Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longev...

Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity | Scientific Reports  Nature

Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity - Frontiers

Efficacy of cartilage-targeted IGF-1 in a mouse model of growth hormone insensitivity  Frontiers

IGF-1 Provides Protective Role in Arteriosclerotic Cerebral Small Vessel Disease - American Heart...

IGF-1 Provides Protective Role in Arteriosclerotic Cerebral Small Vessel Disease  American Heart Association Journals

Brain miR-137 governs growth and development via GH/IGF-1 signaling - BMC Biology

Brain miR-137 governs growth and development via GH/IGF-1 signaling  BMC Biology

Alteration of IGF-1 bioavailability due to PAPPA2 deficiency leads to sex-specific metabolic dist...

Alteration of IGF-1 bioavailability due to PAPPA2 deficiency leads to sex-specific metabolic disturbances  ScienceDirect.com

Exploring IGF-1 Pathway Biomarkers and Outcomes in Metastatic Hormone-Sensitive Prostate Cancer -...

Exploring IGF-1 Pathway Biomarkers and Outcomes in Metastatic Hormone-Sensitive Prostate Cancer - Lisa Horvath  UroToday

Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies - Frontiers

Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies  Frontiers

An organoid library unveils subtype-specific IGF-1 dependency via a YAP–AP1 axis in human small c...

An organoid library unveils subtype-specific IGF-1 dependency via a YAP–AP1 axis in human small cell lung cancer  Nature

L-Citrulline Improves IGF-1 Signaling Pathway in Preeclampsia via Polyamines - American Heart Ass...

L-Citrulline Improves IGF-1 Signaling Pathway in Preeclampsia via Polyamines  American Heart Association Journals

Gut-derived IL-13 contributes to growth via promoting hepatic IGF-1 production - BioMed Central

Gut-derived IL-13 contributes to growth via promoting hepatic IGF-1 production  BioMed Central

The effect of modulation Piezo2 by IGF-1 on tactile hypersensitivity in BTBR model mice - Science...

The effect of modulation Piezo2 by IGF-1 on tactile hypersensitivity in BTBR model mice  ScienceDirect.com

Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early p...

Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty  Frontiers

Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male ...

Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice  Nature

IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution -...

IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution  ScienceDirect.com

Association of IGF-1 and IGFBP-3 with metabolic abnormalities among children and adolescents - Fr...

Association of IGF-1 and IGFBP-3 with metabolic abnormalities among children and adolescents  Frontiers

Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts - Nature

Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts  Nature

Running in mice increases the expression of brain hemoglobin-related genes interacting with the G...

Running in mice increases the expression of brain hemoglobin-related genes interacting with the GH/IGF-1 system  Nature

IGF-1 levels in the general population, heart failure patients, and individuals with acromegaly: ...

IGF-1 levels in the general population, heart failure patients, and individuals with acromegaly: differences and projections from meta-analyses—a dual perspective  Frontiers

IGF-1 c.258 A > G synonymous mutation ameliorates senile osteoporosis - Nature

IGF-1 c.258 A > G synonymous mutation ameliorates senile osteoporosis  Nature

Systemic IGF-1 administration prevents traumatic brain injury induced gut permeability, dysmorphi...

Systemic IGF-1 administration prevents traumatic brain injury induced gut permeability, dysmorphia, dysbiosis, and the increased number of immature dentate granule cells  Acta Neuropathologica Communications

Vitamin D and exercise improve VEGF-B production and IGF-1 levels in diabetic rats: insights the ...

Vitamin D and exercise improve VEGF-B production and IGF-1 levels in diabetic rats: insights the role of miR-1 suppression | Scientific Reports  Nature

Abstract 4139404: Post-Translational Regulation of Larp6 by IGF-1 Modulates Collagen Synthesis in...

Abstract 4139404: Post-Translational Regulation of Larp6 by IGF-1 Modulates Collagen Synthesis in Smooth Muscle Cells  American Heart Association Journals

Predictive value of IGF-1/IGFBP-3 ratio for thyroid nodules in type 2 diabetic mellitus - Frontiers

Predictive value of IGF-1/IGFBP-3 ratio for thyroid nodules in type 2 diabetic mellitus  Frontiers

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep - American Phys...

IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep  American Physiological Society Journal

Enhancement of therapeutic potential of mesenchymal stem cell by IGF-1 delivery in PLGA microsphe...

Enhancement of therapeutic potential of mesenchymal stem cell by IGF-1 delivery in PLGA microspheres for tissue regeneration  ScienceDirect.com

Clinical characteristics and treatment efficacy in patients with primary severe IGF-1 deficiency ...

Clinical characteristics and treatment efficacy in patients with primary severe IGF-1 deficiency treated with recombinant IGF-1  Frontiers

Nutra IGF Under Review: Best OTC Liquid HGH Booster IGF-1 Growth Factor Drops by GDR Labs - Yahoo...

Nutra IGF Under Review: Best OTC Liquid HGH Booster IGF-1 Growth Factor Drops by GDR Labs  Yahoo Finance

IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritis - N...

IGF1 drives Wnt-induced joint damage and is a potential therapeutic target for osteoarthritis  Nature

Losartan rewires the tumor-immune microenvironment and suppresses IGF-1 to overcome resistance to...

Losartan rewires the tumor-immune microenvironment and suppresses IGF-1 to overcome resistance to chemo-immunotherapy in ovarian cancer | British Journal of Cancer  Nature

IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathway...

IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing  ScienceDirect.com

The Growth Hormone-IGF-1 axis is a risk factor for Long-Term Kidney Allograft Failure - medRxiv

The Growth Hormone-IGF-1 axis is a risk factor for Long-Term Kidney Allograft Failure  medRxiv

Causal relationship between gut microbiota and insulin-like growth factor 1: a bidirectional two-...

Causal relationship between gut microbiota and insulin-like growth factor 1: a bidirectional two-sample Mendelian randomization study  Frontiers

Unraveling the relationship among insulin resistance, IGF-1, and amyloid-beta 1–40: Is the defini...

Unraveling the relationship among insulin resistance, IGF-1, and amyloid-beta 1–40: Is the definition of type 3 diabetes applicable in the cardiovascular field?  ScienceDirect.com

New insights on the cardiovascular effects of IGF-1 - Frontiers

New insights on the cardiovascular effects of IGF-1  Frontiers

Insulin-like growth factor-1 level is a poor diagnostic indicator of growth hormone deficiency - ...

Insulin-like growth factor-1 level is a poor diagnostic indicator of growth hormone deficiency  Nature

Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions - ScienceDir...

Protective role of IGF-1 and GLP-1 signaling activation in neurological dysfunctions  ScienceDirect.com

Role of the IGF-1 Axis in Overcoming Resistance in Breast Cancer - Frontiers

Role of the IGF-1 Axis in Overcoming Resistance in Breast Cancer  Frontiers

The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Ag...

The Role of the IGF-1 Signaling Cascade in Muscle Protein Synthesis and Anabolic Resistance in Aging Skeletal Muscle  Frontiers

Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection - Nature

Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection  Nature

ROLE of IGF-1 System in the Modulation of Longevity: Controversies and New Insights From a Centen...

ROLE of IGF-1 System in the Modulation of Longevity: Controversies and New Insights From a Centenarians' Perspective  Frontiers

Obesity and endocrine-related cancer: The important role of IGF-1 - Frontiers

Obesity and endocrine-related cancer: The important role of IGF-1  Frontiers

Titrating Growth Hormone Dose to High-Normal IGF-1 Levels Has Beneficial Effects on Body Fat Dist...

Titrating Growth Hormone Dose to High-Normal IGF-1 Levels Has Beneficial Effects on Body Fat Distribution and Microcirculatory Function Despite Causing Insulin Resistance  Frontiers

Regulation of IGF -1 signaling by microRNAs - Frontiers

Regulation of IGF -1 signaling by microRNAs  Frontiers

Mutations Affecting Mammalian Aging: GH and GHR vs IGF-1 and Insulin - Frontiers

Mutations Affecting Mammalian Aging: GH and GHR vs IGF-1 and Insulin  Frontiers

BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism - Nature

BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism  Nature

Gut development following insulin-like growth factor-1 supplementation to preterm pigs - Nature

Gut development following insulin-like growth factor-1 supplementation to preterm pigs  Nature

Is insulin-like growth factor-1 involved in Parkinson’s disease development? - Journal of Transla...

Is insulin-like growth factor-1 involved in Parkinson’s disease development?  Journal of Translational Medicine

Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment - Arthrit...

Insulin-like growth factor-1 in articular cartilage repair for osteoarthritis treatment  Arthritis Research & Therapy

Association of Insulin-like Growth Factor 1 Concentrations with Risk for and Prognosis of Amyotro...

Association of Insulin-like Growth Factor 1 Concentrations with Risk for and Prognosis of Amyotrophic Lateral Sclerosis – Results from the ALS Registry Swabia  Nature

Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising th...

Identification of the molecular mechanism of insulin-like growth factor-1 (IGF-1): a promising therapeutic target for neurodegenerative diseases associated with metabolic syndrome  Cell & Bioscience

Insulin-like growth factor-1 levels are associated with high comorbidity of metabolic disorders i...

Insulin-like growth factor-1 levels are associated with high comorbidity of metabolic disorders in obese subjects; a Japanese single-center, retrospective-study | Scientific Reports  Nature

IGF-1 and the World Anti-Doping Agency Prohibited List - U.S. Anti-Doping Agency (USADA)

IGF-1 and the World Anti-Doping Agency Prohibited List  U.S. Anti-Doping Agency (USADA)

Food Restriction Reveals Individual Differences in Insulin-Like Growth Factor-1 Reaction Norms - ...

Food Restriction Reveals Individual Differences in Insulin-Like Growth Factor-1 Reaction Norms  Frontiers

The influence of metformin on IGF-1 levels in humans: A systematic review and meta-analysis - Sci...

The influence of metformin on IGF-1 levels in humans: A systematic review and meta-analysis  ScienceDirect.com

The association between IGF-1 levels and four types of osteoarthritis: a bidirectional and two-st...

The association between IGF-1 levels and four types of osteoarthritis: a bidirectional and two-step mendelian randomization study  Frontiers

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice - Nature

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice  Nature

The role of insulin-like growth factor-1 in bone remodeling: A review - ScienceDirect.com

The role of insulin-like growth factor-1 in bone remodeling: A review  ScienceDirect.com

IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA - Nature

IGF-1 protects against angiotensin II-induced cardiac fibrosis by targeting αSMA  Nature

Insulin and IGF-1 have both overlapping and distinct effects on CD4 - Nature

Insulin and IGF-1 have both overlapping and distinct effects on CD4  Nature

Neuronal IGF-1 overexpression restores hippocampal newborn cell survival and recent CFC memory co...

Neuronal IGF-1 overexpression restores hippocampal newborn cell survival and recent CFC memory consolidation in Cav1.3 knock-out mice  ScienceDirect.com

Insulin-Like Growth Factor-1 and Neuroinflammation - Frontiers

Insulin-Like Growth Factor-1 and Neuroinflammation  Frontiers

Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time - ScienceDir...

Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time  ScienceDirect.com

Serum cortisol and insulin-like growth factor 1 levels in major depressive disorder and schizophr...

Serum cortisol and insulin-like growth factor 1 levels in major depressive disorder and schizophrenia  Nature

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal ...

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle  Nature

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression - Nature

Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression  Nature

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-lik...

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine  Nature

The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasti...

The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity  ScienceDirect.com

Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full reperto...

Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer  Nature

Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium ex...

Activation of IGF-1 pathway and suppression of atrophy related genes are involved in Epimedium extract (icariin) promoted C2C12 myotube hypertrophy  Nature

Causal associations between insulin-like growth factor 1 and vitamin D levels: a two-sample bidir...

Causal associations between insulin-like growth factor 1 and vitamin D levels: a two-sample bidirectional Mendelian randomization study  Frontiers

IGF-1/IGFBP-3 Ratio in Growth Hormone Deficiency - Endocrine Society

IGF-1/IGFBP-3 Ratio in Growth Hormone Deficiency  Endocrine Society

Diagnosis of Idiopathic GHD in Children Based on Response to rhGH Treatment: The Importance of GH...

Diagnosis of Idiopathic GHD in Children Based on Response to rhGH Treatment: The Importance of GH Provocative Tests and IGF-1  Frontiers

Early IGF-1 Gene Therapy Prevented Oxidative Stress and Cognitive Deficits Induced by Traumatic B...

Early IGF-1 Gene Therapy Prevented Oxidative Stress and Cognitive Deficits Induced by Traumatic Brain Injury  Frontiers

Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist...

Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist  Nature

Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistan...

Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes  Nature

Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by pro...

Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development  Nature

Insulin-like growth factor-1 effects on kidney development in preterm piglets - Nature

Insulin-like growth factor-1 effects on kidney development in preterm piglets  Nature

Challenges in the care of individuals with severe primary insulin-like growth factor-I deficiency...

Challenges in the care of individuals with severe primary insulin-like growth factor-I deficiency (SPIGFD): an international, multi-stakeholder perspective  Orphanet Journal of Rare Diseases

IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter -...

IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter  PNAS

Insulin-Like Growth Factor Pathway and the Thyroid - Frontiers

Insulin-Like Growth Factor Pathway and the Thyroid  Frontiers

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevi...

Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity  American Heart Association Journals

IGF-1 receptor cleavage in hypertension - Nature

IGF-1 receptor cleavage in hypertension  Nature

The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular loca...

The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular localisation and secretion  Nature

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis - ...

Differential Role of Insulin/IGF-1 Receptor Signaling in Muscle Growth and Glucose Homeostasis  ScienceDirect.com

IGF-1-mediated FOXC1 overexpression induces stem-like properties through upregulating CBX7 and IG...

IGF-1-mediated FOXC1 overexpression induces stem-like properties through upregulating CBX7 and IGF-1R in esophageal squamous cell carcinoma  Nature

Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants - ...

Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants  Nature

Anabolic effects of IGF-1 signaling on the skeleton - Frontiers

Anabolic effects of IGF-1 signaling on the skeleton  Frontiers

LRP1 mediates the IGF-1-induced GLUT1 expression on the cell surface and glucose uptake in Müller...

LRP1 mediates the IGF-1-induced GLUT1 expression on the cell surface and glucose uptake in Müller glial cells  Nature

Structural basis of the activation of type 1 insulin-like growth factor receptor - Nature

Structural basis of the activation of type 1 insulin-like growth factor receptor  Nature

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity - PNAS

Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity  PNAS

IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades - Nature

IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades  Nature

Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Rev...

Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression  ScienceDirect.com

Insulin mediates de novo nuclear accumulation of the IGF-1/insulin Hybrid Receptor in corneal epi...

Insulin mediates de novo nuclear accumulation of the IGF-1/insulin Hybrid Receptor in corneal epithelial cells  Nature

Insulin-like growth factor 1 injection changes gene expression related to amino acid transporting...

Insulin-like growth factor 1 injection changes gene expression related to amino acid transporting, complement and coagulation cascades in the stomach of tilapia revealed by RNA-seq  Frontiers

Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blo...

Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade  Nature

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration - ...

Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration  PNAS

Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralisi...

Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours  Nature

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex - Nature

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex  Nature

The Value of IGF-1 and IGFBP-1 in Patients With Heart Failure With Reduced, Mid-range, and Preser...

The Value of IGF-1 and IGFBP-1 in Patients With Heart Failure With Reduced, Mid-range, and Preserved Ejection Fraction  Frontiers

In Type 1 diabetes, verapamil prevents decline of IGF-1 and promotes beta-cell IGF-1 signaling - ...

In Type 1 diabetes, verapamil prevents decline of IGF-1 and promotes beta-cell IGF-1 signaling  University of Alabama at Birmingham