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‘Breakthrough Science’ grant supports disease-targeting lipid research - Cornell Chronicle



‘Breakthrough Science’ grant supports disease-targeting lipid research  Cornell Chronicle

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Rab GTPases are evolutionarily conserved signals mediating selective autophagy - Rockefeller Univ...



Rab GTPases are evolutionarily conserved signals mediating selective autophagy  Rockefeller University Press

Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast ...



Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse  Science | AAAS

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...



Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries - Nature



Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature



Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...



Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience - Nature



Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature



PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outsi...



The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling  Nature

Chemically engineered antibodies for autophagy-based receptor degradation - Nature



Chemically engineered antibodies for autophagy-based receptor degradation  Nature

USP24 promotes autophagy-dependent ferroptosis in hepatocellular carcinoma by reducing the K48-li...



USP24 promotes autophagy-dependent ferroptosis in hepatocellular carcinoma by reducing the K48-linked ubiquitination of Beclin1  Nature

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like prot...



A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope  Nature

ATG8 delipidation is not universally critical for autophagy in plants - Nature



ATG8 delipidation is not universally critical for autophagy in plants  Nature

Polystyrene nanoplastics promote the blood-brain barrier dysfunction through autophagy pathway an...



Polystyrene nanoplastics promote the blood-brain barrier dysfunction through autophagy pathway and excessive erythrophagocytosis  ScienceDirect.com

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress - Nature



Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress  Nature

Exercise-driven cellular autophagy: A bridge to systematic wellness - ScienceDirect.com



Exercise-driven cellular autophagy: A bridge to systematic wellness  ScienceDirect.com

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival - Scienc...



TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival  ScienceDirect.com

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy - Nature



Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization - Science...



The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization  ScienceDirect.com

Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling ...



Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling and transcription activator Met4  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice - Nature



Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice  Nature

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy - Nature



Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy  Nature

The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessu...



The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessus by activating transcription factor EB  ScienceDirect.com

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases - Nature



Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases  Nature

A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardi...



A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs  Frontiers

Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches - Fron...



Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches  Frontiers

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

Therapeutic effect of nicotinamide mononucleotide on Alzheimer’s disease through activating autop...



Therapeutic effect of nicotinamide mononucleotide on Alzheimer’s disease through activating autophagy and anti-oxidative stress  ScienceDirect.com

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Autophagy Is Required for Strawberry Fruit Ripening - Frontiers



Autophagy Is Required for Strawberry Fruit Ripening  Frontiers

AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treatin...



AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields) | Cell Death & Disease  Nature

Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC...



Discovery of Novel PDEδ Autophagic Degraders: A Case Study of Autophagy-Tethering Compound (ATTEC)  ACS Publications

VCP/p97 regulates Beclin-1-dependent autophagy initiation - Nature



VCP/p97 regulates Beclin-1-dependent autophagy initiation  Nature

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes - Nature



A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes  Nature

Autophagy in Human Diseases - The New England Journal of Medicine



Autophagy in Human Diseases  The New England Journal of Medicine

BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stre...



BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration  Nature

TOR ‐mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly - EMBO Press



TOR ‐mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly  EMBO Press

Mechanism of neuroprotection by trehalose: controversy surrounding autophagy induction - Nature



Mechanism of neuroprotection by trehalose: controversy surrounding autophagy induction  Nature

USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during can...



USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy  Nature

Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment - Nature



Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment  Nature

Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stro...



Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stroke via autophagy regulation  ScienceDirect.com

Tumor necrosis factor α-induced protein 3 mediates inflammation and neuronal autophagy in Parkins...



Tumor necrosis factor α-induced protein 3 mediates inflammation and neuronal autophagy in Parkinson’s disease via the NFκB and mTOR pathways  ScienceDirect.com

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-dri...



Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers  Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature



Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

eIF5A is required for autophagy by mediating ATG3 translation | EMBO reports - EMBO Press



eIF5A is required for autophagy by mediating ATG3 translation | EMBO reports  EMBO Press

Regulation of autophagy by microRNAs in human breast cancer - Journal of Biomedical Science



Regulation of autophagy by microRNAs in human breast cancer  Journal of Biomedical Science

Autophagy regulates lipid metabolism through selective turnover of NCoR1 - Nature



Autophagy regulates lipid metabolism through selective turnover of NCoR1  Nature

β-Hydroxybutyric Inhibits Vascular Calcification via Autophagy Enhancement in Models Induced by H...



β-Hydroxybutyric Inhibits Vascular Calcification via Autophagy Enhancement in Models Induced by High Phosphate  Frontiers

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...



PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...



Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

Autophagy promotes cell survival by maintaining NAD levels - ScienceDirect.com



Autophagy promotes cell survival by maintaining NAD levels  ScienceDirect.com

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

The Hedgehog signalling pathway regulates autophagy - Nature



The Hedgehog signalling pathway regulates autophagy  Nature

Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s dise...



Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease  Molecular Neurodegeneration

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Autophagy: Regulator of cell death - Cell Death & Disease - Nature



Autophagy: Regulator of cell death - Cell Death & Disease  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Selectivity of mRNA degradation by autophagy in yeast - Nature



Selectivity of mRNA degradation by autophagy in yeast  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation - ACS...



Autophagy Receptor-Inspired Antibody-Fusion Proteins for Targeted Intracellular Degradation  ACS Publications

Metformin prevents cell tumorigenesis through autophagy-related cell death - Nature



Metformin prevents cell tumorigenesis through autophagy-related cell death  Nature

Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research ...



Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research  Nature

The different autophagy degradation pathways and neurodegeneration - ScienceDirect.com



The different autophagy degradation pathways and neurodegeneration  ScienceDirect.com

AUTACs: Cargo-Specific Degraders Using Selective Autophagy - ScienceDirect.com



AUTACs: Cargo-Specific Degraders Using Selective Autophagy  ScienceDirect.com

lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation - Nature



lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation  Nature

Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fue...



Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research  PNAS

Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome - ScienceDirec...



Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome  ScienceDirect.com

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Autophagy as a therapeutic target in pancreatic cancer - Nature



Autophagy as a therapeutic target in pancreatic cancer  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Systematically defining selective autophagy receptor-specific cargo using autophagosome content p...



Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling  ScienceDirect.com

A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neuro...



A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons  Acta Neuropathologica Communications

USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin‐1 | The EMBO ...



USP19 modulates autophagy and antiviral immune responses by deubiquitinating Beclin‐1 | The EMBO Journal  EMBO Press

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

Autophagy in kidney homeostasis and disease - Nature



Autophagy in kidney homeostasis and disease  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature