Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzh...

Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer’s Disease  Anavex Life Sciences

Autophagy-dependent disruption of β-FAO-mediated histone acetylation in embryos during maternal a...

Autophagy-dependent disruption of β-FAO-mediated histone acetylation in embryos during maternal aging  ScienceDirect.com

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidatio...

AMPK affects the development of early-stage NAFLD by activating autophagy and fatty acid oxidation  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticle...

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Phagoflux: From Research to Cutting-Edge Autophagy Solutions - Stellenbosch University

Phagoflux: From Research to Cutting-Edge Autophagy Solutions  Stellenbosch University

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

First “teaching textbook” on autophagy now available - Stellenbosch University

First “teaching textbook” on autophagy now available  Stellenbosch University

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Autophagy: Definition, Diet, Fasting, Cancer, Benefits, and More - Healthline

Autophagy: Definition, Diet, Fasting, Cancer, Benefits, and More  Healthline

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals

Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses | Scientific Reports  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Autophagy in healthy aging and disease - Nature

Autophagy in healthy aging and disease  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature

Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis in...

Autophagy promotes efficient T cell responses to restrict high-dose Mycobacterium tuberculosis infection in mice  Nature

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human gen...

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics  PNAS

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinop...

Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Next questions in autophagy - Nature

Next questions in autophagy  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - NEJM

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  NEJM

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early...

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature

Redefining the role of AMPK in autophagy and the energy stress response  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

ATPase activity of DFCP1 controls selective autophagy - Nature

ATPase activity of DFCP1 controls selective autophagy  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Defective autophagy leads to cancer - ScienceDirect.com

Defective autophagy leads to cancer  ScienceDirect.com

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histo...

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Impact of context-dependent autophagy states on tumor progression - Nature

Impact of context-dependent autophagy states on tumor progression  Nature

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences

Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature

Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasi...

Autophagy inhibition prevents lymphatic malformation progression to lymphangiosarcoma by decreasing osteopontin and Stat3 signaling  Nature

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition...

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells | Cell Death & Disease  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS

Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Autophagy promotes jasmonate-mediated defense against nematodes - Nature

Autophagy promotes jasmonate-mediated defense against nematodes  Nature