Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist - Nature

Facile induction of immune tolerance by an interleukin-2–TGFβ surrogate agonist  Nature

IL-2 and GLP-1 receptor agonist combination tackles neuroinflammation - Drug Target Review

IL-2 and GLP-1 receptor agonist combination tackles neuroinflammation  Drug Target Review

Aulos looks to Phase III for IL-2 mAb in NSCLC and melanoma - Clinical Trials Arena

Aulos looks to Phase III for IL-2 mAb in NSCLC and melanoma  Clinical Trials Arena

The role of IL-2 in type 2 immunity - Frontiers

The role of IL-2 in type 2 immunity  Frontiers

First-in-Class IL-2 Pathway Agonist Advances in AD - Dermatology Times

First-in-Class IL-2 Pathway Agonist Advances in AD  Dermatology Times

FDA Clears IND Application for Novel IL-2 Agent in Advanced NSCLC - CancerNetwork

FDA Clears IND Application for Novel IL-2 Agent in Advanced NSCLC  CancerNetwork

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial - FirstWor...

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial  FirstWord Pharma

Korea. IL-2 Series Reveals Post-Launch Content Roadmap - Bleeding Cool News

Korea. IL-2 Series Reveals Post-Launch Content Roadmap  Bleeding Cool News

PD-1 + IL-2 power couple: Wake up 'sleepy' T cells to turbo-charge cancer cures - EurekAlert!

PD-1 + IL-2 power couple: Wake up 'sleepy' T cells to turbo-charge cancer cures  EurekAlert!

Bispecific cytokine delivers for Innovent at last | ApexOnco - Clinical Trials news and analysis ...

Bispecific cytokine delivers for Innovent at last | ApexOnco - Clinical Trials news and analysis  Oncology Pipeline

Anti-inflammatory therapy with low-dose IL-2 in acute coronary syndromes: a randomized phase 2 tr...

Anti-inflammatory therapy with low-dose IL-2 in acute coronary syndromes: a randomized phase 2 trial  Nature

Novel IL-2 Therapy Combo Yields Initial Responses in Nonsquamous NSCLC - CancerNetwork

Novel IL-2 Therapy Combo Yields Initial Responses in Nonsquamous NSCLC  CancerNetwork

An immune competent in vitro model of IL2 induced vascular leakage enables mechanistic insights a...

An immune competent in vitro model of IL2 induced vascular leakage enables mechanistic insights and evaluation of mitigation strategies  Nature

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility ...

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models  Nature

Efficacy and safety of low-dose interleukin 2 for Behçet’s syndrome: a randomized, placebo-contro...

Efficacy and safety of low-dose interleukin 2 for Behçet’s syndrome: a randomized, placebo-controlled, double-blind, phase 2 clinical trial  Nature

IL2Pepscan: A machine learning framework for predicting IL-2 inducing peptides and their identifi...

IL2Pepscan: A machine learning framework for predicting IL-2 inducing peptides and their identification across global viral proteomes  Nature

Low-dose IL-2 therapy reduces arterial inflammation in acute coronary syndromes - Nature

Low-dose IL-2 therapy reduces arterial inflammation in acute coronary syndromes  Nature

In Silico tool for predicting, designing and scanning IL-2 inducing peptides | Scientific Reports...

In Silico tool for predicting, designing and scanning IL-2 inducing peptides | Scientific Reports  Nature

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion | Nature Com...

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion | Nature Communications  Nature

Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficac...

Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficacy in mouse autoimmune models  Nature

Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune respons...

Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response  Nature

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, dou...

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial  The Lancet

Biomineral tablets for long-acting IL-2 immunotherapy - Nature

Biomineral tablets for long-acting IL-2 immunotherapy  Nature

Adding low-dose IL-2 to riluzole may improve survival in ALS - ALS News Today

Adding low-dose IL-2 to riluzole may improve survival in ALS  ALS News Today

An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammat...

An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammatory CAR macrophages in renal cell carcinoma  Nature

CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducin...

CD2 targeted nanoparticles containing IL-2 mimic fetal-maternal tolerance of pregnancy by inducing synergistic TGF-β-producing NK cells and Tregs  Frontiers

1CGS Unveils Extended Support for Il-2 Sturmovik as Korea Hits Steam - DualShockers

1CGS Unveils Extended Support for Il-2 Sturmovik as Korea Hits Steam  DualShockers

Low-dose interleukin-2 for recurrent early pregnancy loss: a proof-of-concept study - medRxiv

Low-dose interleukin-2 for recurrent early pregnancy loss: a proof-of-concept study  medRxiv

PD-1 x IL-2 antibody fusions: The next Keytruda competitors? - BioCentury

PD-1 x IL-2 antibody fusions: The next Keytruda competitors?  BioCentury

Grateful Dead: Dave's Picks Volume 57 - Uptown Theatre, Chicago IL 2/1/78 (ALBUM REVIEW) - Glide ...

Grateful Dead: Dave's Picks Volume 57 - Uptown Theatre, Chicago IL 2/1/78 (ALBUM REVIEW)  Glide Magazine

1C Game Studios Presents "Korea. IL-2 Series" and Talks About the Future of the Series - IXBT.games

1C Game Studios Presents "Korea. IL-2 Series" and Talks About the Future of the Series  IXBT.games

New IL-2: Korea Gameplay Footage Released - FSElite

New IL-2: Korea Gameplay Footage Released  FSElite

Genetic Leap receives FDA IND clearance for first-in-class, oral natural IL-2 modulator - PR News...

Genetic Leap receives FDA IND clearance for first-in-class, oral natural IL-2 modulator  PR Newswire

9 biotechs making waves in interleukin therapeutics in 2025 - Labiotech.eu

9 biotechs making waves in interleukin therapeutics in 2025  Labiotech.eu

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals - ...

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals  Science | AAAS

PHOTOS: Erin LeCount – Chicago, IL – 2/5/2026 - Beyond The Stage Magazine

PHOTOS: Erin LeCount – Chicago, IL – 2/5/2026  Beyond The Stage Magazine

[ESMO 2025] GI Innovation’s IL-2 therapy shows tumor response in ICB-resistant cancers - koreabio...

[ESMO 2025] GI Innovation’s IL-2 therapy shows tumor response in ICB-resistant cancers  koreabiomed.com

Examining the evidence for IL-2 in amyotrophic lateral sclerosis - The Lancet

Examining the evidence for IL-2 in amyotrophic lateral sclerosis  The Lancet

Takeda pays Innovent $1.2B upfront, offers whopping $10B-plus in biobucks for cancer assets - Fie...

Takeda pays Innovent $1.2B upfront, offers whopping $10B-plus in biobucks for cancer assets  Fierce Biotech

Korea. IL-2 Series - Official Pre-Order Trailer - IGN

Korea. IL-2 Series - Official Pre-Order Trailer  IGN

Nektar touts 'deepening clinical effect' of IL-2 agonist in atopic dermatitis - FirstWord Pharma

Nektar touts 'deepening clinical effect' of IL-2 agonist in atopic dermatitis  FirstWord Pharma

FDA Clears IND for GL-IL2-138 in Cancer and Beyond - Targeted Oncology

FDA Clears IND for GL-IL2-138 in Cancer and Beyond  Targeted Oncology

Korea. IL-2 Series Releases New Gameplay Trailer - Bleeding Cool News

Korea. IL-2 Series Releases New Gameplay Trailer  Bleeding Cool News

Coya Therapeutics Announces Completion of Patient Enrollment of an Investigator-Initiated, Open-L...

Coya Therapeutics Announces Completion of Patient Enrollment of an Investigator-Initiated, Open-Label Study with Low-Dose IL-2 and CTLA4-Ig Combination Treatment in Patients with Mild to Moderate Frontotemporal Dementia  PR Newswire

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alter...

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alternatives  Fierce Biotech

New Flight Sim Wants You Broke To Get Above Minimum Spec - DualShockers

New Flight Sim Wants You Broke To Get Above Minimum Spec  DualShockers

Flight sim "Korea. IL-2 series" developers dived to the ground and showed local residents - IXBT....

Flight sim "Korea. IL-2 series" developers dived to the ground and showed local residents  IXBT.games

Interleukin-2 Inhibitors Clinical Trial Pipeline - GlobeNewswire

Interleukin-2 Inhibitors Clinical Trial Pipeline  GlobeNewswire

Cubs Place Catcher Miguel Amaya on the 10-day IL, 2 Days After Activating Him - FOX Sports

Cubs Place Catcher Miguel Amaya on the 10-day IL, 2 Days After Activating Him  FOX Sports

Low-dose interleukin-2 added to standard ALS treatment extends patient survival, clinical trial f...

Low-dose interleukin-2 added to standard ALS treatment extends patient survival, clinical trial finds  Medical Xpress

Coya Therapeutics Announces Results of Investigator-Initiated Study of LD IL-2 and CTLA4-Ig Demon...

Coya Therapeutics Announces Results of Investigator-Initiated Study of LD IL-2 and CTLA4-Ig Demonstrating Treg Enhancement and Cognitive Stability in Frontotemporal Dementia Patients  Business Wire

Korea. IL-2 Series - IGN France

Korea. IL-2 Series  IGN France

Mural hits a wall | ApexOnco - Clinical Trials news and analysis - Oncology Pipeline

Mural hits a wall | ApexOnco - Clinical Trials news and analysis  Oncology Pipeline

A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythemat...

A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythematosus  Frontiers

The Il-2 Sturmovik Wrecked Nazi Tanks - by David Axe - Trench Art | David Axe

The Il-2 Sturmovik Wrecked Nazi Tanks - by David Axe  Trench Art | David Axe

Topline atopic dermatitis data showcase IL-2 modulator’s ‘incredibly novel’ mechanism - Healio

Topline atopic dermatitis data showcase IL-2 modulator’s ‘incredibly novel’ mechanism  Healio

Korea. IL-2 Series - IGN India

Korea. IL-2 Series  IGN India

Creators of the "Korea. IL-2 Series" flight simulator showed the cockpit of the F-84E "Thunderjet...

Creators of the "Korea. IL-2 Series" flight simulator showed the cockpit of the F-84E "Thunderjet" - an aircraft with a complex history  IXBT.games

Authors of \"Korea. IL-2 Series\" Showed Graphics Settings, Interface, and Highly Detailed Map - ...

Authors of \"Korea. IL-2 Series\" Showed Graphics Settings, Interface, and Highly Detailed Map  IXBT.games

Medicenna Targets Pivotal 2026 as IL-2 Superkine Programs Advance Toward Registrational Trials - ...

Medicenna Targets Pivotal 2026 as IL-2 Superkine Programs Advance Toward Registrational Trials  TipRanks

IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers

IL-2 based cancer immunotherapies: an evolving paradigm  Frontiers

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits - Rockefeller U...

Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits  Rockefeller University Press

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function  Nature

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor ...

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor  PNAS

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective and emerging trends  Nature

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program  Nature

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People wi...

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People with Systemic Lupus Erythematosus  Lupus Foundation of America

Effects of interleukin-2 in immunostimulation and immunosuppression - Rockefeller University Press

Effects of interleukin-2 in immunostimulation and immunosuppression  Rockefeller University Press

Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and...

Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity  Nature

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism - Nature

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism  Nature

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells - Nature

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells  Nature

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue...

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue  Nature

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy -...

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy  Nature

CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communic...

CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communications  Nature

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulator...

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation  Nature

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 - Nature

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8  Nature

A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T ...

A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cells  Nature

Engineering IL-2 for immunotherapy of autoimmunity and cancer - Nature

Engineering IL-2 for immunotherapy of autoimmunity and cancer  Nature

Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulatio...

Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity  Nature

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 - Nature

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8  Nature

IL-2 treatment can be dangerous. How can drug firms tackle its challenges? - Chemical & Engineeri...

IL-2 treatment can be dangerous. How can drug firms tackle its challenges?  Chemical & Engineering News

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo ...

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells  Nature

Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates ...

Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8  Nature

An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer - Nature

An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer  Nature

Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist...

Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist  Nature

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 - Na...

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2  Nature

Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses - Frontiers

Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses  Frontiers

De novo design of potent and selective mimics of IL-2 and IL-15 - Nature

De novo design of potent and selective mimics of IL-2 and IL-15  Nature

Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity - Nature

Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity  Nature

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics  Nature

Managing Toxicities of High-Dose Interleukin-2 - CancerNetwork

Managing Toxicities of High-Dose Interleukin-2  CancerNetwork

Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using ...

Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins  Frontiers

A promising option for unremitting ulcerative colitis: Low-dose IL-2 - Boston Children's Answers

A promising option for unremitting ulcerative colitis: Low-dose IL-2  Boston Children's Answers

A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in...

A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia  Science | AAAS

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active f...

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis  Neurology® Journals

An engineered IL-2 partial agonist promotes CD8+ T cell stemness - Nature

An engineered IL-2 partial agonist promotes CD8+ T cell stemness  Nature

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helpe...

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells  Science | AAAS

Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma - OncLive

Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma  OncLive

Overcoming toxicities: are IL-2 smart cytokines the next big thing? - Labiotech.eu

Overcoming toxicities: are IL-2 smart cytokines the next big thing?  Labiotech.eu

Low-Dose Interleukin-2 Reduces Proinflammatory Biomarkers in Phase 2 Study of Alzheimer Disease -...

Low-Dose Interleukin-2 Reduces Proinflammatory Biomarkers in Phase 2 Study of Alzheimer Disease  Neurology Live