"アルテミシニン" の関連情報検索結果

Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis - N...



Dihydroartemisinic acid dehydrogenase-mediated alternative route for artemisinin biosynthesis  Nature

Discovery of D-Ring-Contracted Artemisinin as a Potent Hydrophobic Tag for Targeted Protein Degra...



Discovery of D-Ring-Contracted Artemisinin as a Potent Hydrophobic Tag for Targeted Protein Degradation  ACS Publications

Artemisinin-resistant malaria - ASM Journals



Artemisinin-resistant malaria  ASM Journals

Artemisinin-resistant malaria in Africa demands urgent action - Science | AAAS



Artemisinin-resistant malaria in Africa demands urgent action  Science | AAAS

Artemisinin alleviates cisplatin-induced damage in GC-1 spermatogonia through ER stress mechanism...



Artemisinin alleviates cisplatin-induced damage in GC-1 spermatogonia through ER stress mechanisms  ScienceDirect.com

Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance ...



Spatial regulation of chrysosplenetin on amino acid homeostasis linked to artemisinin resistance in Plasmodium berghei K173 based on targeted metabolomics  Nature

Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor ...



Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid  ACS Publications

Artemisinin-resistant malaria | Clinical Microbiology Reviews - ASM Journals



Artemisinin-resistant malaria | Clinical Microbiology Reviews  ASM Journals

Emerging trends and new developments in global research on artemisinin and its derivatives - Scie...



Emerging trends and new developments in global research on artemisinin and its derivatives  ScienceDirect.com

Mechanistic Insights into the Nonenzymatic Biosynthesis of Artemisinin and Related Natural Produc...



Mechanistic Insights into the Nonenzymatic Biosynthesis of Artemisinin and Related Natural Products: A Quantum Chemical Study  ACS Publications

Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding ...



Artemisinin-resistant Plasmodium falciparum Kelch13 mutant proteins display reduced heme-binding affinity and decreased artemisinin activation | Communications Biology  Nature

Therapeutic applications of artemisinin in ophthalmic diseases - ScienceDirect.com



Therapeutic applications of artemisinin in ophthalmic diseases  ScienceDirect.com

Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1 - Nature



Artemisinin inhibits neuronal ferroptosis in Alzheimer’s disease models by targeting KEAP1  Nature

Thymoquinone, artemisinin, and thymol attenuate proliferation of lung cancer cells as Sphingosine...



Thymoquinone, artemisinin, and thymol attenuate proliferation of lung cancer cells as Sphingosine kinase 1 inhibitors  ScienceDirect.com

The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression ...



The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment  Nature

The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular qui...



The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular quiescence/senescence and drug resilience  Nature

Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new fro...



Efficient PEGylated magnetic nanoniosomes for co-delivery of artemisinin and metformin: a new frontier in chemotherapeutic efficacy and cancer therapy  Nature

Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mu...



Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mutation detection in Asia  Nature

Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast...



Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure  Nature

Artemisinin and deoxyartemisinin isolated from Artemisia annua L. promote distinct antinociceptiv...



Artemisinin and deoxyartemisinin isolated from Artemisia annua L. promote distinct antinociceptive and anti-inflammatory effects in an animal model  ScienceDirect.com

Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Pla...



Taurine potentiates artemisinin efficacy against malaria by modulating the immune response in Plasmodium berghei -infected mice  Parasites & Vectors

Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover ...



Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background  Nature

Resistance to crucial malaria drug detected in severely ill kids in Africa - Nature



Resistance to crucial malaria drug detected in severely ill kids in Africa  Nature

Impact of the Global Fund Regional Artemisinin-resistance Initiative on malaria control and elimi...



Impact of the Global Fund Regional Artemisinin-resistance Initiative on malaria control and elimination in the Greater Mekong subregion of southeast Asia  The Lancet

Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in...



Enhanced cell stress response and protein degradation capacity underlie artemisinin resistance in Plasmodium falciparum  ASM Journals

Artemisinin modulates integrin‐mediated focal adhesion kinase (FAK)... - ResearchGate



Artemisinin modulates integrin‐mediated focal adhesion kinase (FAK)...  ResearchGate

What's going on with the 'magic' drug for malaria? - NPR



What's going on with the 'magic' drug for malaria?  NPR

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylprop...



Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua  Nature

Increased artemisinin production in Artemisia annua L. by co-overexpression of six key biosynthet...



Increased artemisinin production in Artemisia annua L. by co-overexpression of six key biosynthetic enzymes  ScienceDirect.com

Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodar...



Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway  Journal of Translational Medicine

Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine–pyrimetham...



Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine–pyrimethamine resistance in 13 regions in Tanzania in 2021: a cross-sectional survey  The Lancet

Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations l...



Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations linked to delayed clearance after artemisinin-lumefantrine treatment  Nature

Partial resistance to key malaria drug found in young children in Uganda - CIDRAP



Partial resistance to key malaria drug found in young children in Uganda  CIDRAP

Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal ...



Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal disorders, autoimmune inflammatory diseases, and autoimmune disorders: a comprehensive review  Frontiers

Regional stakeholder meeting on the response to antimalarial drug resistance in Africa - World He...



Regional stakeholder meeting on the response to antimalarial drug resistance in Africa  World Health Organization (WHO)

Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate ox...



Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate oxidative stress  Frontiers

Still time to contain artemisinin resistance in Africa - The Lancet Microbe - The Lancet



Still time to contain artemisinin resistance in Africa - The Lancet Microbe  The Lancet

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1...



Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway  ScienceDirect.com

Emoquine-1: A Hybrid Molecule Efficient against Multidrug-Resistant Plasmodium Parasites, Includi...



Emoquine-1: A Hybrid Molecule Efficient against Multidrug-Resistant Plasmodium Parasites, Including the Artemisinin-Resistant Quiescent Stage, and Also Active In Vivo  ACS Publications

Artemisinin resistance detected in children with severe malaria in Uganda - News-Medical



Artemisinin resistance detected in children with severe malaria in Uganda  News-Medical

The spread of molecular markers of artemisinin partial resistance and diagnostic evasion in Eritr...



The spread of molecular markers of artemisinin partial resistance and diagnostic evasion in Eritrea: a retrospective molecular epidemiology study  The Lancet

Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular marke...



Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular markers of resistance  The Lancet

Herb-induced hepatitis secondary to artemisinin: A case report - Frontiers



Herb-induced hepatitis secondary to artemisinin: A case report  Frontiers

Polycystic Ovaries: An anti-malaria compound, a possible treatment for the syndrome - Hospital Cl...



Polycystic Ovaries: An anti-malaria compound, a possible treatment for the syndrome  Hospital Clínic Barcelona

Artemisitene shows superiority over artemisinin in preventing Schistosoma japonica-induced liver ...



Artemisitene shows superiority over artemisinin in preventing Schistosoma japonica-induced liver disease  Parasites & Vectors

Fears for spread of malaria in Africa as study finds resistance to frontline drug - The Guardian



Fears for spread of malaria in Africa as study finds resistance to frontline drug  The Guardian

Neuroprotective effects and mechanisms of action of artemisinin in retinal ganglion cells in a mo...



Neuroprotective effects and mechanisms of action of artemisinin in retinal ganglion cells in a mouse model of traumatic optic neuropathy  ScienceDirect.com

Alarming Plasmodium falciparum resistance to artemisinin-based combination therapy in Africa: the...



Alarming Plasmodium falciparum resistance to artemisinin-based combination therapy in Africa: the critical role of the partner drug  The Lancet

Enhancing activity of β-lactam and fluoroquinolones antibiotics by artemisinin and its derivative...



Enhancing activity of β-lactam and fluoroquinolones antibiotics by artemisinin and its derivatives against MDR Escherichia coli  Frontiers

'No evidence' anti-malaria drug artemisinin prevents or treats mpox: scientists - AFP Fact Check



'No evidence' anti-malaria drug artemisinin prevents or treats mpox: scientists  AFP Fact Check

Artemisinin Antimalarial Drugs Market Size & Share Report - 2032 - Global Market Insights Inc.



Artemisinin Antimalarial Drugs Market Size & Share Report - 2032  Global Market Insights Inc.

(PDF) Extraction of Artemisinin, an Active Antimalarial Phytopharmaceutical from Dried Leaves of ...



(PDF) Extraction of Artemisinin, an Active Antimalarial Phytopharmaceutical from Dried Leaves of Artemisia annua L., Using Microwaves and a Validated HPTLC-Visible Method for Its Quantitative Determination  ResearchGate

(PDF) Artemisinin-loaded mesoporous silica nanoparticles/electrospun poly(lactic-co-glycolic acid...



(PDF) Artemisinin-loaded mesoporous silica nanoparticles/electrospun poly(lactic-co-glycolic acid) composite nanofibers for enhanced anticancer efficiency in breast cancer cells  ResearchGate

The emergence of artemisinin partial resistance in Africa: how do we respond? - The Lancet Infect...



The emergence of artemisinin partial resistance in Africa: how do we respond? - The Lancet Infectious Diseases  The Lancet

Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy ...



Malaria prevalence, transmission potential and efficacy of artemisinin-based combination therapy in the Kenyan Central highlands: a zone previously characterized as malaria-free  Malaria Journal

Urgent action needed as malaria evolves resistance to key drug - BBC



Urgent action needed as malaria evolves resistance to key drug  BBC

Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3...



Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in Plasmodium falciparum infections from Rukara, Rwanda  Malaria Journal

(PDF) Using supply side evidence to inform oral artemisinin monotherapy replacement in Myanmar: A...



(PDF) Using supply side evidence to inform oral artemisinin monotherapy replacement in Myanmar: A case study  ResearchGate

(PDF) Evaluation of the Quality of Artemisinin-Based Antimalarial Medicines Distributed in Ghana ...



(PDF) Evaluation of the Quality of Artemisinin-Based Antimalarial Medicines Distributed in Ghana and Togo  ResearchGate

Figure 2. The antimalarial mechanism of artemisinin. Heme and iron... - ResearchGate



Figure 2. The antimalarial mechanism of artemisinin. Heme and iron...  ResearchGate

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea - The New England...



Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea  The New England Journal of Medicine

Mutations in PfCoronin conferring resistance to artemisinin are at... - ResearchGate



Mutations in PfCoronin conferring resistance to artemisinin are at...  ResearchGate

(PDF) Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with...



(PDF) Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-analysis of individual patient data  ResearchGate

Figure 4. Spread of artemisinin resistance frequency in Africa. The... - ResearchGate



Figure 4. Spread of artemisinin resistance frequency in Africa. The...  ResearchGate

The P. falciparum artemisinin resistance determinant K13 localizes to... - ResearchGate



The P. falciparum artemisinin resistance determinant K13 localizes to...  ResearchGate

Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hy...



Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development  Nature

Artemisinin mechanism of action against malaria parasite; (i)... - ResearchGate



Artemisinin mechanism of action against malaria parasite; (i)...  ResearchGate

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R5...



Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda  Nature

Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa - The New England Journal of M...



Artemisinin-Resistant and HRP-Negative Malaria Parasites in Africa  The New England Journal of Medicine

The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite - Nature



The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite  Nature

Aging affects artemisinin synthesis in Artemisia annua - Nature



Aging affects artemisinin synthesis in Artemisia annua  Nature

Schematic view of Artemisinin biosynthesis pathway. MVA, mevalonate... - ResearchGate



Schematic view of Artemisinin biosynthesis pathway. MVA, mevalonate...  ResearchGate

Evidence of Artemisinin-Resistant Malaria in Africa - The New England Journal of Medicine



Evidence of Artemisinin-Resistant Malaria in Africa  The New England Journal of Medicine

(PDF) Acquired resistance of malarial parasites against artemisinin-based drugs: social and econo...



(PDF) Acquired resistance of malarial parasites against artemisinin-based drugs: social and economic impacts  ResearchGate

Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum - ASM Journals



Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum  ASM Journals

Gram‐scale of synthesis and derivatization of artemisinin G. - ResearchGate



Gram‐scale of synthesis and derivatization of artemisinin G.  ResearchGate

New clinical application prospects of artemisinin and its derivatives: a scoping review - BioMed ...



New clinical application prospects of artemisinin and its derivatives: a scoping review  BioMed Central

Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodi...



Protein KIC5 is a novel regulator of artemisinin stress response in the malaria parasite Plasmodium falciparum  Nature

Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome - Nature



Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome  Nature

Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds - Na...



Bioprospecting of Artemisia genus: from artemisinin to other potentially bioactive compounds  Nature

The signaling mechanisms underlying effects of artemisinin and its... - ResearchGate



The signaling mechanisms underlying effects of artemisinin and its...  ResearchGate

Nutrient Limitation Mimics Artemisinin Tolerance in Malaria - ASM Journals



Nutrient Limitation Mimics Artemisinin Tolerance in Malaria  ASM Journals

Artemisinin and clinical derivatives DHA, artemether and artesunate.... - ResearchGate



Artemisinin and clinical derivatives DHA, artemether and artesunate....  ResearchGate

Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near co...



Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania  Nature

A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites - Scie...



A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites  Science | AAAS

Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis | Cell...



Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis | Cell Death & Differentiation  Nature

Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemi...



Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance  ScienceDirect.com

Artemisia annua mutant impaired in artemisinin synthesis demonstrates importance of nonenzymatic ...



Artemisia annua mutant impaired in artemisinin synthesis demonstrates importance of nonenzymatic conversion in terpenoid metabolism  PNAS

(PDF) Ascorbic acid co-administration with artemisinin based combination therapies in falciparum ...



(PDF) Ascorbic acid co-administration with artemisinin based combination therapies in falciparum malaria  ResearchGate

Therapeutic effects of artemisinin and its derivatives. Artemisinin... - ResearchGate



Therapeutic effects of artemisinin and its derivatives. Artemisinin...  ResearchGate

Applying green chemistry to the photochemical route to artemisinin - Nature



Applying green chemistry to the photochemical route to artemisinin  Nature

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic p...



Artemisinin-resistant K13 mutations rewire Plasmodium falciparum s intra-erythrocytic metabolic program to enhance survival  Nature

Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a sys...



Mapping genetic markers of artemisinin resistance in Plasmodium falciparum malaria in Asia: a systematic review and spatiotemporal analysis - The Lancet Microbe  The Lancet

Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeuti...



Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms  Nature

Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum - Nature



Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum  Nature

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initia...



Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response  Nature

Expression of key genes affecting artemisinin content in five Artemisia species - Nature



Expression of key genes affecting artemisinin content in five Artemisia species  Nature

Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 an...



Efficacy and safety of artemisinin-based combination therapy and the implications of Pfkelch13 and Pfcoronin molecular markers in treatment failure in Senegal  Nature

Researchers evaluate artemisinin for COVID-19 management - News-Medical



Researchers evaluate artemisinin for COVID-19 management  News-Medical

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria - Nature



A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria  Nature