Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis - N...

Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis  Nature

Antimalarial drug artemisinin stabilizes PfRACK1 binding to the ribosome - ScienceDirect.com

Antimalarial drug artemisinin stabilizes PfRACK1 binding to the ribosome  ScienceDirect.com

Mechanistic Insights into the Nonenzymatic Biosynthesis of Artemisinin and Related Natural Produc...

Mechanistic Insights into the Nonenzymatic Biosynthesis of Artemisinin and Related Natural Products: A Quantum Chemical Study  ACS Publications

TU YOUYOU - NobelPrize.org

TU YOUYOU  NobelPrize.org

Novel Cyano-Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Trea...

Novel Cyano-Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment  Wiley

Artemisinin derivatives differently affect cell death of lung cancer subtypes by regulating GPX4 ...

Artemisinin derivatives differently affect cell death of lung cancer subtypes by regulating GPX4 in patient-derived tissue cultures  Nature

Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor ...

Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid  ACS Publications

The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and ...

The novel amino-artemisinin derivative WHN-11 disrupts mitochondria and protein homeostasis, and induces autophagy and apoptosis in cancer cells  Nature

Discovery of D-Ring-Contracted Artemisinin as a Potent Hydrophobic Tag for Targeted Protein Degra...

Discovery of D-Ring-Contracted Artemisinin as a Potent Hydrophobic Tag for Targeted Protein Degradation  ACS Publications

Artemisinin alleviates astrocyte overactivation and neuroinflammation by modulating the IRE1/NF-κ...

Artemisinin alleviates astrocyte overactivation and neuroinflammation by modulating the IRE1/NF-κB signaling pathway in in vitro and in vivo Alzheimer's disease models  ScienceDirect.com

Rising prevalence of Plasmodium falciparum Artemisinin partial resistance mutations in Ethiopia -...

Rising prevalence of Plasmodium falciparum Artemisinin partial resistance mutations in Ethiopia  Nature

Artemisinin synergizes with CCCP in autophagic cell death induction via ER stress in uveal melano...

Artemisinin synergizes with CCCP in autophagic cell death induction via ER stress in uveal melanoma  ScienceDirect.com

Artemisinin alleviates cisplatin-induced damage in GC-1 spermatogonia through ER stress mechanism...

Artemisinin alleviates cisplatin-induced damage in GC-1 spermatogonia through ER stress mechanisms  ScienceDirect.com

The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression ...

The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment  Nature

Anti-tumor effects of artemisinin-based oligomers: From monomer to trimer as a novel drug-enhanci...

Anti-tumor effects of artemisinin-based oligomers: From monomer to trimer as a novel drug-enhancing strategy  ScienceDirect.com

Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new fro...

Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new frontier in chemotherapeutic efficacy and cancer therapy  Nature

Neuronal protective effect of Artemisinin in ischemic stroke: Achieved by blocking lysine demethy...

Neuronal protective effect of Artemisinin in ischemic stroke: Achieved by blocking lysine demethylase 1A-mediated demethylation of sphingosine kinase 2  ScienceDirect.com

Therapeutic applications of artemisinin in ophthalmic diseases - ScienceDirect.com

Therapeutic applications of artemisinin in ophthalmic diseases  ScienceDirect.com

Oral glucose-responsive nanoparticles loaded with artemisinin induce pancreatic β-cell regenerati...

Oral glucose-responsive nanoparticles loaded with artemisinin induce pancreatic β-cell regeneration for the treatment of type 2 diabetes  ScienceDirect.com

Design, synthesis, and biological evaluation of novel artemisinin-based HDAC inhibitors with anti...

Design, synthesis, and biological evaluation of novel artemisinin-based HDAC inhibitors with antitumor and antimalarial activities  ScienceDirect.com

Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding ...

Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding affinity and decreased artemisinin activation | Communications Biology  Nature

Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Pla...

Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Plasmodium berghei -infected mice  Parasites & Vectors

Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance ...

Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance in Plasmodium berghei K173 based on targeted metabolomics  Nature

Emerging trends and new developments in global research on artemisinin and its derivatives - Scie...

Emerging trends and new developments in global research on artemisinin and its derivatives  ScienceDirect.com

Artemisinin production strategies for industrial scale: Current progress and future directions - ...

Artemisinin production strategies for industrial scale: Current progress and future directions  ScienceDirect.com

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover ...

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background  Nature

Artemisinin-resistant malaria - ASM Journals

Artemisinin-resistant malaria  ASM Journals

Impact of the Global Fund Regional Artemisinin-resistance Initiative on malaria control and elimi...

Impact of the Global Fund Regional Artemisinin-resistance Initiative on malaria control and elimination in the Greater Mekong subregion of southeast Asia  The Lancet

Plant growth-promoting endophytic consortium improved artemisinin biosynthesis via modulating ant...

Plant growth-promoting endophytic consortium improved artemisinin biosynthesis via modulating antioxidants, gene expression, and transcriptional profile in Artemisia annua (L.) under stressed environments  ScienceDirect.com

Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mu...

Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mutation detection in Asia  Nature

In-silico identification of sulfur and selenium analogous to artemisinin as potential antimalaria...

In-silico identification of sulfur and selenium analogous to artemisinin as potential antimalarial drug candidates  ScienceDirect.com

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylprop...

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua  Nature

Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast...

Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure  Nature

Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1 - Nature

Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1  Nature

Artemisinin and absinthin production in response to exogenous methyl jasmonate and chilling in Ar...

Artemisinin and absinthin production in response to exogenous methyl jasmonate and chilling in Artemisia absinthium L. in vitro propagated plantlets  ScienceDirect.com

Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in...

Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in Plasmodium falciparum  ASM Journals

Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations l...

Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations linked to delayed clearance after artemisinin-lumefantrine treatment  Nature

Increased artemisinin production in Artemisia annua L. by co-overexpression of six key biosynthet...

Increased artemisinin production in Artemisia annua L. by co-overexpression of six key biosynthetic enzymes  ScienceDirect.com

Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal ...

Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal disorders, autoimmune inflammatory diseases, and autoimmune disorders: a comprehensive review  Frontiers

The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular qui...

The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular quiescence/senescence and drug resilience  Nature

The spread of molecular markers of artemisinin partial resistance and diagnostic evasion in Eritr...

The spread of molecular markers of artemisinin partial resistance and diagnostic evasion in Eritrea: a retrospective molecular epidemiology study  The Lancet

Experimental and model-based approach to evaluate solvent effects on the solubility of the pharma...

Experimental and model-based approach to evaluate solvent effects on the solubility of the pharmaceutical artemisinin  ScienceDirect.com

Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy ...

Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy in the Kenyan Central highlands: a zone previously characterized as malaria-free  Malaria Journal

Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hy...

Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development  Nature

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea - New England Jou...

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea  New England Journal of Medicine

Artemisinin and its derivatives modulate glucose homeostasis and gut microbiota remodeling in a n...

Artemisinin and its derivatives modulate glucose homeostasis and gut microbiota remodeling in a nutritional context  ScienceDirect.com

New clinical application prospects of artemisinin and its derivatives: a scoping review - Infecti...

New clinical application prospects of artemisinin and its derivatives: a scoping review  Infectious Diseases of Poverty

Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics - ScienceDirect.com

Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics  ScienceDirect.com

Evidence of Artemisinin-Resistant Malaria in Africa - New England Journal of Medicine

Evidence of Artemisinin-Resistant Malaria in Africa  New England Journal of Medicine

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R5...

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda  Nature

Artemisinin-resistant malaria in Africa demands urgent action - Science | AAAS

Artemisinin-resistant malaria in Africa demands urgent action  Science | AAAS

Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation - Frontiers

Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation  Frontiers

Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate ox...

Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate oxidative stress  Frontiers

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to ...

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin  PNAS

Expression of key genes affecting artemisinin content in five Artemisia species - Nature

Expression of key genes affecting artemisinin content in five Artemisia species  Nature

Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum - ASM Journals

Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum  ASM Journals

Therapeutic potential of artemisinin and its derivatives in managing kidney diseases - Frontiers

Therapeutic potential of artemisinin and its derivatives in managing kidney diseases  Frontiers

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodi...

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum  Nature

Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria para...

Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa  Nature

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite - Nature

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite  Nature

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1...

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway  ScienceDirect.com

Nutrient Limitation Mimics Artemisinin Tolerance in Malaria - ASM Journals

Nutrient Limitation Mimics Artemisinin Tolerance in Malaria  ASM Journals

Artemisinin and deoxyartemisinin isolated from Artemisia annua L. promote distinct antinociceptiv...

Artemisinin and deoxyartemisinin isolated from Artemisia annua L. promote distinct antinociceptive and anti-inflammatory effects in an animal model  ScienceDirect.com

Modeling policy interventions for slowing the spread of artemisinin-resistant pfkelch R561H mutat...

Modeling policy interventions for slowing the spread of artemisinin-resistant pfkelch R561H mutations in Rwanda  Nature

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initia...

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response  Nature

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum - Nature

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum  Nature

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa - New England Journ...

Emergence of Indigenous Artemisinin-Resistant Plasmodium falciparum in Africa  New England Journal of Medicine

Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemi...

Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance  ScienceDirect.com

Artemisinin derivatives induce oxidative stress leading to DNA damage and caspase-mediated apopto...

Artemisinin derivatives induce oxidative stress leading to DNA damage and caspase-mediated apoptosis in Theileria annulata-transformed cells  Cell Communication and Signaling

Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted ...

Artemisinin Mediates Its Tumor-Suppressive Activity in Hepatocellular Carcinoma Through Targeted Inhibition of FoxM1  Frontiers

Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases - S...

Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases  ScienceDirect.com

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome - Nature

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome  Nature

Artemisinin anti-malarial drugs in China - ScienceDirect.com

Artemisinin anti-malarial drugs in China  ScienceDirect.com

Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a sys...

Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a systematic review and spatiotemporal analysis  The Lancet

Still time to contain artemisinin resistance in Africa - The Lancet

Still time to contain artemisinin resistance in Africa  The Lancet

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resist...

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance  Science | AAAS

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites - Scie...

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites  Science | AAAS

The SPB-Box Transcription Factor AaSPL2 Positively Regulates Artemisinin Biosynthesis in Artemisi...

The SPB-Box Transcription Factor AaSPL2 Positively Regulates Artemisinin Biosynthesis in Artemisia annua L.  Frontiers

Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa - New England Journal of Medicine

Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa  New England Journal of Medicine

Facilitated Drug Repurposing with Artemisinin-Derived PROTACs: Unveiling PCLAF as a Therapeutic T...

Facilitated Drug Repurposing with Artemisinin-Derived PROTACs: Unveiling PCLAF as a Therapeutic Target  ACS Publications

Africa's race against time to stop malaria drug resistance - Gavi, the Vaccine Alliance

Africa's race against time to stop malaria drug resistance  Gavi, the Vaccine Alliance

Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds - Na...

Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds  Nature

Jasmonate promotes artemisinin biosynthesis by activating the TCP14-ORA complex in Artemisia annu...

Jasmonate promotes artemisinin biosynthesis by activating the TCP14-ORA complex in Artemisia annua  Science | AAAS

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near co...

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania  Nature

Access to Artemisinin–Triazole Antimalarials via Organo-Click Reaction: High In Vitro In Vivo Act...

Access to Artemisinin–Triazole Antimalarials via Organo-Click Reaction: High In Vitro In Vivo Activity against Multi-Drug-Resistant Malaria Parasites  ACS Publications

Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeuti...

Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms  Nature

Photoaffinity probe-based antimalarial target identification of artemisinin in the intraerythrocy...

Photoaffinity probe-based antimalarial target identification of artemisinin in the intraerythrocytic developmental cycle of Plasmodium falciparum  Wiley Online Library

Artemisia annua mutant impaired in artemisinin synthesis demonstrates importance of nonenzymatic ...

Artemisia annua mutant impaired in artemisinin synthesis demonstrates importance of nonenzymatic conversion in terpenoid metabolism  PNAS

Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release | ...

Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release | Scientific Reports  Nature

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic p...

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic program to enhance survival  Nature

Enhancing activity of β-lactam and fluoroquinolones antibiotics by artemisinin and its derivative...

Enhancing activity of β-lactam and fluoroquinolones antibiotics by artemisinin and its derivatives against MDR Escherichia coli  Frontiers

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria - New England Journal of Medicine

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria  New England Journal of Medicine

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia - Nature

Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia  Nature

DNA binding by the antimalarial compound artemisinin - Nature

DNA binding by the antimalarial compound artemisinin  Nature

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis - Nature

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis  Nature

Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB...

Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB-1 signaling pathway  Nature

Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis - ...

Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis  Frontiers

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria - Nature

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria  Nature

Inhibiting the Plasmodium eIF2α Kinase PK4 Prevents Artemisinin-Induced Latency - ScienceDirect.com

Inhibiting the Plasmodium eIF2α Kinase PK4 Prevents Artemisinin-Induced Latency  ScienceDirect.com

Novel use for old drugs: The emerging role of artemisinin and its derivatives in fibrosis - Scien...

Novel use for old drugs: The emerging role of artemisinin and its derivatives in fibrosis  ScienceDirect.com