"il-2" の関連情報検索結果

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals - ...



A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals  Science | AAAS

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alter...



Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alternatives  Fierce Biotech

National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik - Vintage Aviatio...



National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik  Vintage Aviation News

Breakthrough: New GLP-1/IL-2 Combo Drug Outperforms Standard Therapy by 42% in Alzheimer's Resear...



Breakthrough: New GLP-1/IL-2 Combo Drug Outperforms Standard Therapy by 42% in Alzheimer's Research  Stock Titan

An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to...



An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy  ScienceDirect.com

dendritic cell-derived IL-2 dictates CD4 - Nature



dendritic cell-derived IL-2 dictates CD4  Nature

Claude on Google Cloud’s Vertex AI: FedRAMP High and IL2 Authorized - Anthropic



Claude on Google Cloud’s Vertex AI: FedRAMP High and IL2 Authorized  Anthropic

The Interleukin-2 Market is Set to Reach USD 4 Billion by 2034, Driven by IL-2 Targeting Fusion P...



The Interleukin-2 Market is Set to Reach USD 4 Billion by 2034, Driven by IL-2 Targeting Fusion Proteins, Monoclonal antibodies, and Gene Therapies Across Immunology, Dermatology, Neurodegenerative Disorders, and Oncology | DelveInsight  PR Newswire

Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in pat...



Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in patients with ACS: The results of the IVORY trial and IVORY FINALE study  American Heart Association Journals

BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Can...



BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Cancer  UroToday

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People wi...



Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People with Systemic Lupus Erythematosus  Lupus Foundation of America

IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers



IL-2 based cancer immunotherapies: an evolving paradigm  Frontiers

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentia...



Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy  Science | AAAS

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...



Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective and emerging trends  Nature

Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emi...



Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography  ScienceDirect.com

A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells agains...



A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma  Science | AAAS

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T - Nature



Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T  Nature

Targeting systemic IL-2 to BCMA CAR-T cells - Nature



Targeting systemic IL-2 to BCMA CAR-T cells  Nature

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...



T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics  Nature

Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 ove...



Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer  Nature

IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines - PNAS



IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines  PNAS

The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment...



The regulatory T cell-selective interleukin-2 receptor agonist rezpegaldesleukin in the treatment of inflammatory skin diseases: two randomized, double-blind, placebo-controlled phase 1b trials  Nature

Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing...



Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing immunotherapy  ScienceDirect.com

Low-dose IL-2 promising in bullous pemphigoid treatment - Healio



Low-dose IL-2 promising in bullous pemphigoid treatment  Healio

WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game - DualShockers



WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game  DualShockers

Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection - Nature



Role of soluble interleukin-2 receptor (sIL-2R) as a predictor for severe dengue infection  Nature

IL-2–inducible T cell kinase deficiency sustains chimeric antigen receptor T cell therapy against...



IL-2–inducible T cell kinase deficiency sustains chimeric antigen receptor T cell therapy against tumor cells  JCI.org

Coya touts partnership potential as IL-2 prospect comes through small Alzheimer's study - Fierce ...



Coya touts partnership potential as IL-2 prospect comes through small Alzheimer's study  Fierce Biotech

Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-M...



Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation  Nature

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T ...



Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation  Nature

AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enh...



AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enhanced anti-tumor immunity and diminished toxicity  Frontiers

Based on the immune system: the role of the IL-2 family in pancreatic disease - Frontiers



Based on the immune system: the role of the IL-2 family in pancreatic disease  Frontiers

Oncotelic Therapeutics Announces Successful Completion of Phase 1 Trial of OT-101 and IL-2, Highl...



Oncotelic Therapeutics Announces Successful Completion of Phase 1 Trial of OT-101 and IL-2, Highlights Findings at SWCR 2025 Conference  GlobeNewswire

IL-2 Sturmovik Flying Circus Vol. IV Released - FSElite



IL-2 Sturmovik Flying Circus Vol. IV Released  FSElite

IL-2 Signaling Axis Defects: How Many Faces? - Frontiers



IL-2 Signaling Axis Defects: How Many Faces?  Frontiers

IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL - MedPage Today



IL-2 Receptor-Targeted Therapy Approved for Relapsed/Refractory CTCL  MedPage Today

The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity ...



The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity  Wiley Online Library

Synthekine Announces Presentation of New Translational Data from Phase 1a/1b Clinical Trial of α/...



Synthekine Announces Presentation of New Translational Data from Phase 1a/1b Clinical Trial of α/β Biased IL-2, STK-012, at the Society for Immunotherapy of Cancer (SITC) 39th Annual Meeting  Business Wire

A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus:...



A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus: Mechanisms, Efficacy, and Clinical Applications  Cureus

Engineered IL-2 molecule shows promise in treating autoimmune disease - McGill University



Engineered IL-2 molecule shows promise in treating autoimmune disease  McGill University

Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs - MyStateline



Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs  MyStateline

Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic AU-007 in Melanoma ...



Aulos Bioscience to Present Promising Phase 2 Data for Novel IL-2 Therapeutic AU-007 in Melanoma at AACR Annual Meeting  BioSpace

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation - Science...



Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation  ScienceDirect.com

(PDF) Low-dose IL-2 in the treatment of immune-related diseases - ResearchGate



(PDF) Low-dose IL-2 in the treatment of immune-related diseases  ResearchGate

IL-2 Korea Announcement - FSElite



IL-2 Korea Announcement  FSElite

IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy i...



IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer  BMC Medicine

De novo design of mini-binder proteins against IL-2 receptor β chain - ScienceDirect.com



De novo design of mini-binder proteins against IL-2 receptor β chain  ScienceDirect.com

The Structure of Interleukin-2 Complexed with Its Alpha Receptor - Science | AAAS



The Structure of Interleukin-2 Complexed with Its Alpha Receptor  Science | AAAS

Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 sti...



Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood  Frontiers

(PDF) Alteration in the IL-2 signal peptide affects secretion of proteinsin vitro andin vivo - Re...



(PDF) Alteration in the IL-2 signal peptide affects secretion of proteinsin vitro andin vivo  ResearchGate

Innovent braves bruising cytokine space, linking fusion protein to tumor responses in small study...



Innovent braves bruising cytokine space, linking fusion protein to tumor responses in small study  Fierce Biotech

Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model - Frontiers



Low Dose Interleukin-2 Ameliorates Sjögren’s Syndrome in a Murine Model  Frontiers

FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow... - ResearchGate



FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow...  ResearchGate

Figure 3. IL-2 modification for cellular targeting and prolonged... - ResearchGate



Figure 3. IL-2 modification for cellular targeting and prolonged...  ResearchGate

IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. t...



IFNγ-secreting T cells that highly express IL-2 potently inhibit the growth of intracellular M. tuberculosis in macrophages  Frontiers

IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation - Al‐Aghba...



IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation - Al‐Aghbar - 2024 - Immunology  Wiley Online Library

Fig. 4. IL-2-induced T cell proliferation in the presence of high-dose... - ResearchGate



Fig. 4. IL-2-induced T cell proliferation in the presence of high-dose...  ResearchGate

FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow... - ResearchGate



FIGURE 3. IL-2 controls the frequency of T reg cells in vivo. A, Flow...  ResearchGate

Fig. 1. Interleukin-2 takes center stage. The different functional... - ResearchGate



Fig. 1. Interleukin-2 takes center stage. The different functional...  ResearchGate

Korea IL-2 Series Brings The Military Flight Sim To PC VR Next Year - UploadVR



Korea IL-2 Series Brings The Military Flight Sim To PC VR Next Year  UploadVR

Patient Overcomes Advanced Melanoma With Rare IL-2 Treatment - University of Cincinnati



Patient Overcomes Advanced Melanoma With Rare IL-2 Treatment  University of Cincinnati

Fig. 3. Validation of IL-2 activation in gluten-induced recall... - ResearchGate



Fig. 3. Validation of IL-2 activation in gluten-induced recall...  ResearchGate

GRIT and Quangang announce IL-2 T-cell therapy partnership - Pharmaceutical Technology



GRIT and Quangang announce IL-2 T-cell therapy partnership  Pharmaceutical Technology

Cleanup on IL-2 - Science | AAAS



Cleanup on IL-2  Science | AAAS

FIGURE 4. IL-2 mutein binds preferentially to Treg cells releasing Treg... - ResearchGate



FIGURE 4. IL-2 mutein binds preferentially to Treg cells releasing Treg...  ResearchGate

IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines - PNAS



IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines  PNAS

Fig. 1. IL-2 receptor structure and signaling. IL-2 binds to the IL-2Rα... - ResearchGate



Fig. 1. IL-2 receptor structure and signaling. IL-2 binds to the IL-2Rα...  ResearchGate

Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen - Front...



Nanoparticles loaded with IL-2 and TGF-β promote transplantation tolerance to alloantigen  Frontiers

The Blockade of Interleukin-2 During the Acute Phase of Trypanosoma cruzi Infection Reveals Its D...



The Blockade of Interleukin-2 During the Acute Phase of Trypanosoma cruzi Infection Reveals Its Dominant Regulatory Role  Frontiers

Figure 1. Interleukin-2 (IL-2) production, epitopes, and receptors.... - ResearchGate



Figure 1. Interleukin-2 (IL-2) production, epitopes, and receptors....  ResearchGate

FIG. 4. Increased IL-2 production and T-cell proliferation in... - ResearchGate



FIG. 4. Increased IL-2 production and T-cell proliferation in...  ResearchGate

Synthekine nabs $100M to boost IL-2 programs after rivals hit setbacks - Endpoints News



Synthekine nabs $100M to boost IL-2 programs after rivals hit setbacks  Endpoints News

Novel IL-2 Agent Shows Promise in Advanced Solid Tumors - MedPage Today



Novel IL-2 Agent Shows Promise in Advanced Solid Tumors  MedPage Today

Dual role of IL-2 signaling mediated by different IL-2 receptor... - ResearchGate



Dual role of IL-2 signaling mediated by different IL-2 receptor...  ResearchGate

ESMO Virtual Plenary: Ph I trial of PD-1/IL-2 BsAb in pts with advanced cancer - ESMO



ESMO Virtual Plenary: Ph I trial of PD-1/IL-2 BsAb in pts with advanced cancer  ESMO

IL-2 Program Profits With Bonum's Drs. John Mulligan And Neela Patel - Life Science Leader



IL-2 Program Profits With Bonum's Drs. John Mulligan And Neela Patel  Life Science Leader

Fig. 2. Increases in Tregs after single dose in vivo IL-2 treatments.... - ResearchGate



Fig. 2. Increases in Tregs after single dose in vivo IL-2 treatments....  ResearchGate

Figure 4. IL-2-REH selectively promotes signaling in Tregs with reduced... - ResearchGate



Figure 4. IL-2-REH selectively promotes signaling in Tregs with reduced...  ResearchGate

FIGURE 5. IL-2 secretion is required for enhanced STAT5 activation and... - ResearchGate



FIGURE 5. IL-2 secretion is required for enhanced STAT5 activation and...  ResearchGate

Figure 2. IL-2 dose-dependent receptor response. In steady state low to... - ResearchGate



Figure 2. IL-2 dose-dependent receptor response. In steady state low to...  ResearchGate

IL-2 Series To Produce New Game Based On The Korean War - Bleeding Cool News



IL-2 Series To Produce New Game Based On The Korean War  Bleeding Cool News

Figure 1: IL-2 signals program CD8+ T cells for secondary population... - ResearchGate



Figure 1: IL-2 signals program CD8+ T cells for secondary population...  ResearchGate

Figure 4. In vitro NK proliferation (A) IL-2 consumption by T cells was... - ResearchGate



Figure 4. In vitro NK proliferation (A) IL-2 consumption by T cells was...  ResearchGate

Soluble Interleukin-2 Receptor Level as a Marker of Hemophagocytic Lymphohistiocytosis in Childre...



Soluble Interleukin-2 Receptor Level as a Marker of Hemophagocytic Lymphohistiocytosis in Children With Severe Dengue  Frontiers

Interleukin-2 Mediated Expansion of T-Regulatory Cells as an Ischemic Stroke Therapy - American H...



Interleukin-2 Mediated Expansion of T-Regulatory Cells as an Ischemic Stroke Therapy  American Heart Association Journals

Signaling through IL-2 receptor (IL-2R) pathway. IL-2 exerts its... - ResearchGate



Signaling through IL-2 receptor (IL-2R) pathway. IL-2 exerts its...  ResearchGate

Pros and cons of high dose (HD) interleukin-2 (IL-2) therapy for... - ResearchGate



Pros and cons of high dose (HD) interleukin-2 (IL-2) therapy for...  ResearchGate

A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses...



A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis  Frontiers

Novel approaches for IL-2 based cancer immunotherapy. Various... - ResearchGate



Novel approaches for IL-2 based cancer immunotherapy. Various...  ResearchGate

Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA ...



Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70  Science | AAAS

Effect of Low-dose IL-2 on T cell activation and proliferation in the... - ResearchGate



Effect of Low-dose IL-2 on T cell activation and proliferation in the...  ResearchGate

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature



PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function  Nature

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JC...



A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models  JCI.org

Korea. IL-2 Series - Official Reveal Trailer - IGN



Korea. IL-2 Series - Official Reveal Trailer  IGN

IL-6 mediates the IL-2 responsiveness of Tfh cells. In the presence of... - ResearchGate



IL-6 mediates the IL-2 responsiveness of Tfh cells. In the presence of...  ResearchGate

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes - Sci...



Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes  Science | AAAS

IL-2- and Blimp-1-Dependent Effector CD8 + T Cell Differentiation - ResearchGate



IL-2- and Blimp-1-Dependent Effector CD8 + T Cell Differentiation  ResearchGate

Overcoming toxicities: are IL-2 smart cytokines the next big thing? - Labiotech.eu



Overcoming toxicities: are IL-2 smart cytokines the next big thing?  Labiotech.eu

Signaling network of the IL-2 cytokine family. Receptors of IL-2,... - ResearchGate



Signaling network of the IL-2 cytokine family. Receptors of IL-2,...  ResearchGate

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature



PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program  Nature