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Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast ...



Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse  Science | AAAS

Integrated multiomics analysis identifies potential biomarkers and therapeutic targets for autoph...



Integrated multiomics analysis identifies potential biomarkers and therapeutic targets for autophagy associated AKI to CKD transition  Nature

Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches - Fron...



Autophagy in spinal muscular atrophy: from pathogenic mechanisms to therapeutic approaches  Frontiers

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...



Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardi...



A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs  Frontiers

Multi-omics study reveals differential expression and phosphorylation of autophagy-related protei...



Multi-omics study reveals differential expression and phosphorylation of autophagy-related proteins in autism spectrum disorder  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology - Nature



Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation - Nature



ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells ...



Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells  Nature

Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombo...



Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombosis  Nature

Role of TRIM24 in the regulation of proteasome-autophagy crosstalk in bortezomib-resistant mantle...



Role of TRIM24 in the regulation of proteasome-autophagy crosstalk in bortezomib-resistant mantle cell lymphoma  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outsi...



The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling  Nature

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like prot...



A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope  Nature

Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience - Nature



Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature



PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

Chemically engineered antibodies for autophagy-based receptor degradation - Nature



Chemically engineered antibodies for autophagy-based receptor degradation  Nature

ATG8 delipidation is not universally critical for autophagy in plants - Nature



ATG8 delipidation is not universally critical for autophagy in plants  Nature

Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling ...



Sulfur starvation-induced autophagy in Saccharomyces cerevisiae involves SAM-dependent signaling and transcription activator Met4  Nature

Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melan...



Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Autophagy modulates Arabidopsis male gametophyte fertility and controls actin organization - Nature



Autophagy modulates Arabidopsis male gametophyte fertility and controls actin organization  Nature

Women in Autophagy: an initiative to promote gender parity in science - Nature



Women in Autophagy: an initiative to promote gender parity in science  Nature

Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress - Nature



Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress  Nature

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Autophagy's hidden drivers: Exploring the role of post-translational modifications - Science | AAAS



Autophagy's hidden drivers: Exploring the role of post-translational modifications  Science | AAAS

Scientists uncover key factors for starting autophagy in cells - News-Medical



Scientists uncover key factors for starting autophagy in cells  News-Medical

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction - Science | ...



Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction  Science | AAAS

The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization - Science...



The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization  ScienceDirect.com

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature



Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Alternative mRNA polyadenylation regulates macrophage hyperactivation via the autophagy pathway -...



Alternative mRNA polyadenylation regulates macrophage hyperactivation via the autophagy pathway  Nature

Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK ...



Heme deficiency in skeletal muscle exacerbates sarcopenia and impairs autophagy by reducing AMPK signaling  Nature

Targeting chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapeutic ...



Targeting chaperone-mediated autophagy in neurodegenerative diseases: mechanisms and therapeutic potential  Nature

Amantadine against glioma via ROS-mediated apoptosis and autophagy arrest | Cell Death & Disease ...



Amantadine against glioma via ROS-mediated apoptosis and autophagy arrest | Cell Death & Disease  Nature

Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in...



Modulating autophagy to boost the antitumor efficacy of TROP2-directed antibody-drug conjugate in pancreatic cancer  ScienceDirect.com

Integrated analysis ceRNA network of autophagy-related gene RNF144B in steroid-induced necrosis o...



Integrated analysis ceRNA network of autophagy-related gene RNF144B in steroid-induced necrosis of the femoral head  Nature

Ubiquitin regulatory X (UBX) domain-containing protein 6 is essential for autophagy induction and...



Ubiquitin regulatory X (UBX) domain-containing protein 6 is essential for autophagy induction and inflammation control in macrophages  Nature

STING orchestrates microglia polarization via interaction with LC3 in autophagy after ischemia | ...



STING orchestrates microglia polarization via interaction with LC3 in autophagy after ischemia | Cell Death & Disease  Nature

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy - Nature



Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice - Nature



Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice  Nature

Autophagy modulation attenuates sorafenib resistance in HCC induced in rats - Nature



Autophagy modulation attenuates sorafenib resistance in HCC induced in rats  Nature

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can...



Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from?  Nature

Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism i...



Autophagy mediates the impact of Porphyromonas gingivalis on short-chain fatty acids metabolism in periodontitis-induced gut dysbiosis  Nature

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy - Nature



Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy  Nature

NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical c...



NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling  Nature

TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress - Nature



TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress  Nature

Autophagy and Stem Cells: Self-Eating for Self-Renewal - Frontiers



Autophagy and Stem Cells: Self-Eating for Self-Renewal  Frontiers

Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy allevi...



Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice | Bone Research  Nature

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases - Nature



Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases  Nature

The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessu...



The autophagy-targeting compound V46 enhances antimicrobial responses to Mycobacteroides abscessus by activating transcription factor EB  ScienceDirect.com

Autophagy and hepatic lipid metabolism: mechanistic insight and therapeutic potential for MASLD -...



Autophagy and hepatic lipid metabolism: mechanistic insight and therapeutic potential for MASLD  Nature

Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous ce...



Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous cell carcinoma  Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature



Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

The SIRT2-AMPK axis regulates autophagy induced by acute liver failure - Nature



The SIRT2-AMPK axis regulates autophagy induced by acute liver failure  Nature

Autophagy in Multiple Sclerosis: Two Sides of the Same Coin - Frontiers



Autophagy in Multiple Sclerosis: Two Sides of the Same Coin  Frontiers

The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation - Nature



The autophagy adaptor TRIAD3A promotes tau fibrillation by nested phase separation  Nature

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy - PNAS



Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy  PNAS

Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging - Frontiers



Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging  Frontiers

Therapeutic effect of nicotinamide mononucleotide on Alzheimer’s disease through activating autop...



Therapeutic effect of nicotinamide mononucleotide on Alzheimer’s disease through activating autophagy and anti-oxidative stress  ScienceDirect.com

Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System - Frontiers



Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System  Frontiers

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Autophagy Modulators in Coronavirus Diseases: A Double Strike in Viral Burden and Inflammation - ...



Autophagy Modulators in Coronavirus Diseases: A Double Strike in Viral Burden and Inflammation  Frontiers

Ferulic acid restores mitochondrial dynamics and autophagy via AMPK signaling pathway in a palmit...



Ferulic acid restores mitochondrial dynamics and autophagy via AMPK signaling pathway in a palmitate-induced hepatocyte model of metabolic syndrome  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...



Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-med...



REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma | Scientific Reports  Nature

Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research ...



Differences in autophagy marker levels at birth in preterm vs. term infants | Pediatric Research  Nature

Autophagy: A potential target for natural products in the treatment of ulcerative colitis - Scien...



Autophagy: A potential target for natural products in the treatment of ulcerative colitis  ScienceDirect.com

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...



HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s dise...



Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease  Molecular Neurodegeneration

Inhibition of autophagy; an opportunity for the treatment of cancer resistance - Frontiers



Inhibition of autophagy; an opportunity for the treatment of cancer resistance  Frontiers

Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor acti...



Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers  JCI.org

Perfluoroalkyl sulfonate induces cardiomyocyte apoptosis via endoplasmic reticulum stress activat...



Perfluoroalkyl sulfonate induces cardiomyocyte apoptosis via endoplasmic reticulum stress activation and autophagy flux inhibition  ScienceDirect.com

MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy - Nature



MLKL promotes hepatocarcinogenesis through inhibition of AMPK-mediated autophagy  Nature

TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DN...



TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA  Nature

Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied f...



Atg7 autophagy-independent role on governing neural stem cell fate could be potentially applied for regenerative medicine  Nature

Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney...



Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis  Nature

IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury...



IRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure  Nature

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation | Cell Death & Dis...



Reduction of spermine synthase enhances autophagy to suppress Tau accumulation | Cell Death & Disease  Nature

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition...



Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells | Cell Death & Disease  Nature

New insights into the interplay between autophagy, gut microbiota and insulin resistance in metab...



New insights into the interplay between autophagy, gut microbiota and insulin resistance in metabolic syndrome  ScienceDirect.com

The emerging roles of miRNA-mediated autophagy in ovarian cancer | Cell Death & Disease - Nature



The emerging roles of miRNA-mediated autophagy in ovarian cancer | Cell Death & Disease  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Autophagy and cancer: Can tetrandrine be a potent anticancer drug in the near future? - ScienceDi...



Autophagy and cancer: Can tetrandrine be a potent anticancer drug in the near future?  ScienceDirect.com

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy Is Required for Strawberry Fruit Ripening - Frontiers



Autophagy Is Required for Strawberry Fruit Ripening  Frontiers

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

VCP/p97 regulates Beclin-1-dependent autophagy initiation - Nature



VCP/p97 regulates Beclin-1-dependent autophagy initiation  Nature

USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during can...



USP24-i-101 targeting of USP24 activates autophagy to inhibit drug resistance acquired during cancer therapy  Nature