Is a New Super Mario Bros Collection Coming to Switch 2? - VICE

Is a New Super Mario Bros Collection Coming to Switch 2?  VICE

NSMB’s 30th anniversary: shining a light on the invisible - Nature

NSMB’s 30th anniversary: shining a light on the invisible  Nature

New Super Mario Bros.™ U Deluxe - nintendo.com

New Super Mario Bros.™ U Deluxe  nintendo.com

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Nintendo World Report

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels  Nintendo World Report

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation - Nature

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation  Nature

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem ...

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells  Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody - Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody  Nature

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome...

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis  Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis - Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis  Nature

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway - Nature

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway  Nature

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site - Nature

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site  Nature

Detecting endogenous SUMO targets in mammalian cells and tissues - Nature

Detecting endogenous SUMO targets in mammalian cells and tissues  Nature

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers - Nature

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers  Nature

The evolutionary journey of Argonaute proteins - Nature

The evolutionary journey of Argonaute proteins  Nature

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A ...

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses  Nature

Transcriptional regulation by Polycomb group proteins - Nature

Transcriptional regulation by Polycomb group proteins  Nature

Post-translational modifications in signal integration - Nature

Post-translational modifications in signal integration  Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein - Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein  Nature

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin main...

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance  Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD - Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD  Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly - Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly  Nature

Structural basis of enzyme encapsulation into a bacterial nanocompartment - Nature

Structural basis of enzyme encapsulation into a bacterial nanocompartment  Nature

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2 - Nature

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2  Nature

Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1 - Nature

Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1  Nature

'New Super Mario Bros. U Deluxe' is the best game I've ever despised - Mashable

'New Super Mario Bros. U Deluxe' is the best game I've ever despised  Mashable

Promiscuous RNA binding by Polycomb repressive complex 2 - Nature

Promiscuous RNA binding by Polycomb repressive complex 2  Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway - Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway  Nature

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain - Nature

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain  Nature

The program for processing newly synthesized histones H3.1 and H4 - Nature

The program for processing newly synthesized histones H3.1 and H4  Nature

Superwobbling facilitates translation with reduced tRNA sets - Nature

Superwobbling facilitates translation with reduced tRNA sets  Nature

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cel...

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells  Nature

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression - Nature

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression  Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins - Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins  Nature

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation - Na...

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation  Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1 - Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1  Nature

Replication stress: getting back on track - Nature

Replication stress: getting back on track  Nature

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made protei...

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies  Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin - Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin  Nature

Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases - Nature

Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases  Nature

Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune resp...

Regulator-dependent mechanisms of C3b processing by factor I allow differentiation of immune responses  Nature

Phosphorylation-dependent activity of the deubiquitinase DUBA - Nature

Phosphorylation-dependent activity of the deubiquitinase DUBA  Nature

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres - Na...

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres  Nature

Existence of a microRNA pathway in anucleate platelets - Nature

Existence of a microRNA pathway in anucleate platelets  Nature

Structural basis for the activation of PPARγ by oxidized fatty acids - Nature

Structural basis for the activation of PPARγ by oxidized fatty acids  Nature

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induce...

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization  Nature

High-resolution structure of the Escherichia coli ribosome - Nature

High-resolution structure of the Escherichia coli ribosome  Nature

NMR Exchange Format: a unified and open standard for representation of NMR restraint data - Nature

NMR Exchange Format: a unified and open standard for representation of NMR restraint data  Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease - Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease  Nature

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex forma...

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex formation  Nature

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases - Nature

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases  Nature

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation ...

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing  Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding - Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding  Nature

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP - Nature

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP  Nature

New Super Mario Bros. U Hands-on Preview - Hands-on Preview - Nintendo World Report

New Super Mario Bros. U Hands-on Preview - Hands-on Preview  Nintendo World Report

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 pro...

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins  Nature

A rule of seven in Watson-Crick base-pairing of mismatched sequences - Nature

A rule of seven in Watson-Crick base-pairing of mismatched sequences  Nature

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization...

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization  Nature

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells - Nature

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells  Nature

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules - ...

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules  Nature

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2 - ...

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2  Nature

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfe...

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer  Nature

Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo ...

Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo  Nature

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A - Nature

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A  Nature

A novel actin binding site of myosin required for effective muscle contraction - Nature

A novel actin binding site of myosin required for effective muscle contraction  Nature

Determinants of nucleosome positioning - Nature

Determinants of nucleosome positioning  Nature

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activatio...

Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation  Nature

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mecha...

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism  Nature

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution - Nature

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution  Nature

The structural basis of direct glucocorticoid-mediated transrepression - Nature

The structural basis of direct glucocorticoid-mediated transrepression  Nature

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasome...

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes  Nature

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments - Nature

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments  Nature

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macroc...

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain  Nature

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubuli...

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin  Nature

Privateer: software for the conformational validation of carbohydrate structures - Nature

Privateer: software for the conformational validation of carbohydrate structures  Nature

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant...

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant  Nature

Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S...

Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit  Nature

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription comp...

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes  Nature

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex form...

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation  Nature

A complex network of factors with overlapping affinities represses splicing through intronic elem...

A complex network of factors with overlapping affinities represses splicing through intronic elements  Nature

Synaptic vesicle fusion - Nature

Synaptic vesicle fusion  Nature

Say it with proteins: an alphabet of crystal structures - Nature

Say it with proteins: an alphabet of crystal structures  Nature

Modulation of protein properties in living cells using nanobodies - Nature

Modulation of protein properties in living cells using nanobodies  Nature

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human geno...

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome  Nature

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA - Nature

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA  Nature

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4 - Nature

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4  Nature

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev - Nature

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev  Nature

Structural basis of respiratory syncytial virus neutralization by motavizumab - Nature

Structural basis of respiratory syncytial virus neutralization by motavizumab  Nature

Bimodal expression of PHO84 is modulated by early termination of antisense transcription - Nature

Bimodal expression of PHO84 is modulated by early termination of antisense transcription  Nature

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes - Nature

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes  Nature

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction -...

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction  Nature

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair - Nature

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair  Nature

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mou...

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells  Nature

The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila mela...

The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome  Nature

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair - Nature

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair  Nature

Mechanism of potassium-channel selectivity revealed by Na - Nature

Mechanism of potassium-channel selectivity revealed by Na  Nature

Molecular organization of the COG vesicle tethering complex - Nature

Molecular organization of the COG vesicle tethering complex  Nature

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 - Nature

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2  Nature

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by th...

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne  Nature

PTEN is a protein tyrosine phosphatase for IRS1 - Nature

PTEN is a protein tyrosine phosphatase for IRS1  Nature

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylat...

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation  Nature