"TGM2" の関連情報検索結果

Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation - Nature



Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation  Nature

Stiffness-activated Hepatic Stellate Cells boost HCC Migration via TGM2/ITGB1-mediated Matrix Rem...



Stiffness-activated Hepatic Stellate Cells boost HCC Migration via TGM2/ITGB1-mediated Matrix Remodeling and Mitochondrial Transfer  ScienceDirect.com

Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Ex...



Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis  ACS Publications

Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP ...



Tgm2-Catalyzed Covalent Cross-Linking of IκBα Drives NF-κB Nuclear Translocation to Promote SASP in Senescent Microglia  Wiley Online Library

Fig. 6 TGM2 promotes P53 degradation after irradiation in GBM cells.... - researchgate.net



Fig. 6 TGM2 promotes P53 degradation after irradiation in GBM cells....  researchgate.net

TGM2-mediated histone transglutamination is dictated by steric accessibility - PNAS



TGM2-mediated histone transglutamination is dictated by steric accessibility  PNAS

Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of ...



Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway  ScienceDirect.com

Figure 8: Increased adipocyte number in Tgm2−/− mouse WAT. (a) H&E... - researchgate.net



Figure 8: Increased adipocyte number in Tgm2−/− mouse WAT. (a) H&E...  researchgate.net

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling - J...



TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling  Journal of Orthopaedic Surgery and Research

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression...



A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells  Frontiers

Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer - Nature



Expression of transglutaminase-2 (TGM2) in the prognosis of female invasive breast cancer  Nature

Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis - ScienceDir...



Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis  ScienceDirect.com

Figure 1. Interconnected network of TGM2-NFKB and IL6-STAT3 signaling... - researchgate.net



Figure 1. Interconnected network of TGM2-NFKB and IL6-STAT3 signaling...  researchgate.net

Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transami...



Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2 -C277S mouse model  Nature

TG2 multifunctional roles. TG2 contributes to the posttranslational... - researchgate.net



TG2 multifunctional roles. TG2 contributes to the posttranslational...  researchgate.net

Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor sup...



Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53  Nature

Three-dimensional structure of human transglutaminase 2 (TG2) with... - researchgate.net



Three-dimensional structure of human transglutaminase 2 (TG2) with...  researchgate.net

Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus c...



Distinct conformational states enable transglutaminase 2 to promote cancer cell survival versus cell death  Nature

Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therape...



Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target  Nature

Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers - Na...



Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers  Nature

Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent...



Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis  Nature

Diagnostic and Prognostic Values of Serum EpCAM, TGM2, and HE4 Levels in Endometrial Cancer - Fro...



Diagnostic and Prognostic Values of Serum EpCAM, TGM2, and HE4 Levels in Endometrial Cancer  Frontiers

Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the impo...



Aberrant expression of transglutaminase 2 in pancreas and thymus of NOD mice underscores the importance of deamidation in neoantigen generation  Frontiers

Piezo1 channel causes lens sclerosis via transglutaminase 2 activation - ScienceDirect.com



Piezo1 channel causes lens sclerosis via transglutaminase 2 activation  ScienceDirect.com

Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular c...



Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia | Communications Biology  Nature

Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating...



Promising prognostic value of Transglutaminase type 2 and its correlation with tumor-infiltrating immune cells in skin cutaneous melanoma  Nature

Figure 1. Overexpression and detection human TGM2-002 protein in... - researchgate.net



Figure 1. Overexpression and detection human TGM2-002 protein in...  researchgate.net

TGM2 mode of action and amine donor substrates: (A) Catalytic mechanism... - researchgate.net



TGM2 mode of action and amine donor substrates: (A) Catalytic mechanism...  researchgate.net

Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell gro...



Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death  Nature

Transglutaminase 2—a novel inhibitor of adipogenesis - Nature



Transglutaminase 2—a novel inhibitor of adipogenesis  Nature

MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt...



MiR-532-3p suppresses colorectal cancer progression by disrupting the ETS1/TGM2 axis-mediated Wnt/β-catenin signaling  Nature

N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapog...



N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapogenin in rheumatoid arthritis fibroblast-like synoviocytes  ScienceDirect.com

Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in h...



Tissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia  Nature

Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF‐κB Signaling - Wiley Online Library



Propofol Suppresses Microglia Inflammation by Targeting TGM2/NF‐κB Signaling  Wiley Online Library

Fig. 6 Association between TGM2 expression and macrophage infiltration... - researchgate.net



Fig. 6 Association between TGM2 expression and macrophage infiltration...  researchgate.net

The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promy...



The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promyelocytic leukemia  BMC Cancer

Transglutaminase 2 regulates terminal erythroid differentiation via cross-linking activity - Fron...



Transglutaminase 2 regulates terminal erythroid differentiation via cross-linking activity  Frontiers

Chronic liver injury drives non‐traditional intrahepatic fibrin(ogen) crosslinking via tissue tra...



Chronic liver injury drives non‐traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase  ScienceDirect.com

Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive defic...



Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice  Wiley Online Library

TGM2 as AP-2α target gene and regulator of cell cycle. A, ChIP-seq... - researchgate.net



TGM2 as AP-2α target gene and regulator of cell cycle. A, ChIP-seq...  researchgate.net

Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis...



Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis  Nature

Figure 3. Schematic diagram of TGM2 and different isoforms and the... - researchgate.net



Figure 3. Schematic diagram of TGM2 and different isoforms and the...  researchgate.net

A spatially multiplexed voltammetric magneto-sandwich assay involving Fe - ScienceDirect.com



A spatially multiplexed voltammetric magneto-sandwich assay involving Fe  ScienceDirect.com

Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency ...



Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines  Nature

Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin ...



Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow  Nature

Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumo...



Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer  Nature

Conserved catalytic triad among the transglutaminase 2 family. The... - researchgate.net



Conserved catalytic triad among the transglutaminase 2 family. The...  researchgate.net

TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis an...



TG2 promotes amyloid beta aggregates: Impact on ER-mitochondria crosstalk, calcium homeostasis and synaptic function in Alzheimer’s disease  ScienceDirect.com

Inhibitors for human TGM2 enzyme - Nature



Inhibitors for human TGM2 enzyme  Nature

FIG. 3. The effect of TGM2 on trophoblast turnover. A) TGM2... - researchgate.net



FIG. 3. The effect of TGM2 on trophoblast turnover. A) TGM2...  researchgate.net

Structural comparison of transglutaminase 2 (TG2) family members. a... - researchgate.net



Structural comparison of transglutaminase 2 (TG2) family members. a...  researchgate.net

Schematic representation of transglutaminase 2 (TG2) activation and the... - researchgate.net



Schematic representation of transglutaminase 2 (TG2) activation and the...  researchgate.net

Neuropathology and Applied Neurobiology | BNS Journal - Wiley Online Library



Neuropathology and Applied Neurobiology | BNS Journal  Wiley Online Library

Figure 4. The Active Site of TG2 and Enzyme–Inhibitor Interactions (A)... - researchgate.net



Figure 4. The Active Site of TG2 and Enzyme–Inhibitor Interactions (A)...  researchgate.net

Figure 2: TG2-mediated cell signaling. Chronic inflammation and... - researchgate.net



Figure 2: TG2-mediated cell signaling. Chronic inflammation and...  researchgate.net

Defective proteostasis in celiac disease as a new therapeutic target - Nature



Defective proteostasis in celiac disease as a new therapeutic target  Nature

FSK promotes the osteoblastic differentiation of MC3T3‐E1 cells and... - researchgate.net



FSK promotes the osteoblastic differentiation of MC3T3‐E1 cells and...  researchgate.net

Protein serotonylation by 5-propargylserotonin: (A) The approach... - researchgate.net



Protein serotonylation by 5-propargylserotonin: (A) The approach...  researchgate.net

Transglutaminase 2: A multi-tasking protein in the complex circuitry of inflammation and cancer -...



Transglutaminase 2: A multi-tasking protein in the complex circuitry of inflammation and cancer  ScienceDirect.com

Functional diversity of transglutaminase 2 (TG2). a TG2 is... - researchgate.net



Functional diversity of transglutaminase 2 (TG2). a TG2 is...  researchgate.net

FIG. 1. Forskolin-induced CREB phosphorylation at Ser 133 is enhanced... - researchgate.net



FIG. 1. Forskolin-induced CREB phosphorylation at Ser 133 is enhanced...  researchgate.net

Schematic representation of the four domains of TG2 (N-terminal... - researchgate.net



Schematic representation of the four domains of TG2 (N-terminal...  researchgate.net

Figure 3: Cellular distribution and functions of TG2. Although... - researchgate.net



Figure 3: Cellular distribution and functions of TG2. Although...  researchgate.net

Figure 3. Roles of TG2 in the wound healing response. The scheme... - researchgate.net



Figure 3. Roles of TG2 in the wound healing response. The scheme...  researchgate.net

Fig. 1-Overview of system manifestations in celiac disease. The common... - researchgate.net



Fig. 1-Overview of system manifestations in celiac disease. The common...  researchgate.net

Figure 2. Progressive increase in TG2 expression during the course of... - researchgate.net



Figure 2. Progressive increase in TG2 expression during the course of...  researchgate.net

Table 1 Effects of IgG and lgA purified from the serum of patients with... - researchgate.net



Table 1 Effects of IgG and lgA purified from the serum of patients with...  researchgate.net

Figure 7. (A) WT and TG2-/-MeFs under starvation conditions. WT MeFs... - researchgate.net



Figure 7. (A) WT and TG2-/-MeFs under starvation conditions. WT MeFs...  researchgate.net

Figure 3. A proposed role of tissue transglutaminase (TG2) in the... - researchgate.net



Figure 3. A proposed role of tissue transglutaminase (TG2) in the...  researchgate.net

Fig. 1. Genotypes detected by PCR. A : breeding scheme for mice. B :... - researchgate.net



Fig. 1. Genotypes detected by PCR. A : breeding scheme for mice. B :...  researchgate.net

FIGURE 6. Binding of monoclonal antibodies to mutants of TG2 as... - researchgate.net



FIGURE 6. Binding of monoclonal antibodies to mutants of TG2 as...  researchgate.net

Primers for RT-PCR used to detect osteoblast markers and TG2 in SAOS-2. - researchgate.net



Primers for RT-PCR used to detect osteoblast markers and TG2 in SAOS-2.  researchgate.net

Figure 2: Alcohol and FFAs cause hepatic apoptosis via nuclear... - researchgate.net



Figure 2: Alcohol and FFAs cause hepatic apoptosis via nuclear...  researchgate.net

Tetris The Absolute Grand Master 2 Plus drops into the Arcade Archives - Destructoid



Tetris The Absolute Grand Master 2 Plus drops into the Arcade Archives  Destructoid