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TRIM21 marks viruses and bacteria for degradation via autophagy - BioWorld News



TRIM21 marks viruses and bacteria for degradation via autophagy  BioWorld News

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers



Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...



A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Bacteriocin-transport–inspired oral peptide-probiotic delivery ameliorates IBD complications via ...



Bacteriocin-transport–inspired oral peptide-probiotic delivery ameliorates IBD complications via autophagy and gut homeostasis  Science | AAAS

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...



A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...



Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...



SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

ULK1 knockout suppresses pancreatic cancer progression by inhibiting autophagy and enhancing anti...



ULK1 knockout suppresses pancreatic cancer progression by inhibiting autophagy and enhancing antitumor immunity  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature



A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...



Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Ballabio Awarded the Beth Levine, M.D. Prize in Autophagy Research - Texas Children’s



Ballabio Awarded the Beth Levine, M.D. Prize in Autophagy Research  Texas Children’s

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Phagoflux: From Research to Cutting-Edge Autophagy Solutions - Stellenbosch University



Phagoflux: From Research to Cutting-Edge Autophagy Solutions  Stellenbosch University

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

Impact of context-dependent autophagy states on tumor progression - Nature



Impact of context-dependent autophagy states on tumor progression  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhanceme...



Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS



Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy and microbial pathogenesis - Cell Death & Differentiation - Nature



Autophagy and microbial pathogenesis - Cell Death & Differentiation  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...



TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...



Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature



Autophagy promotes jasmonate-mediated defense against nematodes  Nature

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing - Nature



Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com



Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai



Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - NEJM



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  NEJM

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature



Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

Autophagy as a promoter of longevity: insights from model organisms - Nature



Autophagy as a promoter of longevity: insights from model organisms  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals



Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Autophagy regulation by RNA alternative splicing and implications in human diseases - Nature



Autophagy regulation by RNA alternative splicing and implications in human diseases  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature



A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals ...



SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS



Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ...



TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress  Nature

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-dri...



Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature



Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis - American Heart Association Journals



microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis  American Heart Association Journals

Cellular quality control by the ubiquitin-proteasome system and autophagy - Science | AAAS



Cellular quality control by the ubiquitin-proteasome system and autophagy  Science | AAAS

Staged suppression of microglial autophagy facilitates regeneration in CNS demyelination by enhan...



Staged suppression of microglial autophagy facilitates regeneration in CNS demyelination by enhancing the production of linoleic acid  PNAS

A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the...



A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery  Nature