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Targeting LAPTM5 enhances AML sensitivity to cytarabine through autophagy inhibition - Nature



Targeting LAPTM5 enhances AML sensitivity to cytarabine through autophagy inhibition  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS



ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...



Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...



The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with a...



Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...



Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

The Japan autophagy consortium - Nature



The Japan autophagy consortium  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature



Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...



Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Crosstalk between acetylation modification and autophagy in cancer: roles, mechanisms, and therap...



Crosstalk between acetylation modification and autophagy in cancer: roles, mechanisms, and therapeutic potential  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...



Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidatio...



AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidation  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...



Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...



SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in genta...



Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...



Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature



Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy as a potential therapeutic target in regulating improper cellular proliferation - Front...



Autophagy as a potential therapeutic target in regulating improper cellular proliferation  Frontiers

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention - Front...



Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention  Frontiers

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...



PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST...



Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)  PNAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scienti...



Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scientific Reports  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...



LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses | Scientific Reports  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Autophagy: Regulator of cell death - Nature



Autophagy: Regulator of cell death  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - NEJM



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  NEJM

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences



Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease - Frontiers



Editorial: Autophagy: unveiling the mechanisms and implications in health and disease  Frontiers

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes - Rockefeller U...



TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes  Rockefeller University Press

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Self-Eating Decisions - Harvard Medical School



Self-Eating Decisions  Harvard Medical School

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS



Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Autophagy in tumour immunity and therapy - Nature



Autophagy in tumour immunity and therapy  Nature

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can...



Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from?  Nature

Next questions in autophagy - Nature



Next questions in autophagy  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com



Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy - Nature



Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy  Nature

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human gen...



Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics  PNAS

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature



The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition...



Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells | Cell Death & Disease  Nature