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Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosynthesis in Artemisia...



Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosynthesis in Artemisia annua glandular trichomes  Nature

‘Music To Our Ears’: A New Malaria Treatment May Offer Long-Awaited Alternative to Artemisinin - ...



‘Music To Our Ears’: A New Malaria Treatment May Offer Long-Awaited Alternative to Artemisinin  Global Health NOW

Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury t...



Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury to lung cancer  Frontiers

Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resis...



Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance  Science | AAAS

Development and evaluation of novel zein-based artemisinin sustained-release formulation for trea...



Development and evaluation of novel zein-based artemisinin sustained-release formulation for treating drug-resistant malaria  ASM Journals

Artemisinin sensitizes triple negative breast cancer to immune checkpoint therapy through suppres...



Artemisinin sensitizes triple negative breast cancer to immune checkpoint therapy through suppressing KEAP1-mediated PD-L1 degradation  ScienceDirect.com

Severe Plasmodium falciparum Malaria Complicated by Post-artemisinin Delayed Hemolysis in a Non-i...



Severe Plasmodium falciparum Malaria Complicated by Post-artemisinin Delayed Hemolysis in a Non-immune Pediatric Returning Traveler  Cureus

PfPI3K inhibition reversed artemisinin resistance by increasing ROS and ubiquitinated protein lev...



PfPI3K inhibition reversed artemisinin resistance by increasing ROS and ubiquitinated protein levels in Plasmodium falciparum  Nature

Artemisinin exerts antidepressant-like effects via activation of AKT and ERK signaling pathways -...



Artemisinin exerts antidepressant-like effects via activation of AKT and ERK signaling pathways  Frontiers

Rebalancing the inflammatory trajectory from inflammatory bowel disease to colitis-associated col...



Rebalancing the inflammatory trajectory from inflammatory bowel disease to colitis-associated colorectal cancer via artemisinin-based multitarget therapy | Acta Pharmacologica Sinica  Nature

An improved artemisinin algorithm for task allocation in heterogeneous robot systems for chemical...



An improved artemisinin algorithm for task allocation in heterogeneous robot systems for chemical inspection  Nature

Fluorescence-based bioassay for the detection of changes in mitochondrial physiology during artem...



Fluorescence-based bioassay for the detection of changes in mitochondrial physiology during artemisinin-induced growth arrest of blood-stage Plasmodium falciparum  Nature

Differential effects of biologically and chemically synthesized copper oxide nanoparticles on art...



Differential effects of biologically and chemically synthesized copper oxide nanoparticles on artemisinin biosynthesis gene expression in Artemisia absinthium  Nature

Engineered elicitation in Artemisia annua L. callus cultures alters artemisinin biosynthesis, ant...



Engineered elicitation in Artemisia annua L. callus cultures alters artemisinin biosynthesis, antioxidant responses, and bioactivity  Nature

Epigenetically conferred ring-stage survival in Plasmodium falciparum against artemisinin treatme...



Epigenetically conferred ring-stage survival in Plasmodium falciparum against artemisinin treatment  Nature

The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and ...



The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and induces autophagy and apoptosis in cancer cells  Nature

Serial cross-sectional school surveys identifies C469Y, P553L, R561H and A675V kelch 13 mutations...



Serial cross-sectional school surveys identifies C469Y, P553L, R561H and A675V kelch 13 mutations associated with artemisinin resistance in Western Kenya  Nature

Rising prevalence of Plasmodium falciparum Artemisinin partial resistance mutations in Ethiopia -...



Rising prevalence of Plasmodium falciparum Artemisinin partial resistance mutations in Ethiopia  Nature

Artemisinin derivatives differently affect cell death of lung cancer subtypes by regulating GPX4 ...



Artemisinin derivatives differently affect cell death of lung cancer subtypes by regulating GPX4 in patient-derived tissue cultures  Nature

Novel Cyano-Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Trea...



Novel Cyano-Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment  Wiley

Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis - N...



Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis  Nature

Global Malaria Threat Deepens As Drug Resistance Rises - Health Policy Watch



Global Malaria Threat Deepens As Drug Resistance Rises  Health Policy Watch

How is Asia-like artemisinin resistance emerging in Africa? - The Hindu



How is Asia-like artemisinin resistance emerging in Africa?  The Hindu

Scientists Combine Antimalarial Drug with Light-Sensitive Molecules for Promising Treatment of Ca...



Scientists Combine Antimalarial Drug with Light-Sensitive Molecules for Promising Treatment of Cancer  Lab Manager

Diversifying antimalarial treatment for uncomplicated Plasmodium falciparum malaria in Uganda - T...



Diversifying antimalarial treatment for uncomplicated Plasmodium falciparum malaria in Uganda  The Lancet

Artemisinin Combination Therapy (ACT) Market Size, Share & Growth Report by 2034 - Straits Research



Artemisinin Combination Therapy (ACT) Market Size, Share & Growth Report by 2034  Straits Research

Nick White, 1951-2026 - wellcome.org



Nick White, 1951-2026  wellcome.org

Reconsidering the clinical assessment of resistance to slowly eliminated antimalarial drugs in hi...



Reconsidering the clinical assessment of resistance to slowly eliminated antimalarial drugs in high-transmission settings  The Lancet

New tools saved a million lives from malaria last year but progress under threat as drug resistan...



New tools saved a million lives from malaria last year but progress under threat as drug resistance rises  World Health Organization (WHO)

Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance ...



Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance in Plasmodium berghei K173 based on targeted metabolomics  Nature

Researchers find signs of regional spread of drug-resistant malaria in Africa - CIDRAP



Researchers find signs of regional spread of drug-resistant malaria in Africa  CIDRAP

Demand for Artemisinin Combination Therapy in UK | Global Market Analysis Report - 2036 - Fact.MR



Demand for Artemisinin Combination Therapy in UK | Global Market Analysis Report - 2036  Fact.MR

World malaria report 2025 - World Health Organization (WHO)



World malaria report 2025  World Health Organization (WHO)

Artemisinin-resistant malaria in Africa demands urgent action - Science | AAAS



Artemisinin-resistant malaria in Africa demands urgent action  Science | AAAS

Evidence of Artemisinin-Resistant Malaria in Africa - The New England Journal of Medicine



Evidence of Artemisinin-Resistant Malaria in Africa  The New England Journal of Medicine

African health leaders and global partners unite to confront rising threat of antimalarial drug r...



African health leaders and global partners unite to confront rising threat of antimalarial drug resistance  World Health Organization (WHO)

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome - Nature



Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome  Nature

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea - The New England...



Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea  The New England Journal of Medicine

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodi...



Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum  Nature

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum - ...



tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum  Nature

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R5...



Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda  Nature

Still time to contain artemisinin resistance in Africa - The Lancet



Still time to contain artemisinin resistance in Africa  The Lancet

From malaria fighter to diabetes guardian: the emerging role of artesunate in treating diabetes a...



From malaria fighter to diabetes guardian: the emerging role of artesunate in treating diabetes and diabetic complications  Frontiers

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near co...



Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania  Nature

Nutrient Limitation Mimics Artemisinin Tolerance in Malaria - ASM Journals



Nutrient Limitation Mimics Artemisinin Tolerance in Malaria  ASM Journals

Preventing antimalarial drug resistance with triple artemisinin-based combination therapies - Nature



Preventing antimalarial drug resistance with triple artemisinin-based combination therapies  Nature

Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1 - Nature



Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1  Nature

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initia...



Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response  Nature

Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa - The New England Journal of M...



Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa  The New England Journal of Medicine

Modeling policy interventions for slowing the spread of artemisinin-resistant pfkelch R561H mutat...



Modeling policy interventions for slowing the spread of artemisinin-resistant pfkelch R561H mutations in Rwanda  Nature

Continuous innovation needed to eliminate malaria - Gates Foundation



Continuous innovation needed to eliminate malaria  Gates Foundation

Photoaffinity probe-based antimalarial target identification of artemisinin in the intraerythrocy...



Photoaffinity probe-based antimalarial target identification of artemisinin in the intraerythrocytic developmental cycle of Plasmodium falciparum  Wiley Online Library

Four Artemisinin-Based Treatments in African Pregnant Women with Malaria - The New England Journa...



Four Artemisinin-Based Treatments in African Pregnant Women with Malaria  The New England Journal of Medicine

Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular marke...



Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular markers of resistance  The Lancet

Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB...



Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB-1 signaling pathway  Nature

Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria para...



Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa  Nature

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis | Cell...



Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis | Cell Death & Differentiation  Nature

Artemisinin Drug, Discovery, Targets, Latest News - Vajiram & Ravi



Artemisinin Drug, Discovery, Targets, Latest News  Vajiram & Ravi

The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background ...



The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background  Nature

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia - Nature



Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia  Nature

Genetic architecture of artemisinin-resistant Plasmodium falciparum - Nature



Genetic architecture of artemisinin-resistant Plasmodium falciparum  Nature

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic p...



Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic program to enhance survival  Nature

DNA binding by the antimalarial compound artemisinin - Nature



DNA binding by the antimalarial compound artemisinin  Nature

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa - The New England J...



Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa  The New England Journal of Medicine

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility - Nature



Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility  Nature

The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression ...



The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment  Nature

The Threat of Artemisinin-Resistant Malaria - The New England Journal of Medicine



The Threat of Artemisinin-Resistant Malaria  The New England Journal of Medicine

Expression of key genes affecting artemisinin content in five Artemisia species - Nature



Expression of key genes affecting artemisinin content in five Artemisia species  Nature

The emergence of artemisinin partial resistance in Africa: how do we respond? - The Lancet



The emergence of artemisinin partial resistance in Africa: how do we respond?  The Lancet

Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemi...



Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis  The Lancet

Trio fluorophore-based phenotypic assay for the detection of artemisinin-induced growth-arrested ...



Trio fluorophore-based phenotypic assay for the detection of artemisinin-induced growth-arrested Plasmodium falciparum in human erythrocytes  Nature

Multiple first-line therapies as part of the response to antimalarial drug resistance - World Hea...



Multiple first-line therapies as part of the response to antimalarial drug resistance  World Health Organization (WHO)

Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding ...



Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding affinity and decreased artemisinin activation  Nature

Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 an...



Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 and Pfcoronin molecular markers in treatment failure in Senegal  Nature

Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release - ...



Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release  Nature

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum - Nature



Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum  Nature

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylprop...



Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua  Nature

Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India - The New Englan...



Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India  The New England Journal of Medicine

Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new fro...



Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new frontier in chemotherapeutic efficacy and cancer therapy  Nature

Safety of artemisinin and non-artemisinin antimalarials in the first trimester of pregnancy - Wor...



Safety of artemisinin and non-artemisinin antimalarials in the first trimester of pregnancy  World Health Organization (WHO)

The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular qui...



The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular quiescence/senescence and drug resilience  Nature

Cancer combination therapies with artemisinin-type drugs - ScienceDirect.com



Cancer combination therapies with artemisinin-type drugs  ScienceDirect.com

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite - Nature



The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite  Nature

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover ...



Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background  Nature

50 years of artemisinin - Chemistry World



50 years of artemisinin  Chemistry World

Artemisinin resistance and malaria elimination: Where are we now? - Frontiers



Artemisinin resistance and malaria elimination: Where are we now?  Frontiers

Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis - ...



Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis  Frontiers

Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin - ...



Approaches and Recent Developments for the Commercial Production of Semi-synthetic Artemisinin  Frontiers

Artemisinin Resistance in Plasmodium falciparum Malaria - The New England Journal of Medicine



Artemisinin Resistance in Plasmodium falciparum Malaria  The New England Journal of Medicine

Population coverage of artemisinin-based combination treatment in children younger than 5 years w...



Population coverage of artemisinin-based combination treatment in children younger than 5 years with fever and Plasmodium falciparum infection in Africa, 2003–2015: a modelling study using data from national surveys  The Lancet

Artemisinin-Resistant Malaria in Asia - The New England Journal of Medicine



Artemisinin-Resistant Malaria in Asia  The New England Journal of Medicine

The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune dise...



The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases  Wiley Online Library

RNAi down-regulation of cinnamate-4-hydroxylase increases artemisinin biosynthesis in Artemisia a...



RNAi down-regulation of cinnamate-4-hydroxylase increases artemisinin biosynthesis in Artemisia annua  Nature

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites - Scie...



A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites  Science | AAAS

Elevation of artemisinin content by co-transformation of artemisinin biosynthetic pathway genes a...



Elevation of artemisinin content by co-transformation of artemisinin biosynthetic pathway genes and trichome-specific transcription factors in Artemisia annua  Frontiers

Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda - The New England ...



Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda  The New England Journal of Medicine

High-level semi-synthetic production of the potent antimalarial artemisinin - Nature



High-level semi-synthetic production of the potent antimalarial artemisinin  Nature

Manus gets funds to develop the antimalarial artemisinin - C&EN



Manus gets funds to develop the antimalarial artemisinin  C&EN

Artemisinin Derivatives and Synthetic Trioxane Trigger Apoptotic Cell Death in Asexual Stages of ...



Artemisinin Derivatives and Synthetic Trioxane Trigger Apoptotic Cell Death in Asexual Stages of Plasmodium  Frontiers

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria - Nature



A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria  Nature