K48 and K63 linkage-competed ubiquitination of BECN1 promotes circPDE4D-mediated autophagy in chr...

K48 and K63 linkage-competed ubiquitination of BECN1 promotes circPDE4D-mediated autophagy in chronic obstructive pulmonary disease  Nature

Anavex Life Sciences Announces New Study Linking Autophagy Dysfunction to Alzheimer’s Disease Pat...

Anavex Life Sciences Announces New Study Linking Autophagy Dysfunction to Alzheimer’s Disease Pathology  Quiver Quantitative

New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta ...

New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease  The Manila Times

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche o...

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β...

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press

Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy Is Required for Strawberry Fruit Ripening - Frontiers

Autophagy Is Required for Strawberry Fruit Ripening  Frontiers

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

Autophagy in tumour immunity and therapy - Nature

Autophagy in tumour immunity and therapy  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and r...

Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scienti...

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scientific Reports  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

The emerging roles of circular RNA-mediated autophagy in tumorigenesis and cancer progression - N...

The emerging roles of circular RNA-mediated autophagy in tumorigenesis and cancer progression  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34...

The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

The role of autophagy in prostate cancer and prostatic diseases: a new therapeutic strategy - Nature

The role of autophagy in prostate cancer and prostatic diseases: a new therapeutic strategy  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Next questions in autophagy - Nature

Next questions in autophagy  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature

Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during...

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging  Nature

Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppressi...

Metformin inhibits the growth of SCLC cells by inducing autophagy and apoptosis via the suppression of EGFR and AKT signalling  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses - Nature

TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses  Nature

Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance - Nature

Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

ATPase activity of DFCP1 controls selective autophagy - Nature

ATPase activity of DFCP1 controls selective autophagy  Nature

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences

Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

On the caveats of AI autophagy - Nature

On the caveats of AI autophagy  Nature