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A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardi...



A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs  Frontiers

Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling ...



Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling and transcription activator Met4  Nature.com

Occupational agents-mediated asthma: From the perspective of autophagy - ScienceDirect.com



Occupational agents-mediated asthma: From the perspective of autophagy  ScienceDirect.com

Autophagy's hidden drivers: Exploring the role of post-translational modifications - Science



Autophagy's hidden drivers: Exploring the role of post-translational modifications  Science

Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches - Fron...



Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches  Frontiers

Spermidine is essential for fasting-mediated autophagy and longevity - Nature.com



Spermidine is essential for fasting-mediated autophagy and longevity  Nature.com

Autophagy modulates Arabidopsis male gametophyte fertility and controls actin organization - Natu...



Autophagy modulates Arabidopsis male gametophyte fertility and controls actin organization  Nature.com

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature.com



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature.com

Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance - Nature.com



Stenosing Crohn’s disease patients display gut autophagy/oxidative stress imbalance  Nature.com

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature.com

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy - Nature...



Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy  Nature.com

Ubiquitin regulatory X (UBX) domain-containing protein 6 is essential for autophagy induction and...



Ubiquitin regulatory X (UBX) domain-containing protein 6 is essential for autophagy induction and inflammation control in macrophages  Nature.com

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature.com



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature.com

Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice - Nature.com



Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice  Nature.com

Autophagy modulation attenuates sorafenib resistance in HCC induced in rats - Nature.com



Autophagy modulation attenuates sorafenib resistance in HCC induced in rats  Nature.com

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature.com



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature.com

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...



Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature.com

Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK ...



Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK signaling  Nature.com

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature.com



The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature.com

The SIRT2-AMPK axis regulates autophagy induced by acute liver failure - Nature.com



The SIRT2-AMPK axis regulates autophagy induced by acute liver failure  Nature.com

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Natur...



Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature.com

REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-med...



REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma  Nature.com

An E3 ligase and autophagy adaptor regulates tau proteostasis through nested phase separation - N...



An E3 ligase and autophagy adaptor regulates tau proteostasis through nested phase separation  Nature.com

TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress - Nature.com



TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress  Nature.com

Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research ...



Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research  Nature.com

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy - Nature.com



Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy  Nature.com

Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous ce...



Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous cell carcinoma  Nature.com

Autophagy and hepatic lipid metabolism: mechanistic insight and therapeutic potential for MASLD -...



Autophagy and hepatic lipid metabolism: mechanistic insight and therapeutic potential for MASLD  Nature.com

NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical c...



NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling  Nature.com

Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s dise...



Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease  Molecular Neurodegeneration

Autophagy in Multiple Sclerosis: Two Sides of the Same Coin - Frontiers



Autophagy in Multiple Sclerosis: Two Sides of the Same Coin  Frontiers

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...



HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature.com

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases - Nature.com



Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases  Nature.com

Novel platinum nanoclusters (Pt NCs) induce mitochondrial apoptosis and damaging autophagy for th...



Novel platinum nanoclusters (Pt NCs) induce mitochondrial apoptosis and damaging autophagy for the treatment of osteosarcoma—from the perspective of P53 mutation status in different cell lines  Nature.com

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation | Cell Death & Dis...



Reduction of spermine synthase enhances autophagy to suppress Tau accumulation | Cell Death & Disease  Nature.com

The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessu...



The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessus by activating transcription factor EB  ScienceDirect.com

Plekhm2 acts as an autophagy modulator in murine heart and cardiofibroblasts - Nature.com



Plekhm2 acts as an autophagy modulator in murine heart and cardiofibroblasts  Nature.com

PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma vi...



PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway | Cell Death & Disease  Nature.com

Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney...



Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis  Nature.com

TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DN...



TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA  Nature.com

USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during can...



USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy  Nature.com

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature.com

Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System - Frontiers



Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System  Frontiers

MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy - Nature.com



MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy  Nature.com

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...



Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature.com

Natural autophagy modulators in non-communicable diseases: from autophagy mechanisms to therapeut...



Natural autophagy modulators in non-communicable diseases: from autophagy mechanisms to therapeutic potential  Nature.com

Autophagy Modulators in Coronavirus Diseases: A Double Strike in Viral Burden and Inflammation - ...



Autophagy Modulators in Coronavirus Diseases: A Double Strike in Viral Burden and Inflammation  Frontiers

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition...



Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells | Cell Death & Disease  Nature.com

Autophagy: A potential target for natural products in the treatment of ulcerative colitis - Scien...



Autophagy: A potential target for natural products in the treatment of ulcerative colitis  ScienceDirect.com

IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury...



IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure  Nature.com

Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied f...



Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied for regenerative medicine  Nature.com

The emerging roles of miRNA-mediated autophagy in ovarian cancer - Nature.com



The emerging roles of miRNA-mediated autophagy in ovarian cancer  Nature.com

Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR p...



Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN  ScienceDirect.com

Student-Led Research Reveals “Off-Switch” for Autophagy - College of Biological Sciences



Student-Led Research Reveals “Off-Switch” for Autophagy  College of Biological Sciences

Inhibition of autophagy; an opportunity for the treatment of cancer resistance - Frontiers



Inhibition of autophagy; an opportunity for the treatment of cancer resistance  Frontiers

A potential strategy for bladder cancer treatment: inhibiting autophagy to enhance antitumor effe...



A potential strategy for bladder cancer treatment: inhibiting autophagy to enhance antitumor effects of Nectin-4-MMAE  Nature.com

Molecular mechanism of autophagy in porcine reproductive and respiratory syndrome virus infection...



Molecular mechanism of autophagy in porcine reproductive and respiratory syndrome virus infection  Frontiers

Propolis as an autophagy modulator in relation to its roles in redox balance and inflammation reg...



Propolis as an autophagy modulator in relation to its roles in redox balance and inflammation regulation  ScienceDirect.com

Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid...



Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia  Nature.com

Hypoxia enhances autophagy level of human sperms - Nature.com



Hypoxia enhances autophagy level of human sperms  Nature.com

OPN silencing reduces hypoxic pulmonary hypertension via PI3K-AKT-induced protective autophagy - ...



OPN silencing reduces hypoxic pulmonary hypertension via PI3K-AKT-induced protective autophagy  Nature.com

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature.com

The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skelet...



The autophagy inhibitor NSC185058 suppresses mTORC1-mediated protein anabolism in cultured skeletal muscle  Nature.com

Autophagy-mediated degradation of integumentary tapetum is critical for embryo pattern formation ...



Autophagy-mediated degradation of integumentary tapetum is critical for embryo pattern formation  Nature.com

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature.com



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature.com

Attenuation of phytofungal pathogenicity of Ascomycota by autophagy modulators - Nature.com



Attenuation of phytofungal pathogenicity of Ascomycota by autophagy modulators  Nature.com

Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis in...



Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice  Nature.com

Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy - Natur...



Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy  Nature.com

Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral ass...



Human cytomegalovirus degrades DMXL1 to inhibit autophagy, lysosomal acidification, and viral assembly  ScienceDirect.com

Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidat...



Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity  Nature.com

Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMP...



Glutamine suppresses senescence and promotes autophagy through glycolysis inhibition-mediated AMPKα lactylation in intervertebral disc degeneration  Nature.com

ADT-OH exhibits anti-metastatic activity on triple-negative breast cancer by combinatorial target...



ADT-OH exhibits anti-metastatic activity on triple-negative breast cancer by combinatorial targeting of autophagy and mitochondrial fission  Nature.com

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms throug...



BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking | Communications Biology  Nature.com

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia - Nature.com



Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia  Nature.com

p66Shc signaling and autophagy impact on C2C12 myoblast differentiation during senescence | Cell ...



p66Shc signaling and autophagy impact on C2C12 myoblast differentiation during senescence | Cell Death & Disease  Nature.com

Autophagy as a new player in the regulation of clock neurons physiology of Drosophila melanogaste...



Autophagy as a new player in the regulation of clock neurons physiology of Drosophila melanogaster  Nature.com

Exposure to polystyrene nanoplastics induces apoptosis, autophagy, histopathological damage, and ...



Exposure to polystyrene nanoplastics induces apoptosis, autophagy, histopathological damage, and intestinal microbiota dysbiosis of the Pacific whiteleg shrimp ( Litopenaeus vannamei  ScienceDirect.com

A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy - Nature.com



A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy  Nature.com

Autophagy-related gene model as a novel risk factor for schizophrenia | Translational Psychiatry ...



Autophagy-related gene model as a novel risk factor for schizophrenia | Translational Psychiatry  Nature.com

Autophagy and the Bone Marrow Microenvironment: A Review of Protective Factors in the Development...



Autophagy and the Bone Marrow Microenvironment: A Review of Protective Factors in the Development and Maintenance of Multiple Myeloma  Frontiers

Crosstalk of cell death pathways unveils an autophagy-related gene AOC3 as a critical prognostic ...



Crosstalk of cell death pathways unveils an autophagy-related gene AOC3 as a critical prognostic marker in colorectal cancer | Communications Biology  Nature.com

G-quadruplexes in MTOR and induction of autophagy - Nature.com



G-quadruplexes in MTOR and induction of autophagy  Nature.com

Regulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity - Nature.com



Regulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity  Nature.com

Natural products targeting autophagy and apoptosis in NSCLC: a novel therapeutic strategy - Front...



Natural products targeting autophagy and apoptosis in NSCLC: a novel therapeutic strategy  Frontiers

The role of autophagy in prostate cancer and prostatic diseases: a new therapeutic strategy - Nat...



The role of autophagy in prostate cancer and prostatic diseases: a new therapeutic strategy  Nature.com

Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy - Nature...



Molecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy  Nature.com

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers



Interplay Between NLRP3 Inflammasome and Autophagy  Frontiers

Petal abscission is promoted by jasmonic acid-induced autophagy at Arabidopsis petal bases - Natu...



Petal abscission is promoted by jasmonic acid-induced autophagy at Arabidopsis petal bases  Nature.com

Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-m...



Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway  Journal of Translational Medicine

neutrophils with dysfunctional autophagy establish systemic immunosuppression by increasing regul...



neutrophils with dysfunctional autophagy establish systemic immunosuppression by increasing regulatory T cells  Nature.com

Ubiquitin in autophagy and non-protein ubiquitination - Nature.com



Ubiquitin in autophagy and non-protein ubiquitination  Nature.com

Autophagy and Skin Diseases - Frontiers



Autophagy and Skin Diseases  Frontiers

LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency...



LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis  Nature.com

Upregulated pexophagy limits the capacity of selective autophagy - Nature.com



Upregulated pexophagy limits the capacity of selective autophagy  Nature.com

Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targetin...



Analysis of autophagy in DLBCL reveals subtype-specific differences and the preferential targeting of ULK1 inhibition in GCB-DLBCL provides a rationale as a new therapeutic approach | Leukemia  Nature.com

Starvation and exercise stimulate autophagy via a novel lysosomal signaling mechanism - Texas Chi...



Starvation and exercise stimulate autophagy via a novel lysosomal signaling mechanism  Texas Children’s

Crosstalk between autophagy and metabolism: implications for cell survival in acute myeloid leuke...



Crosstalk between autophagy and metabolism: implications for cell survival in acute myeloid leukemia  Nature.com

The role of autophagy in the treatment of type II diabetes and its complications: a review - Fron...



The role of autophagy in the treatment of type II diabetes and its complications: a review  Frontiers

Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dy...



Transcriptional dysregulation of autophagy in the muscle of a mouse model of Duchenne muscular dystrophy  Nature.com

Lactate-induced autophagy activation: unraveling the therapeutic impact of high-intensity interva...



Lactate-induced autophagy activation: unraveling the therapeutic impact of high-intensity interval training on insulin resistance in type 2 diabetic rats  Nature.com