First Clinical Investigation of a Gene Therapy (YAP101) to Induce Cardiac Regeneration to Treat H...

First Clinical Investigation of a Gene Therapy (YAP101) to Induce Cardiac Regeneration to Treat Heart Failure Passes Initial Safety Hurdle  Business Wire

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs - Fred Hutchi...

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs  Fred Hutchinson Cancer Center

Targeting a gene that controls tissue growth, scientists reveal regenerative path for treating di...

Targeting a gene that controls tissue growth, scientists reveal regenerative path for treating diabetic foot ulcers  Scripps Research

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression - Na...

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression  Nature

Microscopy reveals how Hippo pathway proteins control gene activity in cancer - Medical Xpress

Microscopy reveals how Hippo pathway proteins control gene activity in cancer  Medical Xpress

Gene Therapy for Heart Attacks in Mice Just Got More Precise - Duke Today

Gene Therapy for Heart Attacks in Mice Just Got More Precise  Duke Today

The Hippo-YAP signaling pathway promotes hepatocellular carcinoma progression by inducing FHL3 ex...

The Hippo-YAP signaling pathway promotes hepatocellular carcinoma progression by inducing FHL3 expression  Nature

YAP Activity is Not Associated with Survival of Uveal Melanoma Patients and Cell Lines - Nature

YAP Activity is Not Associated with Survival of Uveal Melanoma Patients and Cell Lines  Nature

YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vi...

YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vitro  Nature

The mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy - Nature

The mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy  Nature

A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathw...

A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathways as a differentiation therapeutic target in breast cancer | Cell Death & Disease  Nature

The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through s...

The circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway  Nature

Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development -...

Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development  Nature

YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of ...

YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma  Nature

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac matura...

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation  Nature

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury - Nature

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury  Nature

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for ...

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity  Nature

Hippo pathway in non-small cell lung cancer: mechanisms, potential targets, and biomarkers | Canc...

Hippo pathway in non-small cell lung cancer: mechanisms, potential targets, and biomarkers | Cancer Gene Therapy  Nature

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory ...

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma  Nature

LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non...

LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer  Nature

ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer c...

ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway  Nature

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis ...

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population  Nature

The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulate...

The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulated by β-catenin in colorectal cancer  Nature

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) c...

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity  Nature

Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration | Circulation Re...

Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration | Circulation Research  American Heart Association Journals

Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy - Nature

Yap haploinsufficiency leads to Müller cell dysfunction and late-onset cone dystrophy  Nature

Expression of foetal gene Pontin is essential in protecting heart against pathological remodellin...

Expression of foetal gene Pontin is essential in protecting heart against pathological remodelling and cardiomyopathy  Nature

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets ...

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets  Fred Hutchinson Cancer Center

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness - Nature

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness  Nature

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis - Nature

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis  Nature

Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enh...

Nectin-4 and p95-ErbB2 cooperatively regulate Hippo signaling-dependent SOX2 gene expression, enhancing anchorage-independent T47D cell proliferation  Nature

MST1/Hippo promoter gene methylation predicts poor survival in patients with malignant pleural me...

MST1/Hippo promoter gene methylation predicts poor survival in patients with malignant pleural mesothelioma in the IFCT-GFPC-0701 MAPS Phase 3 trial  Nature

Gravity-resisting gene stops our bodies being squashed flat - Phys.org

Gravity-resisting gene stops our bodies being squashed flat  Phys.org