"TGM2" の関連情報検索結果

Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation - Nature



Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation  Nature

Stiffness-activated Hepatic Stellate Cells boost HCC Migration via TGM2/ITGB1-mediated Matrix Rem...



Stiffness-activated Hepatic Stellate Cells boost HCC Migration via TGM2/ITGB1-mediated Matrix Remodeling and Mitochondrial Transfer  ScienceDirect.com

Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Ex...



Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis  ACS Publications

Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP ...



Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP in Senescent Microglia  Wiley Online Library

Transglutaminase 2–mediated glutamine deamidation enhances p21 stability during senescence - PNAS



Transglutaminase 2–mediated glutamine deamidation enhances p21 stability during senescence  PNAS

Expression analysis of TGM1 and TGM2 in chicken tissues and cells. RNA... - researchgate.net



Expression analysis of TGM1 and TGM2 in chicken tissues and cells. RNA...  researchgate.net

TGM2-mediated histone serotonylation promotes HCC progression via MYC signalling pathway - Scienc...



TGM2-mediated histone serotonylation promotes HCC progression via MYC signalling pathway  ScienceDirect.com

Transglutaminase 2 function in glioblastoma tumor efferocytosis - Cell Death & Disease - Nature



Transglutaminase 2 function in glioblastoma tumor efferocytosis - Cell Death & Disease  Nature

Role of transglutaminase 2 in promoting biglycan synthesis in idiopathic gingival fibromatosis - ...



Role of transglutaminase 2 in promoting biglycan synthesis in idiopathic gingival fibromatosis  BMC Oral Health

(PDF) Transglutaminase 2 exacerbates ovarian cancer survival by inactivating GSK3β - researchgate...



(PDF) Transglutaminase 2 exacerbates ovarian cancer survival by inactivating GSK3β  researchgate.net

Macrophage response to fibrin structure mediated by Tgm2-dependent mitochondrial mechanosensing -...



Macrophage response to fibrin structure mediated by Tgm2-dependent mitochondrial mechanosensing  ScienceDirect.com

Figure 8: Increased adipocyte number in Tgm2−/− mouse WAT. (a) H&E... - researchgate.net



Figure 8: Increased adipocyte number in Tgm2−/− mouse WAT. (a) H&E...  researchgate.net

Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor rec...



Transglutaminase 2 modulates inflammatory angiogenesis via vascular endothelial growth factor receptor 2 pathway in inflammatory bowel disease  ScienceDirect.com

Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer - Nature



Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer  Nature

Figure 1. Interconnected network of TGM2-NFKB and IL6-STAT3 signaling... - researchgate.net



Figure 1. Interconnected network of TGM2-NFKB and IL6-STAT3 signaling...  researchgate.net

Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis - ScienceDir...



Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis  ScienceDirect.com

Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvemen...



Tubuloside A alleviates postmyocardial infarction cardiac fibrosis by inhibiting TGM2: Involvement of inflammation and mitochondrial pathway apoptosis  ScienceDirect.com

Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of ...



Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway  ScienceDirect.com

TGM2-mediated histone transglutamination is dictated by steric accessibility - PNAS



TGM2-mediated histone transglutamination is dictated by steric accessibility  PNAS

Schematic representation of transglutaminase 2 (TG2) activation and the... - researchgate.net



Schematic representation of transglutaminase 2 (TG2) activation and the...  researchgate.net

Three-dimensional structure of human transglutaminase 2 (TG2) with... - researchgate.net



Three-dimensional structure of human transglutaminase 2 (TG2) with...  researchgate.net

Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transami...



Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2 -C277S mouse model  Nature

FIGURE 4: Influence of LDN-27219 on the inhibition of hTGase by GTP. At... - researchgate.net



FIGURE 4: Influence of LDN-27219 on the inhibition of hTGase by GTP. At...  researchgate.net

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor sup...



Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53  Nature

Unique characteristics of lung-resident neutrophils are maintained by PGE2/PKA/Tgm2-mediated sign...



Unique characteristics of lung-resident neutrophils are maintained by PGE2/PKA/Tgm2-mediated signaling  ScienceDirect.com

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression...



A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells  Frontiers

Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers - Na...



Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers  Nature

Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therape...



Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target  Nature

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling - J...



TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling  Journal of Orthopaedic Surgery and Research

Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent...



Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis  Nature

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the impo...



Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation  Frontiers

Diagnostic and Prognostic Values of Serum EpCAM, TGM2, and HE4 Levels in Endometrial Cancer - Fro...



Diagnostic and Prognostic Values of Serum EpCAM, TGM2, and HE4 Levels in Endometrial Cancer  Frontiers

TGM2 mode of action and amine donor substrates: (A) Catalytic mechanism... - researchgate.net



TGM2 mode of action and amine donor substrates: (A) Catalytic mechanism...  researchgate.net

N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapog...



N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapogenin in rheumatoid arthritis fibroblast-like synoviocytes  ScienceDirect.com

Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating...



Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating immune cells in skin cutaneous melanoma  Nature

Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular c...



Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia | Communications Biology  Nature

Piezo1 channel causes lens sclerosis via transglutaminase 2 activation - ScienceDirect.com



Piezo1 channel causes lens sclerosis via transglutaminase 2 activation  ScienceDirect.com

Transglutaminase 2—a novel inhibitor of adipogenesis - Nature



Transglutaminase 2—a novel inhibitor of adipogenesis  Nature

MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt...



MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling  Nature

Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF‐κB Signaling - Wiley Online Library



Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF‐κB Signaling  Wiley Online Library

Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell gro...



Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death  Nature

Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in h...



Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia  Nature

The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promy...



The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promyelocytic leukemia  BMC Cancer

GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic ...



GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition  ScienceDirect.com

Transglutaminase 2 regulates terminal erythroid differentiation via cross-linking activity - Fron...



Transglutaminase 2 regulates terminal erythroid differentiation via cross-linking activity  Frontiers

The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/...



The NEAT1_2/miR-491 Axis Modulates Papillary Thyroid Cancer Invasion and Metastasis Through TGM2/NFκb/FN1 Signaling  Frontiers

SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fus...



SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes  Taylor & Francis Online

Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive defic...



Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice  Wiley Online Library

P4‐028: The expression of TGM2 in the Alzheimer brain is restricted to blood vessels - Wiley



P4‐028: The expression of TGM2 in the Alzheimer brain is restricted to blood vessels  Wiley

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe - ScienceDirect.com



A spatially multiplexed voltammetric magneto-sandwich assay involving Fe  ScienceDirect.com

Zedira presents new TGM2 inhibitors - BioWorld MedTech



Zedira presents new TGM2 inhibitors  BioWorld MedTech

Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus c...



Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus cell death  Nature

188Re-labeled GX1 dimer as a novel dual-functional probe targeting TGM2 for imaging and antiangio...



188Re-labeled GX1 dimer as a novel dual-functional probe targeting TGM2 for imaging and antiangiogenic therapy of gastric cancer  ScienceDirect.com

Expression of concern: Compensatory increase of transglutaminase 2 is responsible for resistance ...



Expression of concern: Compensatory increase of transglutaminase 2 is responsible for resistance to mTOR inhibitor treatment | PLOS One  PLOS

Figure 2. Structural and functional domains and 3-D model of TGM2. A.... - researchgate.net



Figure 2. Structural and functional domains and 3-D model of TGM2. A....  researchgate.net

Transglutaminase 2 is upregulated in primary hepatocellular carcinoma with early recurrence as de...



Transglutaminase 2 is upregulated in primary hepatocellular carcinoma with early recurrence as determined by proteomic profiles  Spandidos Publications

Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumo...



Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer  Nature

Figure 3. Schematic diagram of TGM2 and different isoforms and the... - researchgate.net



Figure 3. Schematic diagram of TGM2 and different isoforms and the...  researchgate.net

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin ...



Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow  Nature

TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis an...



TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer’s disease  ScienceDirect.com

Figure 4: Tgm2−/− MEFs show decreased β-catenin nuclear translocation.... - researchgate.net



Figure 4: Tgm2−/− MEFs show decreased β-catenin nuclear translocation....  researchgate.net

Conserved catalytic triad among the transglutaminase 2 family. The... - researchgate.net



Conserved catalytic triad among the transglutaminase 2 family. The...  researchgate.net

Structural comparison of transglutaminase 2 (TG2) family members. a... - researchgate.net



Structural comparison of transglutaminase 2 (TG2) family members. a...  researchgate.net

Neuropathology and Applied Neurobiology | BNS Journal - Wiley Online Library



Neuropathology and Applied Neurobiology | BNS Journal  Wiley Online Library

Figure 2: TG2-mediated cell signaling. Chronic inflammation and... - researchgate.net



Figure 2: TG2-mediated cell signaling. Chronic inflammation and...  researchgate.net

Inhibitors for human TGM2 enzyme - Nature



Inhibitors for human TGM2 enzyme  Nature

Schematic showing how TG2 inhibitors block fibrosis during IPF. The... - researchgate.net



Schematic showing how TG2 inhibitors block fibrosis during IPF. The...  researchgate.net

Protein serotonylation by 5-propargylserotonin: (A) The approach... - researchgate.net



Protein serotonylation by 5-propargylserotonin: (A) The approach...  researchgate.net

Defective proteostasis in celiac disease as a new therapeutic target - Nature



Defective proteostasis in celiac disease as a new therapeutic target  Nature

Functional diversity of transglutaminase 2 (TG2). a TG2 is... - researchgate.net



Functional diversity of transglutaminase 2 (TG2). a TG2 is...  researchgate.net

Figure 3: Cellular distribution and functions of TG2. Although... - researchgate.net



Figure 3: Cellular distribution and functions of TG2. Although...  researchgate.net

Figure 3. Roles of TG2 in the wound healing response. The scheme... - researchgate.net



Figure 3. Roles of TG2 in the wound healing response. The scheme...  researchgate.net

Fig. 1-Overview of system manifestations in celiac disease. The common... - researchgate.net



Fig. 1-Overview of system manifestations in celiac disease. The common...  researchgate.net

Fig. 1. Structure and two differential state of TG2 activity. (a, b)... - researchgate.net



Fig. 1. Structure and two differential state of TG2 activity. (a, b)...  researchgate.net

Figure 7. (A) WT and TG2-/-MeFs under starvation conditions. WT MeFs... - researchgate.net



Figure 7. (A) WT and TG2-/-MeFs under starvation conditions. WT MeFs...  researchgate.net

Table 1 Effects of IgG and lgA purified from the serum of patients with... - researchgate.net



Table 1 Effects of IgG and lgA purified from the serum of patients with...  researchgate.net

Figure 7. Proposed model for the mechanisms by which TG2 activates... - researchgate.net



Figure 7. Proposed model for the mechanisms by which TG2 activates...  researchgate.net

Tetris The Absolute Grand Master 2 Plus drops into the Arcade Archives - Destructoid



Tetris The Absolute Grand Master 2 Plus drops into the Arcade Archives  Destructoid