"YAP遺伝子" の関連情報検索結果

The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through s...



The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway  Nature.com

Hippo pathway in non-small cell lung cancer: mechanisms, potential targets, and biomarkers | Canc...



Hippo pathway in non-small cell lung cancer: mechanisms, potential targets, and biomarkers | Cancer Gene Therapy  Nature.com

The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes - ScienceDirect...



The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes  ScienceDirect.com

PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation - Nature.com



PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation  Nature.com

Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis...



Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis Bullosa  ScienceDirect.com

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression - Na...



Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression  Nature.com

Hippo–YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin e...



Hippo–YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass  Nature.com

Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferat...



Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation  Nature.com

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for ...



YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity  Nature.com

Concerted localization-resets precede YAP-dependent transcription - Nature.com



Concerted localization-resets precede YAP-dependent transcription  Nature.com

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac matura...



Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation  Nature.com

A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth - Na...



A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth  Nature.com

A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases - N...



A calpain-6/YAP axis in sarcoma stem cells that drives the outgrowth of tumors and metastases  Nature.com

CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression - Natu...



CYLD regulates cell ferroptosis through Hippo/YAP signaling in prostate cancer progression  Nature.com

DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP - Nature.com



DNMT3a-dermatopontin axis suppresses breast cancer malignancy via inactivating YAP  Nature.com

CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis - Na...



CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis  Nature.com

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 | Communicatio...



EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 | Communications Biology  Nature.com

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentia...



YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation  Nature.com

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therape...



Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER  Nature.com

The potential role of YAP in head and neck squamous cell carcinoma - Nature.com



The potential role of YAP in head and neck squamous cell carcinoma  Nature.com

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) c...



Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity | Cell Death & Disease  Nature.com

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs - Fred Hutchi...



New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs  Fred Hutchinson Cancer Center

Correction: TRIM58 downregulation maintains stemness via MYH9-GRK3-YAP axis activation in triple-...



Correction: TRIM58 downregulation maintains stemness via MYH9-GRK3-YAP axis activation in triple-negative breast cancer stem cells  Nature.com

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory ...



EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma  Nature.com

Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestina...



Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation  Science

Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastas...



Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma  Nature.com

YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis - ScienceDirect.com



YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis  ScienceDirect.com

Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis -...



Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis  Nature.com

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets ...



YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets  Fred Hutchinson Cancer Center

Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity...



Regulation of follicular activation signaling pathways by in vitro inhibition of YAP/TAZ activity in mouse ovaries  Nature.com

Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration | Circulation Re...



Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration | Circulation Research  AHA Journals

YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of ...



YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma  Nature.com

Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD - Nature.com



Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD  Nature.com

Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-...



Clock-modified mesenchymal stromal cells therapy rescues molecular circadian oscillation and age-related bone loss via miR142-3p/Bmal1/YAP signaling axis  Nature.com

ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer c...



ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway  Nature.com

Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation - Nature.com



Plau and Tgfbr3 are YAP-regulated genes that promote keratinocyte proliferation  Nature.com

Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy - Nature.com



Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy  Nature.com

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis ...



Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population  Nature.com

Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development -...



Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development  Nature.com

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells - Nature.com



TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells  Nature.com

ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma ...



ACADL plays a tumor-suppressor role by targeting Hippo/YAP signaling in hepatocellular carcinoma  Nature.com

H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP - JCI



H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP  JCI

The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in ...



The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice  Nature.com

YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation...



YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity  Nature.com

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Br...



KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer  ScienceDirect.com

Nexilin/ NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family...



Nexilin/ NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP  Nature.com

YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model ...



YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations  Wiley Online Library

YAP protein identified as new target for Alzheimer’s disease - Drug Target Review



YAP protein identified as new target for Alzheimer’s disease  Drug Target Review

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness - Nature.com



A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness  Nature.com

MST1/Hippo promoter gene methylation predicts poor survival in patients with malignant pleural me...



MST1/Hippo promoter gene methylation predicts poor survival in patients with malignant pleural mesothelioma in the IFCT-GFPC-0701 MAPS Phase 3 trial  Nature.com

Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells - Nature.com



Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells  Nature.com

Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enh...



Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enhancing anchorage-independent T47D cell proliferation  Nature.com

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis - Nature.com



The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis  Nature.com

Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-...



Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription  Nature.com

Differential gene expression induced by Verteporfin in endometrial cancer cells - Nature.com



Differential gene expression induced by Verteporfin in endometrial cancer cells  Nature.com

Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes ...



Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location  Nature.com

YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, su...



YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets  Nature.com