"il-2" の関連情報検索結果
In Silico tool for predicting, designing and scanning IL-2 inducing peptides | Scientific Reports...

In Silico tool for predicting, designing and scanning IL-2 inducing peptides | Scientific Reports Nature
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals - ...

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals Science | AAAS
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, dou...

Medicenna Therapeutics Reports Second Quarter Fiscal 2026 Financial Results and Provides a Corpor...

Medicenna Therapeutics Reports Second Quarter Fiscal 2026 Financial Results and Provides a Corporate Update GlobeNewswire
2 Babies Sickened In IL, Parents Warned Not To Use Recalled Baby Formula Amid Botulism Outbreak -...

2 Babies Sickened In IL, Parents Warned Not To Use Recalled Baby Formula Amid Botulism Outbreak Patch
Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial - FirstWor...

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial FirstWord Pharma
Adding low-dose IL-2 to riluzole may improve survival in ALS - ALS News Today

Adding low-dose IL-2 to riluzole may improve survival in ALS ALS News Today
Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alter...

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alternatives Fierce Biotech
IL-2 and IL-15 augment HBV therapeutic vaccination and PD1 blockade for functional cure in the AA...

FDA Clears IND for GL-IL2-138 in Cancer and Beyond - Targeted Oncology

FDA Clears IND for GL-IL2-138 in Cancer and Beyond Targeted Oncology
PD-1 + IL-2 power couple: Wake up 'sleepy' T cells to turbo-charge cancer cures - EurekAlert!

PD-1 + IL-2 power couple: Wake up 'sleepy' T cells to turbo-charge cancer cures EurekAlert!
Reshape the Fates of Treg and CD8+T Cells Through IL-2Rα by Synergizing Divergent Receptor-Biased...

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion | Nature Com...

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentia...

Coordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy Science | AAAS
Examining the evidence for IL-2 in amyotrophic lateral sclerosis - The Lancet

Examining the evidence for IL-2 in amyotrophic lateral sclerosis The Lancet
Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune respons...

Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response Nature
An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammat...

Expression of an interleukin-2 partial agonist enhances regulatory T cell persistence and efficac...

Biomineral tablets for long-acting IL-2 immunotherapy - Nature

Biomineral tablets for long-acting IL-2 immunotherapy Nature
CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communic...

Low-Dose Interleukin-2 Reduces Proinflammatory Biomarkers in Phase 2 Study of Alzheimer Disease -...

Low-Dose Interleukin-2 Reduces Proinflammatory Biomarkers in Phase 2 Study of Alzheimer Disease Neurology Live
A glimpse into the application of the immunomodulatory effect of IL-2 in systemic lupus erythemat...

National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik - Vintage Aviatio...

National Air and Space Museum Completes Restoration of Ilyushin Il-2 Shturmovik Vintage Aviation News
Interleukin-2 Inhibitors Clinical Trial Pipeline Accelerates as 20+ Pharma Companies Rigorously D...

Based on the immune system: the role of the IL-2 family in pancreatic disease - Frontiers

Based on the immune system: the role of the IL-2 family in pancreatic disease Frontiers
Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complicatio...

WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game - DualShockers

WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game DualShockers
Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network - ScienceDirec...

Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network ScienceDirect.com
Engineered IL-2 molecule shows promise in treating autoimmune disease - healthenews.mcgill.ca

Engineered IL-2 molecule shows promise in treating autoimmune disease healthenews.mcgill.ca
IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers

IL-2 based cancer immunotherapies: an evolving paradigm Frontiers
Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothe...

Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function Nature
Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor ...

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor PNAS
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program Nature
Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and...

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells - Nature

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells Nature
Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses - Frontiers

Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses Frontiers
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy -...

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy Nature
Engineering IL-2 for immunotherapy of autoimmunity and cancer - Nature

Engineering IL-2 for immunotherapy of autoimmunity and cancer Nature
A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T ...

De novo design of potent and selective mimics of IL-2 and IL-15 - Nature

De novo design of potent and selective mimics of IL-2 and IL-15 Nature
An engineered IL-2 partial agonist promotes CD8+ T cell stemness - Nature

An engineered IL-2 partial agonist promotes CD8+ T cell stemness Nature
An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity...

An IL-2 mutein engineered to promote expansion of regulatory T cells arrests ongoing autoimmunity in mice Science | AAAS
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulator...

CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus - Science | AAAS

CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus Science | AAAS
Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 - Na...

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 Nature
T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes - Nature

T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes Nature
An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism - Nature

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism Nature
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes - Sci...

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes Science | AAAS
Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulatio...

A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in...

A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia Science | AAAS
Regulatory T cells control toxicity in a humanized model of IL-2 therapy - Nature

Regulatory T cells control toxicity in a humanized model of IL-2 therapy Nature
Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates ...

Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain p...

Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung...

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue...

Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue Nature
A promising option for unremitting ulcerative colitis: Low-dose IL-2 - Boston Children's Answers

A promising option for unremitting ulcerative colitis: Low-dose IL-2 Boston Children's Answers
Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People wi...

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People with Systemic Lupus Erythematosus Lupus Foundation of America
A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 - Nature

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 Nature
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helpe...

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells Science | AAAS
Dynamically modeling the effective range of IL-2 dosage in the treatment of systemic lupus erythe...

Dynamically modeling the effective range of IL-2 dosage in the treatment of systemic lupus erythematosus ScienceDirect.com
Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases - Frontiers

Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases Frontiers
BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Can...

BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Cancer UroToday
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor ...

An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer - Nature

An IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer Nature
Revealing the significance of IL-2 and IL-5 in SARS-CoV-2-specific T-cell responses in kidney tra...

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo ...

A novel human IL-2 mutein with minimal systemic toxicity exerts greater antitumor efficacy than w...

Managing Toxicities of High-Dose Interleukin-2 - CancerNetwork

Managing Toxicities of High-Dose Interleukin-2 CancerNetwork
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism - N...

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism Nature
Restoring IL-2 to its cancer immunotherapy glory - Nature

A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism - Nature

A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism Nature
Efficacy and antitumor activity of a mutant type of interleukin 2 - Nature

Efficacy and antitumor activity of a mutant type of interleukin 2 Nature
T cell antitumor immunity by targeting IL-2 receptor signaling - Nature

T cell antitumor immunity by targeting IL-2 receptor signaling Nature
IL-2 Signaling Axis Defects: How Many Faces? - Frontiers

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics Nature
Why measure soluble interleukin-2 receptor levels? - News-Medical

Why measure soluble interleukin-2 receptor levels? News-Medical
T cell receptor and IL-2 signaling strength control memory CD8 - Nature

T cell receptor and IL-2 signaling strength control memory CD8 Nature
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells - Nature

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells Nature
Overcoming toxicities: are IL-2 smart cytokines the next big thing? - Labiotech.eu

Overcoming toxicities: are IL-2 smart cytokines the next big thing? Labiotech.eu
An essential role for the IL-2 receptor in T - Nature

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T - Nature

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T Nature
Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity - Nature

Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity Nature
Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal o...

Lifileucel Induces Response in Metastatic Melanoma Independent of Number of IL-2 Doses Received -...

Lifileucel Induces Response in Metastatic Melanoma Independent of Number of IL-2 Doses Received OncLive
Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of ...

A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for p...

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 - Nature

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 Nature
The Potential of Harnessing IL-2-Mediated Immunosuppression to Prevent Pathogenic B Cell Response...

The Potential of Harnessing IL-2-Mediated Immunosuppression to Prevent Pathogenic B Cell Responses Frontiers
The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse mod...

The effects of low-dose IL-2 on Th17/Treg cell imbalance in primary biliary cholangitis mouse models BMC Gastroenterology
Implanted “Drug Factories” Deliver Cancer Treatment Directly to Tumors - National Cancer Institut...

Implanted “Drug Factories” Deliver Cancer Treatment Directly to Tumors National Cancer Institute (.gov)
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice - PNAS

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice PNAS
Synthetic cytokine circuits that drive T cells into immune-excluded tumors - Science | AAAS

Synthetic cytokine circuits that drive T cells into immune-excluded tumors Science | AAAS
Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids - PNAS

Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids PNAS
The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity ...

The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity Wiley Online Library
IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repress...

IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repression Nature
Targeting systemic IL-2 to BCMA CAR-T cells - Nature

Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma - OncLive

Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma OncLive
Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy - OncLive

Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy OncLive