"IL-2" の関連情報検索結果

Effects of 6-week olanzapine treatment on serum IL-2, IL-4, IL-8, IL-10, and TNF-α levels in drug...



Effects of 6-week olanzapine treatment on serum IL-2, IL-4, IL-8, IL-10, and TNF-α levels in drug-naive individuals with first-episode schizophrenia  BMC Psychiatry

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...



Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective and emerging trends  Nature.com

IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. t...



IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages  Frontiers

Low-dose IL-2 promising in bullous pemphigoid treatment - Healio



Low-dose IL-2 promising in bullous pemphigoid treatment  Healio

Groundbreaking cancer treatment destroys advanced-stage tumors in less than 6 days - The Brighter...



Groundbreaking cancer treatment destroys advanced-stage tumors in less than 6 days  The Brighter Side of News

BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Can...



BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Cancer  UroToday

IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL - Medpage Today



IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL  Medpage Today

Dr Tarhini on the Combination of High-Dose Bolus IL-2 and CTLA-4 Inhibition in Advanced Melanoma ...



Dr Tarhini on the Combination of High-Dose Bolus IL-2 and CTLA-4 Inhibition in Advanced Melanoma  OncLive

Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs - MyStateline.com



Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs  MyStateline.com

Targeting systemic IL-2 to BCMA CAR-T cells - Nature.com



Targeting systemic IL-2 to BCMA CAR-T cells  Nature.com

IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers



IL-2 based cancer immunotherapies: an evolving paradigm  Frontiers

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature.com



PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function  Nature.com

The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer - Nature.com



The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer  Nature.com

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...



T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics  Nature.com

A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T ...



A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cells  Nature.com

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T - Nature.com



Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T  Nature.com

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T ...



Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation  Nature.com

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue...



Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue  Nature.com

A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism - Nat...



A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism  Nature.com

flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface me...



flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane  Nature.com

AACR: Synthekine hopes new IL-2 will be the high-alpha in a beta class - Fierce Biotech



AACR: Synthekine hopes new IL-2 will be the high-alpha in a beta class  Fierce Biotech

Interleukin-2 is required for NKp30-dependent NK cell cytotoxicity by preferentially regulating N...



Interleukin-2 is required for NKp30-dependent NK cell cytotoxicity by preferentially regulating NKp30 expression  Frontiers

Innovent braves bruising cytokine space, linking fusion protein to tumor responses in small study...



Innovent braves bruising cytokine space, linking fusion protein to tumor responses in small study  Fierce Biotech

Revealing the significance of IL-2 and IL-5 in SARS-CoV-2-specific T-cell responses in kidney tra...



Revealing the significance of IL-2 and IL-5 in SARS-CoV-2-specific T-cell responses in kidney transplant recipients  Nature.com

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 - Na...



Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2  Nature.com

CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus - Science



CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus  Science

Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using ...



Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins  Frontiers

Anti-cancer Therapies Employing IL-2 Cytokine Tumor Targeting: Contribution of Innate, Adaptive a...



Anti-cancer Therapies Employing IL-2 Cytokine Tumor Targeting: Contribution of Innate, Adaptive and Immunosuppressive Cells in the Anti-tumor Efficacy  Frontiers

The Potential of Harnessing IL-2-Mediated Immunosuppression to Prevent Pathogenic B Cell Response...



The Potential of Harnessing IL-2-Mediated Immunosuppression to Prevent Pathogenic B Cell Responses  Frontiers

Oncolytic Adenovirus Coding for a Variant Interleukin 2 (vIL-2) Cytokine Re-Programs the Tumor Mi...



Oncolytic Adenovirus Coding for a Variant Interleukin 2 (vIL-2) Cytokine Re-Programs the Tumor Microenvironment and Confers Enhanced Tumor Control  Frontiers

Korea IL-2 Series Brings The Military Flight Sim To PC VR Next Year - UploadVR



Korea IL-2 Series Brings The Military Flight Sim To PC VR Next Year  UploadVR

From the bottom of a lake, a Russian plane lands at the Smithsonian - The Washington Post



From the bottom of a lake, a Russian plane lands at the Smithsonian  The Washington Post

Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic Antibody, AU-007, a...



Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic Antibody, AU-007, at 39th Society for Immunotherapy of Cancer (SITC) Annual Meeting  Business Wire

Better Identification of Cognitive Decline With Interleukin-2 Than With Amyloid and Tau Protein B...



Better Identification of Cognitive Decline With Interleukin-2 Than With Amyloid and Tau Protein Biomarkers in Amnestic Mild Cognitive Impairment  Frontiers

Overcoming toxicities: are IL-2 smart cytokines the next big thing? - Labiotech.eu



Overcoming toxicities: are IL-2 smart cytokines the next big thing?  Labiotech.eu

Novel IL-2 Agent Shows Promise in Advanced Solid Tumors - Medpage Today



Novel IL-2 Agent Shows Promise in Advanced Solid Tumors  Medpage Today

Harnessing IGF-1 and IL-2 as biomarkers for calcineurin activity to tailor optimal FK506 dosage i...



Harnessing IGF-1 and IL-2 as biomarkers for calcineurin activity to tailor optimal FK506 dosage in α-synucleinopathies  Frontiers

Concomitant use of interleukin-2 and tacrolimus suppresses follicular helper T cell proportion an...



Concomitant use of interleukin-2 and tacrolimus suppresses follicular helper T cell proportion and exerts therapeutic effect against lupus nephritis in systemic lupus erythematosus-like chronic graft versus host disease  Frontiers

IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimula...



IL-2 Restores T-Cell Dysfunction Induced by Persistent Mycobacterium tuberculosis Antigen Stimulation  Frontiers

Dr Tarhini on Hogh-Dose Bolus IL-2 With Ipilimumab Followed by Nivolumab in Melanoma - OncLive



Dr Tarhini on Hogh-Dose Bolus IL-2 With Ipilimumab Followed by Nivolumab in Melanoma  OncLive

A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus:...



A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus: Mechanisms, Efficacy, and Clinical Applications  Cureus

Restoration of the Smithsonian’s Ilyushin Il-2 Shturmovik - Vintage Aviation News



Restoration of the Smithsonian’s Ilyushin Il-2 Shturmovik  Vintage Aviation News

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JCI



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI

Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model - Frontiers



Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model  Frontiers

IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjö...



IL-2 Inhibition of Th17 Generation Rather Than Induction of Treg Cells Is Impaired in Primary Sjögren’s Syndrome Patients  Frontiers

IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation - Al‐Aghba...



IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation - Al‐Aghbar - 2024 - Immunology  Wiley Online Library

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JCI



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI

IL-2 Korea Announcement - FSElite



IL-2 Korea Announcement  FSElite

Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome -...



Case Report: Interleukin-2 Receptor Common Gamma Chain Defect Presented as a Hyper-IgE Syndrome  Frontiers

SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce ...



SARS-CoV-2 spike protein induces the cytokine release syndrome by stimulating T cells to produce more IL-2  Frontiers

IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells - Frontiers



IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells  Frontiers

Ilyushin Il-2: 5 Fast Facts About The World’s Most Produced Warplane - Simple Flying



Ilyushin Il-2: 5 Fast Facts About The World’s Most Produced Warplane  Simple Flying

Lifileucel First Cellular Therapy Approved for Cancer - National Cancer Institute (.gov)



Lifileucel First Cellular Therapy Approved for Cancer  National Cancer Institute (.gov)

Engineered Cytokine Signaling to Improve CAR T Cell Effector Function - Frontiers



Engineered Cytokine Signaling to Improve CAR T Cell Effector Function  Frontiers

IL-2 Series To Produce New Game Based On The Korean War - Bleeding Cool News



IL-2 Series To Produce New Game Based On The Korean War  Bleeding Cool News

Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity - Na...



Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity  Nature.com

Recent patents in allergy and immunology: The interleukin-2 receptor pathway agonist rezpegaldesl...



Recent patents in allergy and immunology: The interleukin-2 receptor pathway agonist rezpegaldesleukin (REZPEG) for the rescue of regulatory T cells in chronic inflammatory and autoimmune diseases  Wiley Online Library

Increased TNF-α/IFN-γ/IL-2 and Decreased TNF-α/IFN-γ Production by Central Memory T Cells Are Ass...



Increased TNF-α/IFN-γ/IL-2 and Decreased TNF-α/IFN-γ Production by Central Memory T Cells Are Associated with Protective Responses against Bovine Tuberculosis Following BCG Vaccination  Frontiers

PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells - Nature.com



PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells  Nature.com

Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8+T cells for systemic anti...



Anti-PD-1 cis-delivery of low-affinity IL-12 activates intratumoral CD8+T cells for systemic antitumor responses  Nature.com

Developmental and Functional Control of Natural Killer Cells by Cytokines - Frontiers



Developmental and Functional Control of Natural Killer Cells by Cytokines  Frontiers

JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL...



JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans  Nature.com

Hugely popular IL-2 Sturmovik devs announce new combat flight sim for next year based on Korean W...



Hugely popular IL-2 Sturmovik devs announce new combat flight sim for next year based on Korean War  ReadWrite

Gilead pays $43.5M for early-phase IL-12 prospect from Xilio as biotech reduces head count - Fier...



Gilead pays $43.5M for early-phase IL-12 prospect from Xilio as biotech reduces head count  Fierce Biotech

Low-Zone IL-2 Signaling: Fusion Proteins Containing Linked CD25 and IL-2 Domains Sustain Toleroge...



Low-Zone IL-2 Signaling: Fusion Proteins Containing Linked CD25 and IL-2 Domains Sustain Tolerogenic Vaccination in vivo and Promote Dominance of FOXP3+ Tregs in vitro  Frontiers

New Strategy for Preventing Relapse After CAR T-Cell Therapy - Harvard Medical School



New Strategy for Preventing Relapse After CAR T-Cell Therapy  Harvard Medical School

Interleukin-2 Mediated Expansion of T-Regulatory Cells as an Ischemic Stroke Therapy - AHA Journals



Interleukin-2 Mediated Expansion of T-Regulatory Cells as an Ischemic Stroke Therapy  AHA Journals

Korea. IL-2 Series - Official Reveal Trailer - IGN



Korea. IL-2 Series - Official Reveal Trailer  IGN

IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite ...



IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers  ScienceDirect.com

All Eyes Are on IL-15 in Early Phase Studies - OncLive



All Eyes Are on IL-15 in Early Phase Studies  OncLive

Phenotype and Function of Activated Natural Killer Cells From Patients With Prostate Cancer: Pati...



Phenotype and Function of Activated Natural Killer Cells From Patients With Prostate Cancer: Patient-Dependent Responses to Priming and IL-2 Activation  Frontiers

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JCI



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JCI



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI

Spatial and functional targeting of intratumoral Tregs reverses CD8 - JCI



Spatial and functional targeting of intratumoral Tregs reverses CD8  JCI

To improve a promising cancer drug, cut it in half - UW Medicine Newsroom



To improve a promising cancer drug, cut it in half  UW Medicine Newsroom

Immunology - Merck



Immunology  Merck

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JCI



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI

IL-15 Upregulates Telomerase Expression and Potently Increases Proliferative Capacity of NK, NKT-...



IL-15 Upregulates Telomerase Expression and Potently Increases Proliferative Capacity of NK, NKT-Like, and CD8 T Cells  Frontiers

Soluble Interleukin-2 Receptor Predicts Treatment Outcome in Patients With Autoimmune Tubulointer...



Soluble Interleukin-2 Receptor Predicts Treatment Outcome in Patients With Autoimmune Tubulointerstitial Nephritis. A Preliminary Study  Frontiers

Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic...



Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic effects with anti-CTLA-4 therapy  Wiley Online Library

Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA ...



Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70  Science

Synthekine Announces Presentation of Initial Results from Phase 1a/1b Clinical Trial of STK-012 a...



Synthekine Announces Presentation of Initial Results from Phase 1a/1b Clinical Trial of STK-012 at AACR 2024 Annual Meeting  Business Wire

Sanofi pays Synthekine $40M to join preclinical push against vexing inflammatory target - Fierce ...



Sanofi pays Synthekine $40M to join preclinical push against vexing inflammatory target  Fierce Biotech

IL6 suppresses vaccine responses in neonates by enhancing IL2 activity on T follicular helper cel...



IL6 suppresses vaccine responses in neonates by enhancing IL2 activity on T follicular helper cells  Nature.com

IL-23 stabilizes an effector Treg cell program in the tumor microenvironment | Nature Immunology ...



IL-23 stabilizes an effector Treg cell program in the tumor microenvironment | Nature Immunology  Nature.com

Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives - ...



Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives  Journal of Translational Medicine

Smoking changes adaptive immunity with persistent effects - Nature.com



Smoking changes adaptive immunity with persistent effects  Nature.com

IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with pot...



IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity  Nature.com

New sights of low dose IL‐2: Restoration of immune homeostasis for viral infection - Su - 2024 - ...



New sights of low dose IL‐2: Restoration of immune homeostasis for viral infection - Su - 2024 - Immunology  Wiley Online Library

Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Cas...



Regulation of NK Cell Activation and Effector Functions by the IL-12 Family of Cytokines: The Case of IL-27  Frontiers

An engineered IL-2 partial agonist promotes CD8+ T cell stemness - Nature.com



An engineered IL-2 partial agonist promotes CD8+ T cell stemness  Nature.com

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothe...



Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells  pnas.org

Performance of serum soluble interleukin-2 receptor as a diagnostic marker for lymphoma in patien...



Performance of serum soluble interleukin-2 receptor as a diagnostic marker for lymphoma in patients with fever  Nature.com

Remodeling of T Cell Dynamics During Long COVID Is Dependent on Severity of SARS-CoV-2 Infection ...



Remodeling of T Cell Dynamics During Long COVID Is Dependent on Severity of SARS-CoV-2 Infection  Frontiers

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature.com



PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program  Nature.com

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy -...



A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy  Nature.com

Engineering IL-2 for immunotherapy of autoimmunity and cancer - Nature.com



Engineering IL-2 for immunotherapy of autoimmunity and cancer  Nature.com

IL-2 immunotherapy for targeting regulatory T cells in autoimmunity - Nature.com



IL-2 immunotherapy for targeting regulatory T cells in autoimmunity  Nature.com

2 Illinois Pizzerias Get Slice Of Fame On NYT National Roundup - Patch



2 Illinois Pizzerias Get Slice Of Fame On NYT National Roundup  Patch

PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiq...



PD-1 signaling negatively regulates the common cytokine receptor γ chain via MARCH5-mediated ubiquitination and degradation to suppress anti-tumor immunity | Cell Research  Nature.com