Beat the Aztec Invaders and made CK2 my GOTY  Giant Bomb

Protein kinase CK2 regulates AKT, NF-κB and STAT3 activation, stem cell viability and proliferati...



Protein kinase CK2 regulates AKT, NF-κB and STAT3 activation, stem cell viability and proliferation in acute myeloid leukemia  Nature

Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours - Nature



Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours  Nature

Emerging roles of protein kinase CK2 in abscisic acid signaling - Frontiers



Emerging roles of protein kinase CK2 in abscisic acid signaling  Frontiers

Protein kinase CK2 in hematologic malignancies: reliance on a pivotal cell survival regulator by ...



Protein kinase CK2 in hematologic malignancies: reliance on a pivotal cell survival regulator by oncogenic signaling pathways | Leukemia  Nature

A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochem...



A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods  Nature

Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflam...



Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation  Nature

Emerging role of Protein Kinase CK2 in Tumor immunity - Frontiers



Emerging role of Protein Kinase CK2 in Tumor immunity  Frontiers

Effect of histidine protonation state on ligand binding at the ATP-binding site of human protein ...



Effect of histidine protonation state on ligand binding at the ATP-binding site of human protein kinase CK2  Nature

Casein kinase 2 is a critical determinant of the balance of Th17 and Treg cell differentiation - ...



Casein kinase 2 is a critical determinant of the balance of Th17 and Treg cell differentiation  Nature

Targeting CK2-driven non-oncogene addiction in B-cell tumors - Nature



Targeting CK2-driven non-oncogene addiction in B-cell tumors  Nature

Plk1 and CK2 Act in Concert to Regulate Rad51 during DNA Double Strand Break Repair - ScienceDire...



Plk1 and CK2 Act in Concert to Regulate Rad51 during DNA Double Strand Break Repair  ScienceDirect.com

Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK...



Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway  Frontiers

Crusader Kings 2 easter egg lets you rule an animal kingdom - PC Gamer



Crusader Kings 2 easter egg lets you rule an animal kingdom  PC Gamer