"il2" の関連情報検索結果
Therapeutic activity of F8-IL2 immunocytokine in combination with... - researchgate.net

Therapeutic activity of F8-IL2 immunocytokine in combination with... researchgate.net
TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion | Nature Com...

A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-media...

A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies ScienceDirect.com
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals - ...

A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals Science | AAAS
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, dou...

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial - FirstWor...

Nektar says IL-2 pathway agonist rejected by Lilly succeeds in atopic dermatitis trial FirstWord Pharma
Claude on Google Cloud’s Vertex AI: FedRAMP High and IL2 Authorized - Anthropic

Claude on Google Cloud’s Vertex AI: FedRAMP High and IL2 Authorized Anthropic
Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in pat...

Abstract 4144964: Low-Dose IL-2 Lowers Arterial Inflammation and Trends Towards Lower MACE in patients with ACS: The results of the IVORY trial and IVORY FINALE study American Heart Association Journals
AWT020: a novel fusion protein harnessing PD-1 blockade and selective IL-2 Cis-activation for enh...

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alter...

Mural risks going to the wall as IL-2 flop triggers 90% staff reduction, hunt for strategic alternatives Fierce Biotech
Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics wit...

Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity ScienceDirect.com
CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation | Nature Communic...

Examining the evidence for IL-2 in amyotrophic lateral sclerosis - The Lancet

Examining the evidence for IL-2 in amyotrophic lateral sclerosis The Lancet
In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell e...

In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy ScienceDirect.com
An in situ engineered chimeric IL-2 receptor potentiates the tumoricidal activity of proinflammat...

An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to...

An IL-2 mutein increases regulatory T cell suppression of dendritic cells via IL-10 and CTLA-4 to promote T cell anergy ScienceDirect.com
Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune respons...

Long-acting IL-2 release from pressure-fused biomineral tablets promotes antitumor immune response Nature
Harnessing IL-2 for immunotherapy against cancer and chronic infection: a historical perspective ...

Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 ove...

Biomineral tablets for long-acting IL-2 immunotherapy - Nature

Biomineral tablets for long-acting IL-2 immunotherapy Nature
A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells agains...

A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma Science | AAAS
Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T - Nature

Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T Nature
Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emi...

Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography ScienceDirect.com
Targeting systemic IL-2 to BCMA CAR-T cells - Nature

Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy - OncLive

Early Serum IL-2 Levels Are Associated With CAR T-Cell Expansion Post–CAR T-Cell Therapy OncLive
Adding low-dose IL-2 to riluzole may improve survival in ALS - ALS News Today

Adding low-dose IL-2 to riluzole may improve survival in ALS ALS News Today
WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game - DualShockers

WW2 Flight Sim Il-2 Sturmovik Announces Final Expansion Before New Korea Game DualShockers
Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People wi...

Scientists Identify Key Biomarkers That May Predict Low-Dose IL-2 Treatment Efficacy in People with Systemic Lupus Erythematosus Lupus Foundation of America
BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Can...

BCANTT 2024: Rationally Engineered IL2 for Enhanced Treatment of Local and Metastatic Bladder Cancer UroToday
Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing...

Human serum albumin promotes interactions between HSA-IL-2 fusion protein and CD122 for enhancing immunotherapy ScienceDirect.com
Teva's Breakthrough Cancer Immunotherapy Gains Momentum with Major Asian Market Partnership - Sto...

Teva's Breakthrough Cancer Immunotherapy Gains Momentum with Major Asian Market Partnership Stock Titan
IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines - PNAS

IL-2/anti-IL-2 antibody complexes augment immune responses to therapeutic cancer vaccines PNAS
Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network - ScienceDirec...

Regulating IL-2 Immune Signaling Function Via A Core Allosteric Structural Network ScienceDirect.com
IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in mouse colon cancer - ScienceD...

IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in mouse colon cancer ScienceDirect.com
IL-2 Sturmovik Flying Circus Vol. IV Released - FSElite

Based on the immune system: the role of the IL-2 family in pancreatic disease - Frontiers

Based on the immune system: the role of the IL-2 family in pancreatic disease Frontiers
IL-2 Complexed With Anti–IL-2 Antibody Expands the Maternal T-Regulatory Cell Pool and Alleviates...

IL-2 Complexed With Anti–IL-2 Antibody Expands the Maternal T-Regulatory Cell Pool and Alleviates Fetal Loss in Abortion-Prone Mice ScienceDirect.com
Novel engineered IL-2 Nemvaleukin alfa combined with PD1 checkpoint blockade enhances the systemi...

Novel engineered IL-2 Nemvaleukin alfa combined with PD1 checkpoint blockade enhances the systemic anti-tumor responses of radiation therapy Journal of Experimental & Clinical Cancer Research
T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics - ...

T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics Nature
Worst Piloting Fails and Mishaps IL2 Sturmovik BoS - MSN

Engineered IL-2 molecule shows promise in treating autoimmune disease - McGill University

Engineered IL-2 molecule shows promise in treating autoimmune disease McGill University
Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs - MyStateline

Development at Rockford’s US-20 and IL-2 interchange could soon bring 37,000 jobs MyStateline
Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T ...

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation - Science...

Novel design of potent anti-tumour activity of IL-2 prodrug by FAPα-mediated activation ScienceDirect.com
IL-2 based cancer immunotherapies: an evolving paradigm - Frontiers

IL-2 based cancer immunotherapies: an evolving paradigm Frontiers
Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strateg...

Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies Molecular Cancer
A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models - JC...

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models JCI - Welcome
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program - Nature

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program Nature
A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for p...

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor ...

Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor PNAS
The scFv-IL2 fusion protein maintains the functions of both component proteins. - researchgate.net

The scFv-IL2 fusion protein maintains the functions of both component proteins. researchgate.net
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy -...

A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy Nature
Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T c...

Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity Journal of Biomedical Science
PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function - Nature

PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function Nature
IL-2 immunotherapy for targeting regulatory T cells in autoimmunity - Genes & Immunity - Nature

IL-2 immunotherapy for targeting regulatory T cells in autoimmunity - Genes & Immunity Nature
Emerging mechanisms and applications of low-dose IL-2 therapy in autoimmunity - ScienceDirect.com

Emerging mechanisms and applications of low-dose IL-2 therapy in autoimmunity ScienceDirect.com
IL-2 treatment can be dangerous. Here’s how drug firms are trying to fix it - C&EN

IL-2 treatment can be dangerous. Here’s how drug firms are trying to fix it C&EN
Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells ef...

Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions ScienceDirect.com
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2...

An engineered IL-2 partial agonist promotes CD8+ T cell stemness - Nature

An engineered IL-2 partial agonist promotes CD8+ T cell stemness Nature
De novo design of potent and selective mimics of IL-2 and IL-15 - Nature

De novo design of potent and selective mimics of IL-2 and IL-15 Nature
Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling - EMBO P...

Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling EMBO Press
IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity ...

IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma ScienceDirect.com
Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy - Nature

Engineered E. coli Nissle 1917 for delivery of bioactive IL-2 for cancer immunotherapy Nature
Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and...

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes - Sci...

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes Science | AAAS
T cell exhaustion by activating the aryl hydrocarbon receptor - Nature

T cell exhaustion by activating the aryl hydrocarbon receptor Nature
An essential role for the IL-2 receptor in T - Nature

IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function - Sci...

IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function ScienceDirect.com
Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulatio...

The antitumor effect induced by an IL-2 ‘no-alpha’ mutein depends on changes in the CD8 - Frontiers

The antitumor effect induced by an IL-2 ‘no-alpha’ mutein depends on changes in the CD8 Frontiers
A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T ...

Biology and regulation of IL-2: from molecular mechanisms to human therapy - Nature

Biology and regulation of IL-2: from molecular mechanisms to human therapy Nature
Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive...

Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment ScienceDirect.com
A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 - Nature

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 Nature
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist...

Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist Nature
A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo ...

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 - Na...

Measurement of IFN-γ and IL-2 for the assessment of the cellular immunity against SARS-CoV-2 Nature
Selective delivery of low-affinity IL-2 to PD-1+ T cells rejuvenates antitumor immunity with redu...

Selective delivery of low-affinity IL-2 to PD-1+ T cells rejuvenates antitumor immunity with reduced toxicity JCI - Welcome
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 - Nature

IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8 Nature
T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes - Nature

T cell frequency and induces anti-inflammatory gene expression in type 1 diabetes Nature
Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helpe...

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells Science | AAAS
Engineering IL-2 for immunotherapy of autoimmunity and cancer - Nature

Engineering IL-2 for immunotherapy of autoimmunity and cancer Nature
Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using ...

Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases - Frontiers

Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases Frontiers
Membrane-bound IL-2 improves the expansion, survival, and phenotype of CAR Tregs and confers resi...

Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung...

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism - N...

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism Nature
Lifileucel Induces Response in Metastatic Melanoma Independent of Number of IL-2 Doses Received -...

Lifileucel Induces Response in Metastatic Melanoma Independent of Number of IL-2 Doses Received OncLive
Salmonella-IL2 May Improve Upon FOLFIRINOX in Stage IV Pancreatic Cancer - Cancer Therapy Advisor

Salmonella-IL2 May Improve Upon FOLFIRINOX in Stage IV Pancreatic Cancer Cancer Therapy Advisor
An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism - Nature

An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism Nature
Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells - Nature

Low-dose IL-2 enhances the generation of IL-10-producing immunoregulatory B cells Nature
Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act - Frontiers

Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act Frontiers
IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repress...

IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repression Nature
IL2 Sturmovik guide: how to play IL2 Battle of Stalingrad - wargamer.com

IL2 Sturmovik guide: how to play IL2 Battle of Stalingrad wargamer.com
Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma - OncLive

Dr Olson on Toxicities Associated With Lifileucel and IL-2 in Melanoma OncLive
cAMP response element modulator α controls IL2 and IL17A expression during CD4 lineage commitment...

A novel human IL-2 mutein with minimal systemic toxicity exerts greater antitumor efficacy than w...

A DNA vaccine (EG95-PT1/2/3-IL2) encoding multi-epitope antigen and IL-2 provokes efficient and l...

A DNA vaccine (EG95-PT1/2/3-IL2) encoding multi-epitope antigen and IL-2 provokes efficient and long-term immunity to echinococcosis ScienceDirect.com
Selective activation and expansion of regulatory T cells using lipid encapsulated mRNA encoding a...
