Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy - Rockefeller Univer...

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy  Rockefeller University Press

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS

ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

Autophagy: the cell’s waste disposal system | AutoClean Project | Results in Brief | H2020 - CORDIS

Autophagy: the cell’s waste disposal system | AutoClean Project | Results in Brief | H2020  CORDIS

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature

Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development - Frontiers

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development  Frontiers

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Ballabio Awarded the Beth Levine, M.D. Prize in Autophagy Research - Texas Children’s

Ballabio Awarded the Beth Levine, M.D. Prize in Autophagy Research  Texas Children’s

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B - Rockefeller ...

The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B  Rockefeller University Press

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Phagoflux: From Research to Cutting-Edge Autophagy Solutions - Stellenbosch University

Phagoflux: From Research to Cutting-Edge Autophagy Solutions  Stellenbosch University

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Autophagy and Erectile Dysfunction: What the Cellular Cleanup Process Might Mean for Men's Health...

Autophagy and Erectile Dysfunction: What the Cellular Cleanup Process Might Mean for Men's Health  Portal CNJ

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

Impact of context-dependent autophagy states on tumor progression - Nature

Impact of context-dependent autophagy states on tumor progression  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhanceme...

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals

Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension...

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension  American Heart Association Journals

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS

Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

On the caveats of AI autophagy - Nature

On the caveats of AI autophagy  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai

Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com

Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS

Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press

Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Autophagy as a promoter of longevity: insights from model organisms - Nature

Autophagy as a promoter of longevity: insights from model organisms  Nature

ATPase activity of DFCP1 controls selective autophagy - Nature

ATPase activity of DFCP1 controls selective autophagy  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature

Redefining the role of AMPK in autophagy and the energy stress response  Nature

PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in...

PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice  American Heart Association Journals

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Autophagy in Atherosclerosis: Not All Foam Cells Are Created Equal - American Heart Association J...

Autophagy in Atherosclerosis: Not All Foam Cells Are Created Equal  American Heart Association Journals

Autophagy regulation by RNA alternative splicing and implications in human diseases - Nature

Autophagy regulation by RNA alternative splicing and implications in human diseases  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Defective autophagy leads to cancer - ScienceDirect.com

Defective autophagy leads to cancer  ScienceDirect.com

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depress...

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature

Autophagy promotes jasmonate-mediated defense against nematodes  Nature

Targeting Chaperone-Mediated Autophagy in Cancer - Science | AAAS

Targeting Chaperone-Mediated Autophagy in Cancer  Science | AAAS

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ...

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress  Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature