Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS

ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

Autophagy angle sharpens Anavex’s investment case for Alzheimer’s - longevity.technology

Autophagy angle sharpens Anavex’s investment case for Alzheimer’s  longevity.technology

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidatio...

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidation  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

Editorial: Interactions between autophagy and immune response: cell communication and disease imp...

Editorial: Interactions between autophagy and immune response: cell communication and disease implications  Frontiers

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy as a potential therapeutic target in regulating improper cellular proliferation - Front...

Autophagy as a potential therapeutic target in regulating improper cellular proliferation  Frontiers

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy - PNAS

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy  PNAS

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST...

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)  PNAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy - Nature

Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature

Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature

Redefining the role of AMPK in autophagy and the energy stress response  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Autophagy: Definition, Diet, Fasting, Cancer, Benefits, and More - Healthline

Autophagy: Definition, Diet, Fasting, Cancer, Benefits, and More  Healthline

Autophagy in tumour immunity and therapy - Nature

Autophagy in tumour immunity and therapy  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cell...

Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells  Nature

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature

Next questions in autophagy - Nature

Next questions in autophagy  Nature

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence -...

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence  Nature

TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes - Rockefeller U...

TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes  Rockefeller University Press

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human gen...

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics  PNAS

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature

Autophagy promotes jasmonate-mediated defense against nematodes  Nature

The mTOR–Autophagy Axis and the Control of Metabolism - Frontiers

The mTOR–Autophagy Axis and the Control of Metabolism  Frontiers

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy - Nature

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy  Nature

Autophagy and autophagy-related pathways in cancer - Nature

Autophagy and autophagy-related pathways in cancer  Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature