Is a New Super Mario Bros Collection Coming to Switch 2? - VICE

Is a New Super Mario Bros Collection Coming to Switch 2?  VICE

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B -...

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B  Nature

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Editorial - Nintendo World Re...

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Editorial  Nintendo World Report

Fluorescent fusion protein knockout mediated by anti-GFP nanobody - Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody  Nature

G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs - Nature

G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs  Nature

NSMB’s 30th anniversary: shining a light on the invisible - Nature

NSMB’s 30th anniversary: shining a light on the invisible  Nature

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV - Nature

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV  Nature

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transpor...

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain  Nature

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion trans...

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport  Nature

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational foldin...

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding  Nature

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins - Nature

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins  Nature

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiatio...

The dynamic interactome and genomic targets of Polycomb complexes during stem-cell differentiation  Nature

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit...

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit  Nature

The role of lipids in mechanosensation - Nature

The role of lipids in mechanosensation  Nature

The pol II CTD: new twists in the tail - Nature

The pol II CTD: new twists in the tail  Nature

New insights into ubiquitin E3 ligase mechanism - Nature

New insights into ubiquitin E3 ligase mechanism  Nature

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40 ...

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40  Nature

Crystal structure of the MOP flippase MurJ in an inward-facing conformation - Nature

Crystal structure of the MOP flippase MurJ in an inward-facing conformation  Nature

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex -...

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex  Nature

Structure and assembly of the NOT module of the human CCR4–NOT complex - Nature

Structure and assembly of the NOT module of the human CCR4–NOT complex  Nature

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ - Nature

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ  Nature

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation - Na...

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation  Nature

Detecting endogenous SUMO targets in mammalian cells and tissues - Nature

Detecting endogenous SUMO targets in mammalian cells and tissues  Nature

The evolutionary journey of Argonaute proteins - Nature

The evolutionary journey of Argonaute proteins  Nature

A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal fu...

A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function  Nature

7SK-BAF axis controls pervasive transcription at enhancers - Nature

7SK-BAF axis controls pervasive transcription at enhancers  Nature

DNA methylation dynamics in health and disease - Nature

DNA methylation dynamics in health and disease  Nature

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex - Nature

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex  Nature

'New Super Mario Bros. U Deluxe' is the best game I've ever despised - Mashable

'New Super Mario Bros. U Deluxe' is the best game I've ever despised  Mashable

Post-translational modifications in signal integration - Nature

Post-translational modifications in signal integration  Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase - Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase  Nature

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43 - Nature

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43  Nature

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells - Nature

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells  Nature

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact ...

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT  Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA - Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA  Nature

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin...

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains  Nature

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle - Nature

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle  Nature

Conserved mRNA-binding proteomes in eukaryotic organisms - Nature

Conserved mRNA-binding proteomes in eukaryotic organisms  Nature

Crystal structure of a monomeric retroviral protease solved by protein folding game players - Nature

Crystal structure of a monomeric retroviral protease solved by protein folding game players  Nature

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's ...

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease  Nature

Structural basis for bifunctional peptide recognition at human δ-opioid receptor - Nature

Structural basis for bifunctional peptide recognition at human δ-opioid receptor  Nature

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation - Nature

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation  Nature

Histone propionylation is a mark of active chromatin - Nature

Histone propionylation is a mark of active chromatin  Nature

New Super Mario Bros. U Hands-on Preview - Hands-on Preview - Nintendo World Report

New Super Mario Bros. U Hands-on Preview - Hands-on Preview  Nintendo World Report

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase - Nature

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase  Nature

Structural basis of the specificity of USP18 toward ISG15 - Nature

Structural basis of the specificity of USP18 toward ISG15  Nature

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation ...

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation  Nature

The RNA-binding protein repertoire of embryonic stem cells - Nature

The RNA-binding protein repertoire of embryonic stem cells  Nature

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiatio...

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation  Nature

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism - Nature

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism  Nature

53BP1 fosters fidelity of homology-directed DNA repair - Nature

53BP1 fosters fidelity of homology-directed DNA repair  Nature

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation...

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation  Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1 - Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1  Nature

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotei...

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I  Nature

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin o...

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers  Nature

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa - Nature

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa  Nature

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state - Nature

A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state  Nature

Structures of the human mitochondrial ribosome in native states of assembly - Nature

Structures of the human mitochondrial ribosome in native states of assembly  Nature

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made protei...

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies  Nature

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cy...

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling  Nature

Structural basis for regulation of Arp2/3 complex by GMF - Nature

Structural basis for regulation of Arp2/3 complex by GMF  Nature

Perceiving the epigenetic landscape through histone readers - Nature

Perceiving the epigenetic landscape through histone readers  Nature

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specific...

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity  Nature

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to tha...

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs  Nature

Sequence composition of disordered regions fine-tunes protein half-life - Nature

Sequence composition of disordered regions fine-tunes protein half-life  Nature

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem ...

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells  Nature

Structural determinants of integrin β-subunit specificity for latent TGF-β - Nature

Structural determinants of integrin β-subunit specificity for latent TGF-β  Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease - Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease  Nature

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange ...

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange  Nature

A 3D cellular context for the macromolecular world - Nature

A 3D cellular context for the macromolecular world  Nature

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1 - Nature

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1  Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly - Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly  Nature

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A ...

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses  Nature

-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics - Nature

-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics  Nature

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity - Na...

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity  Nature

Structural basis of the proinflammatory signaling complex mediated by TSLP - Nature

Structural basis of the proinflammatory signaling complex mediated by TSLP  Nature

A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding ...

A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding  Nature

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteas...

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome  Nature

Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosacc...

Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase  Nature

Katanin spiral and ring structures shed light on power stroke for microtubule severing - Nature

Katanin spiral and ring structures shed light on power stroke for microtubule severing  Nature

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate - Nature

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate  Nature

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhanc...

Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors  Nature

An interactive environment for agile analysis and visualization of ChIP-sequencing data - Nature

An interactive environment for agile analysis and visualization of ChIP-sequencing data  Nature

DNA–RNA hybrids: the risks of DNA breakage during transcription - Nature

DNA–RNA hybrids: the risks of DNA breakage during transcription  Nature

Position effects influence HIV latency reversal - Nature

Position effects influence HIV latency reversal  Nature

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid clie...

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client  Nature

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution - N...

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution  Nature

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation - N...

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation  Nature

The structural basis of direct glucocorticoid-mediated transrepression - Nature

The structural basis of direct glucocorticoid-mediated transrepression  Nature

Nonsense-mediated mRNA decay (NMD) mechanisms - Nature

Nonsense-mediated mRNA decay (NMD) mechanisms  Nature

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specifici...

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity  Nature

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges - ...

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges  Nature

Functional implications of genome topology - Nature

Functional implications of genome topology  Nature

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1 - Nature

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1  Nature

Structural basis for membrane targeting of the BBSome by ARL6 - Nature

Structural basis for membrane targeting of the BBSome by ARL6  Nature

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo - Nature

Large-scale mapping of branchpoints in human pre-mRNA transcripts in vivo  Nature

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis w...

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer  Nature

Transcriptional regulation by Polycomb group proteins - Nature

Transcriptional regulation by Polycomb group proteins  Nature

Structure and VP16 binding of the Mediator Med25 activator interaction domain - Nature

Structure and VP16 binding of the Mediator Med25 activator interaction domain  Nature

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA - Nature

Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA  Nature