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Targeting mitochondrial autophagy for anti-aging - Nature



Targeting mitochondrial autophagy for anti-aging  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Autophagy across tissues of aging mice - PLOS



Autophagy across tissues of aging mice  PLOS

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with a...



Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...



Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...



Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche o...



DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma  Nature

Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression - Na...



Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression  Nature

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticle...



Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature



Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β...



Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature



Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...



Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...



Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries - Nature



Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature



PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology - Nature



Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during...



Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treatin...



AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields) | Cell Death & Disease  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...



PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Autophagy: Regulator of cell death - Cell Death & Disease - Nature



Autophagy: Regulator of cell death - Cell Death & Disease  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers



Interplay Between NLRP3 Inflammasome and Autophagy  Frontiers

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms throug...



BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking | Communications Biology  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

The Hedgehog signalling pathway regulates autophagy - Nature



The Hedgehog signalling pathway regulates autophagy  Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature



Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature



A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

ATPase activity of DFCP1 controls selective autophagy - Nature



ATPase activity of DFCP1 controls selective autophagy  Nature

Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps - Frontiers



Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps  Frontiers

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary f...



Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease  PNAS

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia - Nature



Autophagy of mucin granules contributes to resolution of airway mucous metaplasia  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Autophagy in Human Diseases - The New England Journal of Medicine



Autophagy in Human Diseases  The New England Journal of Medicine

Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. chol...



Protective role of autophagy against Vibrio cholerae cytolysin, a pore-forming toxin from V. cholerae  PNAS

Autophagy and autophagy-related pathways in cancer - Nature



Autophagy and autophagy-related pathways in cancer  Nature

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function - PNAS



Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function  PNAS

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...



Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報

The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34...



The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension | Circulation  American Heart Association Journals

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

Autophagy and microbial pathogenesis - Cell Death & Differentiation - Nature



Autophagy and microbial pathogenesis - Cell Death & Differentiation  Nature

Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy - Nature



Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy  Nature

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early...



Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...



HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is...



Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation  PNAS

Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasi...



Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling  Nature

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...



Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

The mTOR–Autophagy Axis and the Control of Metabolism - Frontiers



The mTOR–Autophagy Axis and the Control of Metabolism  Frontiers

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases - Nature



Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases  Nature

Autophagy in healthy aging and disease - Nature



Autophagy in healthy aging and disease  Nature

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation - Nature



Reduction of spermine synthase enhances autophagy to suppress Tau accumulation  Nature

Autophagy: An Intracellular Degradation Pathway Regulating Plant Survival and Stress Response - F...



Autophagy: An Intracellular Degradation Pathway Regulating Plant Survival and Stress Response  Frontiers

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can...



Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from?  Nature

Next questions in autophagy - Nature



Next questions in autophagy  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature