Is a New Super Mario Bros Collection Coming to Switch 2? - VICE

Is a New Super Mario Bros Collection Coming to Switch 2?  VICE

New Super Mario Bros. U Deluxe: All of the secret exits and world skips - Digital Trends

New Super Mario Bros. U Deluxe: All of the secret exits and world skips  Digital Trends

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B -...

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B  Nature

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Editorial - Nintendo World Re...

Why New Super Mario Bros. 2 Cannot Rest on the Original's Laurels - Editorial  Nintendo World Report

NSMB’s 30th anniversary: shining a light on the invisible - Nature

NSMB’s 30th anniversary: shining a light on the invisible  Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody - Nature

Fluorescent fusion protein knockout mediated by anti-GFP nanobody  Nature

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion trans...

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport  Nature

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem ...

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells  Nature

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transpor...

Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain  Nature

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins - Nature

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins  Nature

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein - Nature

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein  Nature

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation - Nature

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation  Nature

Crystal structure of the MOP flippase MurJ in an inward-facing conformation - Nature

Crystal structure of the MOP flippase MurJ in an inward-facing conformation  Nature

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit...

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit  Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD - Nature

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD  Nature

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing path...

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway  Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis - Nature

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis  Nature

The evolutionary journey of Argonaute proteins - Nature

The evolutionary journey of Argonaute proteins  Nature

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ - Nature

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ  Nature

Transcriptional regulation by Polycomb group proteins - Nature

Transcriptional regulation by Polycomb group proteins  Nature

Structure and assembly of the NOT module of the human CCR4–NOT complex - Nature

Structure and assembly of the NOT module of the human CCR4–NOT complex  Nature

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells - Nature

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells  Nature

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay - Nature

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay  Nature

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex - Nature

Structural characterization of a eukaryotic chaperone—the ribosome-associated complex  Nature

Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality contr...

Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality control  Nature

Structural basis for bifunctional peptide recognition at human δ-opioid receptor - Nature

Structural basis for bifunctional peptide recognition at human δ-opioid receptor  Nature

'New Super Mario Bros. U Deluxe' is the best game I've ever despised - Mashable

'New Super Mario Bros. U Deluxe' is the best game I've ever despised  Mashable

A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal fu...

A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function  Nature

7SK-BAF axis controls pervasive transcription at enhancers - Nature

7SK-BAF axis controls pervasive transcription at enhancers  Nature

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre -...

Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre  Nature

Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states - Nature

Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states  Nature

Conserved mRNA-binding proteomes in eukaryotic organisms - Nature

Conserved mRNA-binding proteomes in eukaryotic organisms  Nature

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A ...

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses  Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA - Nature

Structure of the retinoid X receptor α–liver X receptor β (RXRα–LXRβ) heterodimer on DNA  Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein - Nature

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein  Nature

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's ...

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease  Nature

The RNA-binding protein repertoire of embryonic stem cells - Nature

The RNA-binding protein repertoire of embryonic stem cells  Nature

Nucleic acid polymerases use a general acid for nucleotidyl transfer - Nature

Nucleic acid polymerases use a general acid for nucleotidyl transfer  Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase - Nature

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase  Nature

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV - Nature

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV  Nature

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation...

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation  Nature

Structural basis for lipopolysaccharide extraction by ABC transporter LptB - Nature

Structural basis for lipopolysaccharide extraction by ABC transporter LptB  Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway - Nature

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway  Nature

Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase ac...

Parkin–phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity  Nature

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation - Nature

Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation  Nature

K63 polyubiquitination is a new modulator of the oxidative stress response - Nature

K63 polyubiquitination is a new modulator of the oxidative stress response  Nature

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40 ...

Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40  Nature

Perceiving the epigenetic landscape through histone readers - Nature

Perceiving the epigenetic landscape through histone readers  Nature

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate - Nature

Crystal structure of human stearoyl–coenzyme A desaturase in complex with substrate  Nature

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates...

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates  Nature

New Super Mario Bros. U Hands-on Preview - Hands-on Preview - Nintendo World Report

New Super Mario Bros. U Hands-on Preview - Hands-on Preview  Nintendo World Report

Structural basis of enzyme encapsulation into a bacterial nanocompartment - Nature

Structural basis of enzyme encapsulation into a bacterial nanocompartment  Nature

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1 - Nature

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1  Nature

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase - Nature

Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase  Nature

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid clie...

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client  Nature

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiatio...

Structure of the 40S–ABCE1 post-splitting complex in ribosome recycling and translation initiation  Nature

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa - Nature

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa  Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly - Nature

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly  Nature

Human CTP synthase filament structure reveals the active enzyme conformation - Nature

Human CTP synthase filament structure reveals the active enzyme conformation  Nature

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutatio...

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations  Nature

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin main...

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance  Nature

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution - N...

iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution  Nature

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specific...

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity  Nature

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging - Nature

Lactase nonpersistence is directed by DNA-variation-dependent epigenetic aging  Nature

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotei...

Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein A-I  Nature

Structural determinants of integrin β-subunit specificity for latent TGF-β - Nature

Structural determinants of integrin β-subunit specificity for latent TGF-β  Nature

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation - Na...

Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation  Nature

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specifici...

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity  Nature

Structural basis of the proinflammatory signaling complex mediated by TSLP - Nature

Structural basis of the proinflammatory signaling complex mediated by TSLP  Nature

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1 - Nature

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1  Nature

Structures of the human mitochondrial ribosome in native states of assembly - Nature

Structures of the human mitochondrial ribosome in native states of assembly  Nature

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity - Nature

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity  Nature

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to tha...

Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs  Nature

The structural basis of direct glucocorticoid-mediated transrepression - Nature

The structural basis of direct glucocorticoid-mediated transrepression  Nature

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made protei...

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies  Nature

A glimpse into the C-type-inactivated state for a Potassium Channel - Nature

A glimpse into the C-type-inactivated state for a Potassium Channel  Nature

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cel...

A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells  Nature

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange ...

A U1 snRNP–specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange  Nature

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation - N...

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation  Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease - Nature

T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease  Nature

An interactive environment for agile analysis and visualization of ChIP-sequencing data - Nature

An interactive environment for agile analysis and visualization of ChIP-sequencing data  Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins - Nature

Structural insights into the mechanism of abscisic acid signaling by PYL proteins  Nature

Position effects influence HIV latency reversal - Nature

Position effects influence HIV latency reversal  Nature

#1 - New Super Mario Bros. U - Nintendo World Report

#1 - New Super Mario Bros. U  Nintendo World Report

53BP1 fosters fidelity of homology-directed DNA repair - Nature

53BP1 fosters fidelity of homology-directed DNA repair  Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin - Nature

The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin  Nature

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation - Nature

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation  Nature

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site select...

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity  Nature

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis w...

A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer  Nature

Structural basis of HIV-1 resistance to AZT by excision - Nature

Structural basis of HIV-1 resistance to AZT by excision  Nature

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization...

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization  Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1 - Nature

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1  Nature

A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding ...

A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding  Nature

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cell...

Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism  Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding - Nature

How mutations in tRNA distant from the anticodon affect the fidelity of decoding  Nature

Large-scale ATP-independent nucleosome unfolding by a histone chaperone - Nature

Large-scale ATP-independent nucleosome unfolding by a histone chaperone  Nature

Structure and VP16 binding of the Mediator Med25 activator interaction domain - Nature

Structure and VP16 binding of the Mediator Med25 activator interaction domain  Nature

Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange -...

Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange  Nature

The pol II CTD: new twists in the tail - Nature

The pol II CTD: new twists in the tail  Nature

Cotranscriptional folding of a riboswitch at nucleotide resolution - Nature

Cotranscriptional folding of a riboswitch at nucleotide resolution  Nature