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Neuronal AcCoA Signaling Linked to Autophagy Defects in Alzheimer’s - Neuroscience News



Neuronal AcCoA Signaling Linked to Autophagy Defects in Alzheimer’s  Neuroscience News

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature



A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS



ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...



A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

The ribosome-associated N-terminal acetyltransferase B coordinates global proteostasis and autoph...



The ribosome-associated N-terminal acetyltransferase B coordinates global proteostasis and autophagy in plants by creating Ac/N-degrons  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature



Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...



Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...



Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

The Japan autophagy consortium - Nature



The Japan autophagy consortium  Nature

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...



Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Small-molecule inhibitor of C‑terminal HSP90 dimerization modulates autophagy and functions syner...



Small-molecule inhibitor of C‑terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells | Cell Death & Disease  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticle...



Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Phagoflux: From Research to Cutting-Edge Autophagy Solutions - Stellenbosch University



Phagoflux: From Research to Cutting-Edge Autophagy Solutions  Stellenbosch University

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B - Rockefeller ...



The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B  Rockefeller University Press

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...



Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...



Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Autophagy: Regulator of cell death - Nature



Autophagy: Regulator of cell death  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...



HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Disulfiram Reduces Atherosclerosis and Enhances Efferocytosis, Autophagy, and Atheroprotective Gu...



Disulfiram Reduces Atherosclerosis and Enhances Efferocytosis, Autophagy, and Atheroprotective Gut Microbiota in Hyperlipidemic Mice  American Heart Association Journals

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App kno...



Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai



Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals



Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS



Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature



Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com



Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...



TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...



Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature



Autophagy promotes jasmonate-mediated defense against nematodes  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence -...



Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Impact of context-dependent autophagy states on tumor progression - Nature



Impact of context-dependent autophagy states on tumor progression  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing - Nature



Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing  Nature

TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DN...



TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA  Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature