A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Lisinopril activates BI1 to reprogram lipid metabolism and restore autophagy in ALS - Nature

Lisinopril activates BI1 to reprogram lipid metabolism and restore autophagy in ALS  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS

ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - rupress.org

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  rupress.org

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Platelet-rich plasma promotes cellular recovery from nicotine-induced toxicity via autophagy modu...

Platelet-rich plasma promotes cellular recovery from nicotine-induced toxicity via autophagy modulation  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidatio...

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidation  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

Autophagy Defects in SNCA Triplication Neurons - Bioengineer.org

Autophagy Defects in SNCA Triplication Neurons  Bioengineer.org

Regulation of autophagy and its role in late preimplantation during mouse embryo development - Na...

Regulation of autophagy and its role in late preimplantation during mouse embryo development  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - rupress.org

The rapidly expanding role of LC3-interacting regions in autophagy  rupress.org

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - rupre...

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  rupress.org

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries - Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Rab GTPases as “eat me” signals for selective autophagy - rupress.org

Rab GTPases as “eat me” signals for selective autophagy  rupress.org

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac ...

SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac hypertrophy  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses | Scientific Reports  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Next questions in autophagy - Nature

Next questions in autophagy  Nature

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai

Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - NEJM

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  NEJM

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Self-Eating Decisions - hms.harvard.edu

Self-Eating Decisions  hms.harvard.edu

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences

Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease - Frontiers

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease  Frontiers

Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer...

Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer cells  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

On the caveats of AI autophagy - Nature

On the caveats of AI autophagy  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature

Redefining the role of AMPK in autophagy and the energy stress response  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS

Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Altered extracellular mRNA communication in postpartum depression is associated with decreased au...

Altered extracellular mRNA communication in postpartum depression is associated with decreased autophagy  Nature

Autophagy in tumour immunity and therapy - Nature

Autophagy in tumour immunity and therapy  Nature

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can...

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from?  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com

Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Defective autophagy leads to cancer - ScienceDirect.com

Defective autophagy leads to cancer  ScienceDirect.com

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human gen...

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics  PNAS

SARS-CoV-2 promote autophagy to suppress type I interferon response - Nature

SARS-CoV-2 promote autophagy to suppress type I interferon response  Nature