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Autophagy modulation in cancer - Nature



Autophagy modulation in cancer  Nature

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers



Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

Regulation of STK38 by autophagy governs YAP1 activity during paligenosis - PNAS



Regulation of STK38 by autophagy governs YAP1 activity during paligenosis  PNAS

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy - Rockefeller Univer...



Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy  Rockefeller University Press

Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar ...



Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6  Nature

Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases - Frontiers



Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases  Frontiers

TBK1 restricts IRGQ-mediated autophagy - Nature



TBK1 restricts IRGQ-mediated autophagy  Nature

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activatio...



Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activation across multiple isogenic models  Nature

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...



A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Translation in proximity to forming autophagosomes during sustained autophagy - Nature



Translation in proximity to forming autophagosomes during sustained autophagy  Nature

Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in...



Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in Arabidopsis thaliana  Nature

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chem...



TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chemotherapy efficacy  Nature

PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion - Nature



PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion  Nature

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeut...



Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeutic targeting  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature



A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...



Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...



A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Autophagy in ocular diseases: from mechanisms to therapeutic potential - Frontiers



Autophagy in ocular diseases: from mechanisms to therapeutic potential  Frontiers

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways - Frontiers



Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways  Frontiers

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...



The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development - Frontiers



Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development  Frontiers

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...



SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Historical landmarks of autophagy research - Nature



Historical landmarks of autophagy research  Nature

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...



Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...



Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Impact of context-dependent autophagy states on tumor progression - Nature



Impact of context-dependent autophagy states on tumor progression  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension...



The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension  American Heart Association Journals

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS



Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature



A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...



Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...



TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Autophagy as a promoter of longevity: insights from model organisms - Nature



Autophagy as a promoter of longevity: insights from model organisms  Nature

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy - Science | AAAS



Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy  Science | AAAS

Activating Autophagy to Prevent Doxorubicin Cardiomyopathy: The Timing Matters - American Heart A...



Activating Autophagy to Prevent Doxorubicin Cardiomyopathy: The Timing Matters  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy regulation by RNA alternative splicing and implications in human diseases - Nature



Autophagy regulation by RNA alternative splicing and implications in human diseases  Nature

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Cellular quality control by the ubiquitin-proteasome system and autophagy - Science | AAAS



Cellular quality control by the ubiquitin-proteasome system and autophagy  Science | AAAS

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS



Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals



Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai



Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy - Nature



Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature



Autophagy promotes jasmonate-mediated defense against nematodes  Nature

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals ...



SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals  Nature

The Nobel Prize in Physiology or Medicine 2016 - Press release - NobelPrize.org



The Nobel Prize in Physiology or Medicine 2016 - Press release  NobelPrize.org

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature



Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

Rab GTPases are evolutionarily conserved signals mediating selective autophagy - Rockefeller Univ...



Rab GTPases are evolutionarily conserved signals mediating selective autophagy  Rockefeller University Press

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature



Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ...



TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress  Nature

NBR1: The archetypal selective autophagy receptor - Rockefeller University Press



NBR1: The archetypal selective autophagy receptor  Rockefeller University Press

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...



Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine