protects the mouse heart from myocardial infarction - Nature

protects the mouse heart from myocardial infarction  Nature

First Clinical Investigation of a Gene Therapy (YAP101) to Induce Cardiac Regeneration to Treat H...

First Clinical Investigation of a Gene Therapy (YAP101) to Induce Cardiac Regeneration to Treat Heart Failure Passes Initial Safety Hurdle  Business Wire

The Hippo-YAP signaling pathway promotes hepatocellular carcinoma progression by inducing FHL3 ex...

The Hippo-YAP signaling pathway promotes hepatocellular carcinoma progression by inducing FHL3 expression  Nature

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs - Fred Hutchi...

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs  Fred Hutchinson Cancer Center

A synthetic hyperglycemia-sensing gene circuit enhances blood glucose homeostasis in diabetic mic...

A synthetic hyperglycemia-sensing gene circuit enhances blood glucose homeostasis in diabetic mice  ScienceDirect.com

AR and YAP crosstalk: impacts on therapeutic strategies in prostate cancer - Frontiers

AR and YAP crosstalk: impacts on therapeutic strategies in prostate cancer  Frontiers

Targeting a gene that controls tissue growth, scientists reveal regenerative path for treating di...

Targeting a gene that controls tissue growth, scientists reveal regenerative path for treating diabetic foot ulcers  Scripps Research

YAP controls cell migration and invasion through a Rho GTPase switch - Science | AAAS

YAP controls cell migration and invasion through a Rho GTPase switch  Science | AAAS

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ s...

Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation  Nature

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression - Na...

Phase separation of YAP reorganizes genome topology for long-term YAP target gene expression  Nature

The mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy - Nature

The mechanism of YAP/TAZ transactivation and dual targeting for cancer therapy  Nature

YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vi...

YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vitro  Nature

Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical...

Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models  Nature

The RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquit...

The RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquitylation  Nature

ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP - Nature

ALDOA contributes to colorectal tumorigenesis and metastasis by targeting YAP  Nature

A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathw...

A novel clinically relevant antagonistic interplay between prolactin and oncogenic YAP-CCN2 pathways as a differentiation therapeutic target in breast cancer | Cell Death & Disease  Nature

Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferat...

Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation  Nature

Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation ...

Deciphering the involvement of the Hippo pathway co-regulators, YAP/TAZ in invadopodia formation and matrix degradation  Nature

Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development -...

Fat3 regulates neural progenitor cells by promoting Yap activity during spinal cord development  Nature

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury - Nature

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury  Nature

breast cancer growth by disrupting a TEAD-ERα signaling axis - Nature

breast cancer growth by disrupting a TEAD-ERα signaling axis  Nature

YAP Activity is Not Associated with Survival of Uveal Melanoma Patients and Cell Lines - Nature

YAP Activity is Not Associated with Survival of Uveal Melanoma Patients and Cell Lines  Nature

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs - Nature

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs  Nature

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets ...

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets  Fred Hutchinson Cancer Center

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) c...

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity  Nature

YAP/TAZ phase separation for transcription - Nature

YAP/TAZ phase separation for transcription  Nature

LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non...

LncRNA SFTA1P mediates positive feedback regulation of the Hippo-YAP/TAZ signaling pathway in non-small cell lung cancer  Nature

ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer c...

ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway  Nature

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therape...

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER  Nature

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 | Communicatio...

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 | Communications Biology  Nature

FRMD6 determines the cell fate towards senescence: involvement of the Hippo-YAP-CCN3 axis - Nature

FRMD6 determines the cell fate towards senescence: involvement of the Hippo-YAP-CCN3 axis  Nature

YAP-mediated mechanotransduction tunes the macrophage inflammatory response - Science | AAAS

YAP-mediated mechanotransduction tunes the macrophage inflammatory response  Science | AAAS

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory ...

EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma  Nature

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis - Nature

The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis  Nature

Hippo-Yap/Taz signalling in zebrafish regeneration - Nature

Hippo-Yap/Taz signalling in zebrafish regeneration  Nature

Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial ...

Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction  Science | AAAS

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells - Nature

TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells  Nature

YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity - Nature

YAP-dependent Wnt5a induction in hypertrophic adipocytes restrains adiposity  Nature

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis ...

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population  Nature

Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associate...

Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts  Nature

KKH sees surge in children with genetic disease that may lead to early heart attack and stroke - ...

KKH sees surge in children with genetic disease that may lead to early heart attack and stroke  The Straits Times

Making Memories - Harvard Medical School

Making Memories  Harvard Medical School

PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver f...

PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis  Nature

Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD - Nature

Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD  Nature

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis - Nature

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis  Nature

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness - Nature

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness  Nature

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression dur...

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development  Nature

Gene fusions in poroma, porocarcinoma and related adnexal skin tumours: An update - Wiley Online ...

Gene fusions in poroma, porocarcinoma and related adnexal skin tumours: An update  Wiley Online Library

GPCR ligands and TGFβ1 cooperate to induce a profibrotic phenotype and YAP/TAZ target gene expres...

GPCR ligands and TGFβ1 cooperate to induce a profibrotic phenotype and YAP/TAZ target gene expression in NHDF.  PLOS

A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of ...

A YAP/TAZ-miR-130/301 molecular circuit exerts systems-level control of fibrosis in a network of human diseases and physiologic conditions  Nature

Role of YAP/TAZ in mechanotransduction - Nature

Role of YAP/TAZ in mechanotransduction  Nature

YAP1–TFE3 gene fusion variant in clear cell stromal tumour of lung: report of two cases in suppor...

YAP1–TFE3 gene fusion variant in clear cell stromal tumour of lung: report of two cases in support of a distinct entity  Wiley Online Library

Establishment of a Pancreatic Cancer Animal Model Using the Pancreas-Targeted Hydrodynamic Gene D...

Establishment of a Pancreatic Cancer Animal Model Using the Pancreas-Targeted Hydrodynamic Gene Delivery Method | 投稿 | NIIGATA UNIVERSITY  niigata-u.ac.jp