"IL-2" の関連情報検索結果

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial - FirstWor...



Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial  FirstWord Pharma

Gluten-Stimulated Interleukin-2 Secretion Useful for Diagnosing Celiac Disease - Physician's Weekly



Gluten-Stimulated Interleukin-2 Secretion Useful for Diagnosing Celiac Disease  Physician's Weekly

Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune respons...



Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response  Nature

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals - ...



A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals  Science | AAAS

Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression - ScienceD...



Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression  ScienceDirect.com

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, dou...



Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial  The Lancet

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alter...



Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alternatives  Fierce Biotech

Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for trea...



Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for treatment outcomes in non-small cell Lung Cancer patients undergoing anti-PD1 therapy  Frontiers

Adding low-dose IL-2 to riluzole may improve survival in ALS - ALS News Today



Adding low-dose IL-2 to riluzole may improve survival in ALS  ALS News Today

Cue Biopharma Receives FDA Feedback on Pre-IND Briefing Document Reinforcing Company’s Intention ...



Cue Biopharma Receives FDA Feedback on Pre-IND Briefing Document Reinforcing Company’s Intention to Advance IND Submission for CUE-401 to Address Unmet Need in the Treatment of Autoimmune Disease  TradingView

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8 - Nature



TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8  Nature

An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to...



An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy  ScienceDirect.com

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentia...



Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy  Science | AAAS

Examining the evidence for IL-2 in amyotrophic lateral sclerosis - The Lancet



Examining the evidence for IL-2 in amyotrophic lateral sclerosis  The Lancet

Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells fo...



Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells following acute coronary syndrome  Nature

Biomineral tablets for long-acting IL-2 immunotherapy - Nature



Biomineral tablets for long-acting IL-2 immunotherapy  Nature

CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communic...



CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communications  Nature

Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficac...



Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficacy in mouse autoimmune models  Nature

An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammat...



An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammatory CAR macrophages in renal cell carcinoma  Nature

The Interleukin-2 Market is Set to Reach USD 4 Billion by 2034, Driven by IL-2 Targeting Fusion P...



The Interleukin-2 Market is Set to Reach USD 4 Billion by 2034, Driven by IL-2 Targeting Fusion Proteins, Monoclonal antibodies, and Gene Therapies Across Immunology, Dermatology, Neurodegenerative Disorders, and Oncology | DelveInsight  PR Newswire

A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells agains...



A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma  Science | AAAS

IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines - PNAS



IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines  PNAS

Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing...



Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing immunotherapy  ScienceDirect.com

National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik - Vintage Aviatio...



National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik  Vintage Aviation News

Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 ove...



Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer  Nature

Whole Blood Immune Sensor Offers Non-Invasive Celiac Detection - AZoSensors



Whole Blood Immune Sensor Offers Non-Invasive Celiac Detection  AZoSensors

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T - Nature



Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T  Nature

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...



Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective and emerging trends  Nature

Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emi...



Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography  ScienceDirect.com

A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythemat...



A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythematosus  Frontiers

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People wi...



Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People with Systemic Lupus Erythematosus  Lupus Foundation of America

First-in-human evaluation of a no-alpha interleukin–2 mutein: safety and preliminary pharmacodyna...



First-in-human evaluation of a no-alpha interleukin–2 mutein: safety and preliminary pharmacodynamic and clinical effect  Frontiers

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...



T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics  Nature

Based on the immune system: the role of the IL-2 family in pancreatic disease - Frontiers



Based on the immune system: the role of the IL-2 family in pancreatic disease  Frontiers

WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game - DualShockers



WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game  DualShockers

Targeting systemic IL-2 to BCMA CAR-T cells - Nature



Targeting systemic IL-2 to BCMA CAR-T cells  Nature

GI Innovation wins US patent for dual-action IL-2 therapy targeting cold tumors - koreabiomed.com



GI Innovation wins US patent for dual-action IL-2 therapy targeting cold tumors  koreabiomed.com

Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy - OncLive



Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy  OncLive

IL-2 and IL-15 Augment HBV Therapeutic Vaccination and PD1 Blockade for Functional Cure In the AA...



IL-2 and IL-15 Augment HBV Therapeutic Vaccination and PD1 Blockade for Functional Cure In the AAV-HBV Mouse Model  Frontiers

Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic AU-007 in Melanoma ...



Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic AU-007 in Melanoma at AACR Annual Meeting  BioSpace

mRNA vaccine-induced SARS-CoV-2 spike-specific IFN-γ and IL-2 T-cell responses are predictive of ...



mRNA vaccine-induced SARS-CoV-2 spike-specific IFN-γ and IL-2 T-cell responses are predictive of serological neutralization and are transiently enhanced by pre-existing cross-reactive immunity  ASM Journals

The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment...



The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment of inflammatory skin diseases: two randomized, double-blind, placebo-controlled phase 1b trials  Nature

AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enh...



AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enhanced anti-tumor immunity and diminished toxicity  Frontiers

Coya touts partnership potential as IL-2 prospect comes through small Alzheimer's study - Fierce ...



Coya touts partnership potential as IL-2 prospect comes through small Alzheimer's study  Fierce Biotech

Teva's Breakthrough Cancer Immunotherapy Gains Momentum with Major Asian Market Partnership - Sto...



Teva's Breakthrough Cancer Immunotherapy Gains Momentum with Major Asian Market Partnership  Stock Titan

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T ...



Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation  Nature

Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complicatio...



Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease | mBio  ASM Journals

Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs - MyStateline



Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs  MyStateline

IL-2 Sturmovik Flying Circus Vol. IV Released - FSElite



IL-2 Sturmovik Flying Circus Vol. IV Released  FSElite

IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers



IL-2 based cancer immunotherapies: an evolving paradigm  Frontiers

Low-dose interleukin-2 added to standard ALS treatment extends patient survival, clinical trial f...



Low-dose interleukin-2 added to standard ALS treatment extends patient survival, clinical trial finds  Medical Xpress

Low-dose IL-2 promising in bullous pemphigoid treatment - Healio



Low-dose IL-2 promising in bullous pemphigoid treatment  Healio

BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Can...



BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Cancer  UroToday

Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection - Nature



Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection  Nature

Synthekine Presents Positive Initial Results from Phase 1 Clinical Trial of CD19 CAR-T (SYNCAR-00...



Synthekine Presents Positive Initial Results from Phase 1 Clinical Trial of CD19 CAR-T (SYNCAR-001) and Orthogonal IL-2 (STK-009) Combination Therapy for Treatment of Hematologic Malignancies at ASH 2024 Annual Meeting  Business Wire

A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus:...



A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus: Mechanisms, Efficacy, and Clinical Applications  Cureus

Case report: Low-dose interleukin-2: a treatment of bullous pemphigoid with predominantly perifol...



Case report: Low-dose interleukin-2: a treatment of bullous pemphigoid with predominantly perifollicular blistering caused by PD-1/PD-L1 inhibitor  Frontiers

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation - Science...



Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation  ScienceDirect.com

Engineered IL-2 molecule shows promise in treating autoimmune disease - McGill University



Engineered IL-2 molecule shows promise in treating autoimmune disease  McGill University

IL-2R structure and signaling. The IL-2 receptor (IL-2R) has three... - researchgate.net



IL-2R structure and signaling. The IL-2 receptor (IL-2R) has three...  researchgate.net

Stratum Corneum Interleukin-2 in Facial Eczema at 1-Month-Old Predicts Later Atopic Dermatitis - ...



Stratum Corneum Interleukin-2 in Facial Eczema at 1-Month-Old Predicts Later Atopic Dermatitis  Wiley Online Library

Dr Tarhini on the Combination of High-Dose Bolus IL-2 and CTLA-4 Inhibition in Advanced Melanoma ...



Dr Tarhini on the Combination of High-Dose Bolus IL-2 and CTLA-4 Inhibition in Advanced Melanoma  OncLive

flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface me...



flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane  Nature

Redirecting immune signaling with cytokine adaptors - Nature



Redirecting immune signaling with cytokine adaptors  Nature

Breakthrough: New GLP-1/IL-2 Combo Drug Outperforms Standard Therapy by 42% in Alzheimer's Resear...



Breakthrough: New GLP-1/IL-2 Combo Drug Outperforms Standard Therapy by 42% in Alzheimer's Research  Stock Titan

Fig. 4. IL-2-induced T cell proliferation in the presence of high-dose... - researchgate.net



Fig. 4. IL-2-induced T cell proliferation in the presence of high-dose...  researchgate.net

Fig. 2. 4H3MC inhibits IL-2 production in activated T cells. (A) Jurkat... - researchgate.net



Fig. 2. 4H3MC inhibits IL-2 production in activated T cells. (A) Jurkat...  researchgate.net

Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in pat...



Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in patients with ACS: The results of the IVORY trial and IVORY FINALE study  American Heart Association Journals

(PDF) Refractory Behçet’s disease treated with low-dose interleukin-2: A case report - researchga...



(PDF) Refractory Behçet’s disease treated with low-dose interleukin-2: A case report  researchgate.net

IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL - MedPage Today



IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL  MedPage Today

FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow... - researchgate.net



FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow...  researchgate.net

SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce ...



SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce more IL-2  Frontiers

IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. t...



IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages  Frontiers

The Presence and Pathogenic Roles of M(IL-33 + IL-2) Macrophages in Allergic Airway Inflammation ...



The Presence and Pathogenic Roles of M(IL-33 + IL-2) Macrophages in Allergic Airway Inflammation  Wiley Online Library

Fig. 1. Interleukin-2 takes center stage. The different functional... - researchgate.net



Fig. 1. Interleukin-2 takes center stage. The different functional...  researchgate.net

FIG. 4. Increased IL-2 production and T-cell proliferation in... - researchgate.net



FIG. 4. Increased IL-2 production and T-cell proliferation in...  researchgate.net

Dual role of IL-2 signaling mediated by different IL-2 receptor... - researchgate.net



Dual role of IL-2 signaling mediated by different IL-2 receptor...  researchgate.net

10-Day Weather Forecast for Chicago, IL - The Weather Channel | weather.com - The Weather Channel



10-Day Weather Forecast for Chicago, IL - The Weather Channel | weather.com  The Weather Channel

Jurkat cell line responses for Th1/pro-inflammatory (IL-2 and IL-17)... - researchgate.net



Jurkat cell line responses for Th1/pro-inflammatory (IL-2 and IL-17)...  researchgate.net

Figure 4. IL-2-REH selectively promotes signaling in Tregs with reduced... - researchgate.net



Figure 4. IL-2-REH selectively promotes signaling in Tregs with reduced...  researchgate.net

Fig. 2. Increases in Tregs after single dose in vivo IL-2 treatments.... - researchgate.net



Fig. 2. Increases in Tregs after single dose in vivo IL-2 treatments....  researchgate.net

Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen - Front...



Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen  Frontiers

FIGURE 5. IL-2 secretion is required for enhanced STAT5 activation and... - researchgate.net



FIGURE 5. IL-2 secretion is required for enhanced STAT5 activation and...  researchgate.net

Fig. 3. Validation of IL-2 activation in gluten-induced recall... - researchgate.net



Fig. 3. Validation of IL-2 activation in gluten-induced recall...  researchgate.net

Figure 4. In vitro NK proliferation (A) IL-2 consumption by T cells was... - researchgate.net



Figure 4. In vitro NK proliferation (A) IL-2 consumption by T cells was...  researchgate.net

Figure 3. In vitro proliferation and expansion of NK cells by MBP IL-2... - researchgate.net



Figure 3. In vitro proliferation and expansion of NK cells by MBP IL-2...  researchgate.net

From the bottom of a lake, a Russian plane lands at the Smithsonian - The Washington Post



From the bottom of a lake, a Russian plane lands at the Smithsonian  The Washington Post

IL-2 Korea Announcement - FSElite



IL-2 Korea Announcement  FSElite

Novel technique may provide ‘incredible’ benefit to CAR T-cell therapy - Healio



Novel technique may provide ‘incredible’ benefit to CAR T-cell therapy  Healio

Figure 1: IL-2 signals program CD8+ T cells for secondary population... - researchgate.net



Figure 1: IL-2 signals program CD8+ T cells for secondary population...  researchgate.net

The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity ...



The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity  Wiley Online Library

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective...



IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein  Science | AAAS

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JC...



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI.org

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature



PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function  Nature

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature



PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program  Nature

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective...



IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein  Science | AAAS

IL-2 Signaling Axis Defects: How Many Faces? - Frontiers



IL-2 Signaling Axis Defects: How Many Faces?  Frontiers

Signaling through IL-2 receptor (IL-2R) pathway. IL-2 exerts its... - researchgate.net



Signaling through IL-2 receptor (IL-2R) pathway. IL-2 exerts its...  researchgate.net

Selective delivery of low-affinity IL-2 to PD-1+ T cells rejuvenates antitumor immunity with redu...



Selective delivery of low-affinity IL-2 to PD-1+ T cells rejuvenates antitumor immunity with reduced toxicity  JCI.org

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor ...



Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor  PNAS