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A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...



A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - pnas.org



ER membrane receptors engage core autophagy machinery to initiate ER-phagy  pnas.org

Autophagy-dependent disruption of β-FAO-mediated histone acetylation in embryos during maternal a...



Autophagy-dependent disruption of β-FAO-mediated histone acetylation in embryos during maternal aging  ScienceDirect.com

Scientists map autophagy in fruit flies, key for egg development | Tap to know more | Inshorts - ...



Scientists map autophagy in fruit flies, key for egg development | Tap to know more | Inshorts  Inshorts

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...



The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  pnas.org

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...



Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - pna...



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  pnas.org

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Al...



Microglia-derived nanovesicles synchronize macroautophagy and chaperone-mediated autophagy for Alzheimer’s disease therapy  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

The Japan autophagy consortium - Nature



The Japan autophagy consortium  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...



Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature



Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Programmable targeted RNA degradation via dCas13d-directed chaperone-mediated autophagy (dCasCMA)...



Programmable targeted RNA degradation via dCas13d-directed chaperone-mediated autophagy (dCasCMA)  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature



Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

CAFs exosomal circFOXO1 promotes TNBC autophagy and radioresistance via miR-27a-3p/BNIP3 axis - N...



CAFs exosomal circFOXO1 promotes TNBC autophagy and radioresistance via miR-27a-3p/BNIP3 axis  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...



Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...



SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  utsouthwestern.edu

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  pnas.org

Modulating ovarian cancer progression through FDX1-driven autophagy - Nature



Modulating ovarian cancer progression through FDX1-driven autophagy  Nature

Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in genta...



Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - pnas...



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  pnas.org

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...



Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...



Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature



Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

The Beth Levine, M.D. Prize in Autophagy Research - utsouthwestern.edu



The Beth Levine, M.D. Prize in Autophagy Research  utsouthwestern.edu

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  pnas.org

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...



LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses | Scientific Reports  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Next questions in autophagy - Nature



Next questions in autophagy  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai



Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Autophagy: Regulator of cell death - Nature



Autophagy: Regulator of cell death  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy is part of the answer to tuberculosis - Nature



Autophagy is part of the answer to tuberculosis  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - pnas.org



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  pnas.org

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...



Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Self-Eating Decisions - Harvard Medical School



Self-Eating Decisions  Harvard Medical School

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature



Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  pnas.org

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com



Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Autophagy in tumour immunity and therapy - Nature



Autophagy in tumour immunity and therapy  Nature

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences



Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...



Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition...



Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells | Cell Death & Disease  Nature

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature



The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...



Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報