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Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS



ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Autophagy angle sharpens Anavex’s investment case for Alzheimer’s - Longevity.Technology



Autophagy angle sharpens Anavex’s investment case for Alzheimer’s  Longevity.Technology

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...



Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...



The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with a...



Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age  Nature

Tetrandrine-driven autophagy suppresses SARS-CoV-2 replication by modulating cholesterol and IGF ...



Tetrandrine-driven autophagy suppresses SARS-CoV-2 replication by modulating cholesterol and IGF signaling pathways  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...



Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

The Japan autophagy consortium - Nature



The Japan autophagy consortium  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...



Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosom...



Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formation  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...



Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Sodium butyrate-induced autophagy in colorectal cancer unveils the Ca²⁺/CaMKKβ signaling pathway ...



Sodium butyrate-induced autophagy in colorectal cancer unveils the Ca²⁺/CaMKKβ signaling pathway as a potential therapeutic target  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature



Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...



Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...



SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche o...



DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma  Nature

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β...



Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...



Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...



Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature



Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Autophagy as a potential therapeutic target in regulating improper cellular proliferation - Front...



Autophagy as a potential therapeutic target in regulating improper cellular proliferation  Frontiers

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...



PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy - PNAS



Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy  PNAS

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST...



Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST)  PNAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scienti...



Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scientific Reports  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis in...



Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature



Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

Autophagy: Regulator of cell death - Nature



Autophagy: Regulator of cell death  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

The mTOR–Autophagy Axis and the Control of Metabolism - Frontiers



The mTOR–Autophagy Axis and the Control of Metabolism  Frontiers

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

Next questions in autophagy - Nature



Next questions in autophagy  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...



Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease - Frontiers



Editorial: Autophagy: unveiling the mechanisms and implications in health and disease  Frontiers

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...



LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature



Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Self-Eating Decisions - Harvard Medical School



Self-Eating Decisions  Harvard Medical School

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can...



Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from?  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature