Is a New Super Mario Bros Collection Coming to Switch 2? - VICE

Is a New Super Mario Bros Collection Coming to Switch 2?  VICE

New Super Mario Bros. U Deluxe: All of the secret exits and world skips - Digital Trends

New Super Mario Bros. U Deluxe: All of the secret exits and world skips  Digital Trends

NSMB’s 30th anniversary: shining a light on the invisible - Nature

NSMB’s 30th anniversary: shining a light on the invisible  Nature

New Super Mario Bros.™ U Deluxe - nintendo.com

New Super Mario Bros.™ U Deluxe  nintendo.com

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Nintendo World Report

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels  Nintendo World Report

Fluorescent fusion protein knockout mediated by anti-GFP nanobody - Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody  Nature

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation - Nature

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation  Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis - Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis  Nature

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway - Nature

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway  Nature

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome...

Stage-specific assembly events of the 6-MDa small-subunit processome initiate eukaryotic ribosome biogenesis  Nature

Detecting endogenous SUMO targets in mammalian cells and tissues - Nature

Detecting endogenous SUMO targets in mammalian cells and tissues  Nature

The evolutionary journey of Argonaute proteins - Nature

The evolutionary journey of Argonaute proteins  Nature

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A ...

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses  Nature

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers - Nature

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers  Nature

Transcriptional regulation by Polycomb group proteins - Nature

Transcriptional regulation by Polycomb group proteins  Nature

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 b...

Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA  Nature

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation ...

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation  Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase - Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase  Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD - Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD  Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA - Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA  Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein - Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein  Nature

Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1 - Nature

Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1  Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly - Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly  Nature

Promiscuous RNA binding by Polycomb repressive complex 2 - Nature

Promiscuous RNA binding by Polycomb repressive complex 2  Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway - Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway  Nature

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 -...

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120  Nature

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2 - Nature

Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2  Nature

New Super Mario Bros. U Hands-on Preview - Hands-on Preview - Nintendo World Report

New Super Mario Bros. U Hands-on Preview - Hands-on Preview  Nintendo World Report

Structural basis of enzyme encapsulation into a bacterial nanocompartment - Nature

Structural basis of enzyme encapsulation into a bacterial nanocompartment  Nature

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cel...

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells  Nature

Molecular chaperones: providing a safe place to weather a midlife protein-folding crisis - Nature

Molecular chaperones: providing a safe place to weather a midlife protein-folding crisis  Nature

Superwobbling facilitates translation with reduced tRNA sets - Nature

Superwobbling facilitates translation with reduced tRNA sets  Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins - Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins  Nature

Replication stress: getting back on track - Nature

Replication stress: getting back on track  Nature

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin o...

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers  Nature

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression - Nature

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression  Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin - Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin  Nature

DNA methylation dynamics in health and disease - Nature

DNA methylation dynamics in health and disease  Nature

Structural basis for the activation of PPARγ by oxidized fatty acids - Nature

Structural basis for the activation of PPARγ by oxidized fatty acids  Nature

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP - Nature

Mechanism of activation of bacterial cellulose synthase by cyclic di-GMP  Nature

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made protei...

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies  Nature

Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases - Nature

Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases  Nature

Existence of a microRNA pathway in anucleate platelets - Nature

Existence of a microRNA pathway in anucleate platelets  Nature

High-resolution structure of the Escherichia coli ribosome - Nature

High-resolution structure of the Escherichia coli ribosome  Nature

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induce...

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization  Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease - Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease  Nature

NMR Exchange Format: a unified and open standard for representation of NMR restraint data - Nature

NMR Exchange Format: a unified and open standard for representation of NMR restraint data  Nature

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization...

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization  Nature

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules - ...

More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules  Nature

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing m...

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs  Nature

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site - Nature

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site  Nature

A rule of seven in Watson-Crick base-pairing of mismatched sequences - Nature

A rule of seven in Watson-Crick base-pairing of mismatched sequences  Nature

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain - Nature

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain  Nature

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres - Na...

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres  Nature

New Super Mario Bros. 2 review for 3DS - Gaming Age

New Super Mario Bros. 2 review for 3DS  Gaming Age

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases - Nature

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases  Nature

A novel actin binding site of myosin required for effective muscle contraction - Nature

A novel actin binding site of myosin required for effective muscle contraction  Nature

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 pro...

Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins  Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding - Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding  Nature

Functional implications of genome topology - Nature

Functional implications of genome topology  Nature

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mecha...

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism  Nature

Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo ...

Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo  Nature

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex forma...

A distinct mechanism for the ABC transporter BtuCD–BtuF revealed by the dynamics of complex formation  Nature

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfe...

Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer  Nature

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor - Nature

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor  Nature

The structural basis of direct glucocorticoid-mediated transrepression - Nature

The structural basis of direct glucocorticoid-mediated transrepression  Nature

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination -...

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination  Nature

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasome...

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes  Nature

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution - Nature

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution  Nature

X-ray structure of the Yersinia pestis heme transporter HmuUV - Nature

X-ray structure of the Yersinia pestis heme transporter HmuUV  Nature

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex form...

Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation  Nature

Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S...

Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit  Nature

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macroc...

The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain  Nature

Privateer: software for the conformational validation of carbohydrate structures - Nature

Privateer: software for the conformational validation of carbohydrate structures  Nature

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant...

Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant  Nature

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription comp...

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes  Nature

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A - Nature

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A  Nature

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mou...

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells  Nature

Mechanism of potassium-channel selectivity revealed by Na - Nature

Mechanism of potassium-channel selectivity revealed by Na  Nature

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 - Nature

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2  Nature

ring of the yeast mitochondrial ATP synthase in the open conformation - Nature

ring of the yeast mitochondrial ATP synthase in the open conformation  Nature

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction -...

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction  Nature

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA - Nature

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA  Nature

Bidirectional processing of pri-miRNAs with branched terminal loops by Arabidopsis Dicer-like1 - ...

Bidirectional processing of pri-miRNAs with branched terminal loops by Arabidopsis Dicer-like1  Nature

PTEN is a protein tyrosine phosphatase for IRS1 - Nature

PTEN is a protein tyrosine phosphatase for IRS1  Nature

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human geno...

Mechanisms for U2AF to define 3′ splice sites and regulate alternative splicing in the human genome  Nature

Say it with proteins: an alphabet of crystal structures - Nature

Say it with proteins: an alphabet of crystal structures  Nature

Bimodal expression of PHO84 is modulated by early termination of antisense transcription - Nature

Bimodal expression of PHO84 is modulated by early termination of antisense transcription  Nature

Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and R...

Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1  Nature

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by th...

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne  Nature

Structural basis of respiratory syncytial virus neutralization by motavizumab - Nature

Structural basis of respiratory syncytial virus neutralization by motavizumab  Nature

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair - Nature

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair  Nature

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain - Nature

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain  Nature

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair - Nature

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair  Nature

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylat...

MacroH2A1.1 and PARP-1 cooperate to regulate transcription by promoting CBP-mediated H2B acetylation  Nature

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev - Nature

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev  Nature

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubuli...

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin  Nature

A complex network of factors with overlapping affinities represses splicing through intronic elem...

A complex network of factors with overlapping affinities represses splicing through intronic elements  Nature

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4 - Nature

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4  Nature

Molecular organization of the COG vesicle tethering complex - Nature

Molecular organization of the COG vesicle tethering complex  Nature