SMAD ~ Mission & Vision - James Madison University

SMAD ~ Mission & Vision  James Madison University

A stepwise mode of TGFβ-SMAD signaling and DNA methylation regulates naïve-to-primed pluripotency...

A stepwise mode of TGFβ-SMAD signaling and DNA methylation regulates naïve-to-primed pluripotency and differentiation  Nature.com

SULF1 expression is increased and promotes fibrosis through the TGF-β1/SMAD pathway in idiopathic...

SULF1 expression is increased and promotes fibrosis through the TGF-β1/SMAD pathway in idiopathic pulmonary fibrosis  Journal of Translational Medicine

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis - Frontiers

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis  Frontiers

Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling ...

Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling  Nature.com

Soy Peptide Ameliorate TGF-β1-Mediated Osteoblast Differentiation through Smad and MAPK Signaling...

Soy Peptide Ameliorate TGF-β1-Mediated Osteoblast Differentiation through Smad and MAPK Signaling Pathways  ACS Publications

Video expertise, teaching makes SMAD professor a Game Changer - James Madison University

Video expertise, teaching makes SMAD professor a Game Changer  James Madison University

Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Diffe...

Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation  Frontiers

Expression of individual members of the TGF-β/SMAD signalling pathway in the progression and surv...

Expression of individual members of the TGF-β/SMAD signalling pathway in the progression and survival of patients with colorectal carcinoma | Scientific Reports  Nature.com

SMAD honors 2024 graduates and scholarship winners - James Madison University

SMAD honors 2024 graduates and scholarship winners  James Madison University

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis - Frontiers

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis  Frontiers

Michelle L. Herman: Assistant Professor - James Madison University

Michelle L. Herman: Assistant Professor  James Madison University

The immune regulation and therapeutic potential of the SMAD gene family in breast cancer - Nature...

The immune regulation and therapeutic potential of the SMAD gene family in breast cancer  Nature.com

Adiponectin Modified BMSCs Alleviate Heart Fibrosis via Inhibition TGF-beta1/Smad in Diabetic Rat...

Adiponectin Modified BMSCs Alleviate Heart Fibrosis via Inhibition TGF-beta1/Smad in Diabetic Rats  Frontiers

Oroxylin A suppressed colorectal cancer metastasis by inhibiting the activation of the TGF-β/SMAD...

Oroxylin A suppressed colorectal cancer metastasis by inhibiting the activation of the TGF-β/SMAD signal pathway  Nature.com

Damon Dillman: Lecturer - James Madison University

Damon Dillman: Lecturer  James Madison University

TGF-β, IL-1β, IL-6 levels and TGF-β/Smad pathway reactivity regulate the link between allergic di...

TGF-β, IL-1β, IL-6 levels and TGF-β/Smad pathway reactivity regulate the link between allergic diseases, cancer risk, and metabolic dysregulations  Frontiers

Olivia Booker: Lecturer - James Madison University

Olivia Booker: Lecturer  James Madison University

Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathw...

Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathway  Nature.com

Correction: CDP138 silencing inhibits TGF- β /Smad signaling to impair radioresistance and metast...

Correction: CDP138 silencing inhibits TGF- β /Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer  Nature.com

Blake Shepherd: PR Marketing Specialist for The Breeze - James Madison University

Blake Shepherd: PR Marketing Specialist for The Breeze  James Madison University

HBx-induced upregulation of MAP1S drives hepatocellular carcinoma proliferation and migration via...

HBx-induced upregulation of MAP1S drives hepatocellular carcinoma proliferation and migration via MAP1S/Smad/TGF-β1 loop  ScienceDirect.com

β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway -...

β-Ecdysterone Enhanced Bone Regeneration Through the BMP-2/SMAD/RUNX2/Osterix Signaling Pathway  Frontiers

Isoliensinine suppressed gastric cancer cell proliferation and migration by targeting TGFBR1 to r...

Isoliensinine suppressed gastric cancer cell proliferation and migration by targeting TGFBR1 to regulate TGF-β-smad signaling pathways  Frontiers

The diverse effects of transforming growth factor-β and SMAD signaling pathways during the CTL re...

The diverse effects of transforming growth factor-β and SMAD signaling pathways during the CTL response  Frontiers

Nebivolol ameliorates sepsis-evoked kidney dysfunction by targeting oxidative stress and TGF-β/Sm...

Nebivolol ameliorates sepsis-evoked kidney dysfunction by targeting oxidative stress and TGF-β/Smad/p53 pathway  Nature.com

Zangsiwei prevents particulate matter-induced lung inflammation and fibrosis by inhibiting the TG...

Zangsiwei prevents particulate matter-induced lung inflammation and fibrosis by inhibiting the TGF-β/SMAD pathway  ScienceDirect.com

Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-...

Modulating pancreatic cancer microenvironment: The efficacy of Huachansu in mouse models via TGF-β/Smad pathway  ScienceDirect.com

Eucommia ulmoides Oliver polysaccharide alleviates glucocorticoid-induced osteoporosis by stimula...

Eucommia ulmoides Oliver polysaccharide alleviates glucocorticoid-induced osteoporosis by stimulating bone formation via ERK/BMP-2/SMAD signaling  Nature.com

Mechanism of action of non-coding RNAs and traditional Chinese medicine in myocardial fibrosis: F...

Mechanism of action of non-coding RNAs and traditional Chinese medicine in myocardial fibrosis: Focus on the TGF-β/Smad signaling pathway  Frontiers

Serum iron overload activates the SMAD pathway and hepcidin expression of hepatocytes via SMURF1 ...

Serum iron overload activates the SMAD pathway and hepcidin expression of hepatocytes via SMURF1  EurekAlert

The Interplay Between TGF-β Signaling and Cell Metabolism - Frontiers

The Interplay Between TGF-β Signaling and Cell Metabolism  Frontiers

Retraction: LINC00174 facilitates cell proliferation, cell migration and tumor growth of osteosar...

Retraction: LINC00174 facilitates cell proliferation, cell migration and tumor growth of osteosarcoma via regulating the TGF-β/SMAD signaling pathway and upregulating SSH2 expression  Frontiers

Qianggan Ruanjian Pill ameliorates liver fibrosis through regulation of the TGF-β1/Smad and PI3K/...

Qianggan Ruanjian Pill ameliorates liver fibrosis through regulation of the TGF-β1/Smad and PI3K/AKT signalling pathways  ScienceDirect.com

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Act...

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2  Frontiers

Differential Smad2/3 linker phosphorylation is a crosstalk mechanism of Rho/ROCK and canonical TG...

Differential Smad2/3 linker phosphorylation is a crosstalk mechanism of Rho/ROCK and canonical TGF-β3 signaling in tenogenic differentiation  Nature.com

Umbilical cord mesenchymal stem cell-derived exosomes inhibits fibrosis in human endometrial stro...

Umbilical cord mesenchymal stem cell-derived exosomes inhibits fibrosis in human endometrial stromal cells via miR-140-3p/FOXP1/Smad axis  Nature.com

Retraction: Exosomal miR-128-3p promotes epithelial-to-mesenchymal transition in colorectal cance...

Retraction: Exosomal miR-128-3p promotes epithelial-to-mesenchymal transition in colorectal cancer cells by targeting FOXO4 via TGF-β/SMAD and JAK/STAT3 signaling  Frontiers

Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling path...

Jiawei Maxing Shigan Tang alleviates radiation-induced lung injury via TGF-β1/Smad signaling pathway mediated by regulatory T cells  ScienceDirect.com

Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and L...

Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF‐β/Smad Signaling Pathway  Wiley Online Library

SMAD ~ Study Abroad - James Madison University

SMAD ~ Study Abroad  James Madison University

'Hopefully, we can make a difference': Moms in Salamanca putting a spotlight on drug abuse - WKBW...

'Hopefully, we can make a difference': Moms in Salamanca putting a spotlight on drug abuse  WKBW 7 News Buffalo

Transcriptional cofactors Ski and SnoN are major regulators of the TGF-β/Smad signaling pathway i...

Transcriptional cofactors Ski and SnoN are major regulators of the TGF-β/Smad signaling pathway in health and disease  Nature.com

Ziziphus spina-christi L. extract attenuates bleomycin-induced lung fibrosis in mice via regulati...

Ziziphus spina-christi L. extract attenuates bleomycin-induced lung fibrosis in mice via regulating TGF-β1/SMAD pathway: LC-MS/MS Metabolic profiling, chemical composition, and histology studies  ScienceDirect.com

Internships for SMAD Students - James Madison University

Internships for SMAD Students  James Madison University

Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improvin...

Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease  Frontiers

See the winners of the 2022 SMAD awards - James Madison University

See the winners of the 2022 SMAD awards  James Madison University

Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/...

Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway  Frontiers

SMAD seniors to show off their projects - James Madison University

SMAD seniors to show off their projects  James Madison University

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treat...

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment  ScienceDirect.com

Genome-wide mechanisms of Smad binding - Oncogene - Nature.com

Genome-wide mechanisms of Smad binding - Oncogene  Nature.com

SMAD ~ Student Opportunities - James Madison University

SMAD ~ Student Opportunities  James Madison University

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors - Na...

Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors  Nature.com

Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate ...

Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation  ScienceDirect.com

SMAD ~ Planning a Visit - James Madison University

SMAD ~ Planning a Visit  James Madison University

JNK regulates muscle remodeling via myostatin/SMAD inhibition - Nature.com

JNK regulates muscle remodeling via myostatin/SMAD inhibition  Nature.com

Bletilla striata polysaccharide attenuated the progression of pulmonary fibrosis by inhibiting TG...

Bletilla striata polysaccharide attenuated the progression of pulmonary fibrosis by inhibiting TGF-β1/Smad signaling pathway  ScienceDirect.com

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replicati...

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells  ScienceDirect.com

State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual ce...

State- and stimulus-specific dynamics of SMAD signaling determine fate decisions in individual cells  pnas.org

The Smad Dependent TGF-β and BMP Signaling Pathway in Bone Remodeling and Therapies - Frontiers

The Smad Dependent TGF-β and BMP Signaling Pathway in Bone Remodeling and Therapies  Frontiers

TGF-β/SMAD canonical pathway induces the expression of transcriptional cofactor TAZ in liver canc...

TGF-β/SMAD canonical pathway induces the expression of transcriptional cofactor TAZ in liver cancer cells  ScienceDirect.com

How to Apply to SMAD - James Madison University

How to Apply to SMAD  James Madison University

The clinical utilization of SNIP1 and its pathophysiological mechanisms in disease - ScienceDirec...

The clinical utilization of SNIP1 and its pathophysiological mechanisms in disease  ScienceDirect.com

Joe Loyacano: SMAD Academic Advisor and Lecturer - James Madison University

Joe Loyacano: SMAD Academic Advisor and Lecturer  James Madison University

SMAD ~ Our Program - James Madison University

SMAD ~ Our Program  James Madison University

Concurrent YAP/TAZ and SMAD signaling mediate vocal fold fibrosis - Nature.com

Concurrent YAP/TAZ and SMAD signaling mediate vocal fold fibrosis  Nature.com

Regulation of TGF-β1-induced pro-apoptotic signaling by growth factor receptors and extracellular...

Regulation of TGF-β1-induced pro-apoptotic signaling by growth factor receptors and extracellular matrix receptor integrins in the liver  Frontiers

London Study Abroad: Student Stories - James Madison University

London Study Abroad: Student Stories  James Madison University

Non-Smad pathways in TGF-β signaling - Cell Research - Nature.com

Non-Smad pathways in TGF-β signaling - Cell Research  Nature.com

Nucleocytoplasmic shuttling of Smad proteins - Nature.com

Nucleocytoplasmic shuttling of Smad proteins  Nature.com

Smad-dependent and Smad-independent pathways in TGF-β family signalling - Nature.com

Smad-dependent and Smad-independent pathways in TGF-β family signalling  Nature.com

The role of SMAD signaling in hypertrophic obstructive cardiomyopathy: an immunohistopathological...

The role of SMAD signaling in hypertrophic obstructive cardiomyopathy: an immunohistopathological study in pediatric and adult patients  Nature.com

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling...

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling  Frontiers

SMAD students and professor help hatch new school’s logo - James Madison University

SMAD students and professor help hatch new school’s logo  James Madison University

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal act...

TGFβ/cyclin D1/Smad-mediated inhibition of BMP4 promotes breast cancer stem cell self-renewal activity  Nature.com

NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling - Science

NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling  Science

Dual SMAD inhibition and Wnt inhibition enable efficient and reproducible differentiations of ind...

Dual SMAD inhibition and Wnt inhibition enable efficient and reproducible differentiations of induced pluripotent stem cells into retinal ganglion cells  Nature.com

Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebr...

Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells  Nature.com

Bone morphogenetic protein 4 inhibits rat stem/progenitor Leydig cell development and regeneratio...

Bone morphogenetic protein 4 inhibits rat stem/progenitor Leydig cell development and regeneration via SMAD-dependent and SMAD-independent signaling  Nature.com

Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in en...

Integration of TGF-β-induced Smad signaling in the insulin-induced transcriptional response in endothelial cells  Nature.com

Joe Hinshaw: Interim Director and Professor - James Madison University

Joe Hinshaw: Interim Director and Professor  James Madison University

Targeting progranulin alleviated silica particles-induced pulmonary inflammation and fibrosis via...

Targeting progranulin alleviated silica particles-induced pulmonary inflammation and fibrosis via decreasing Il-6 and Tgf-β1/Smad  ScienceDirect.com

David Wang: Associate Professor - James Madison University

David Wang: Associate Professor  James Madison University

A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone - Nature.com

A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone  Nature.com

Elisabeth Kvernen: Assistant Professor - James Madison University

Elisabeth Kvernen: Assistant Professor  James Madison University

Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proan...

Prrx1 promotes stemness and angiogenesis via activating TGF-β/smad pathway and upregulating proangiogenic factors in glioma  Nature.com

Giving to SMAD - James Madison University

Giving to SMAD  James Madison University

Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage speci...

Oct1 cooperates with the Smad family of transcription factors to promote mesodermal lineage specification  Science

Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 a...

Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension  ACS Publications

Morgan Smalls: Assistant Professor - James Madison University

Morgan Smalls: Assistant Professor  James Madison University

Getting ‘Smad’ about obesity and diabetes - Nature.com

Getting ‘Smad’ about obesity and diabetes  Nature.com

SMAD proteins control DROSHA-mediated microRNA maturation - Nature.com

SMAD proteins control DROSHA-mediated microRNA maturation  Nature.com

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling...

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling  Nature.com

Quantitative relationships between SMAD dynamics and target gene activation kinetics in single li...

Quantitative relationships between SMAD dynamics and target gene activation kinetics in single live cells  Nature.com

SMAD alumni offer wisdom, support to students at SMAD Day '22 - James Madison University

SMAD alumni offer wisdom, support to students at SMAD Day '22  James Madison University

Association of TGF-β Canonical Signaling-Related Core Genes With Aortic Aneurysms and Aortic Diss...

Association of TGF-β Canonical Signaling-Related Core Genes With Aortic Aneurysms and Aortic Dissections  Frontiers

CDP138 silencing inhibits TGF- β /Smad signaling to impair radioresistance and metastasis via GDF...

CDP138 silencing inhibits TGF- β /Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer  Nature.com

Congratulations to SMAD scholarship winners and outstanding seniors - James Madison University

Congratulations to SMAD scholarship winners and outstanding seniors  James Madison University

Identification and characterization of an R-Smad homologue (Hco-DAF-8) from Haemonchus contortus ...

Identification and characterization of an R-Smad homologue (Hco-DAF-8) from Haemonchus contortus  Parasites & Vectors

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewa...

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal  Nature.com