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Selective autophagy in kidney health and disease - Nature



Selective autophagy in kidney health and disease  Nature

Selective autophagy fine-tunes plant immunity to promote cell survival during viral infection - S...



Selective autophagy fine-tunes plant immunity to promote cell survival during viral infection  Science | AAAS

Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases - Frontiers



Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases  Frontiers

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy - Rockefeller Univer...



Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy  Rockefeller University Press

Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therape...



Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities  Nature

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers



Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

Autophagy modulation in cancer - Nature



Autophagy modulation in cancer  Nature

TBK1 restricts IRGQ-mediated autophagy - Nature



TBK1 restricts IRGQ-mediated autophagy  Nature

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...



A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology - Nature



Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology  Nature

Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitoch...



Pathogenic variants in the autophagy-tethering factor EPG5 drive neurodegeneration through mitochondrial dysfunction and innate immune activation  Nature

Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in...



Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in Arabidopsis thaliana  Nature

Translation in proximity to forming autophagosomes during sustained autophagy - Nature



Translation in proximity to forming autophagosomes during sustained autophagy  Nature

DeepDrugDiscovery identifies blood–brain barrier permeable autophagy enhancers for Alzheimer’s di...



DeepDrugDiscovery identifies blood–brain barrier permeable autophagy enhancers for Alzheimer’s disease  Nature

Physiological medium and 3-hydroxybutyrate modulate autophagy-linked organelle remodeling in huma...



Physiological medium and 3-hydroxybutyrate modulate autophagy-linked organelle remodeling in human external urethral sphincter myoblasts  Nature

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chem...



TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chemotherapy efficacy  Nature

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activatio...



Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activation across multiple isogenic models  Nature

PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion - Nature



PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

Nucleophagy is promoted by two autophagy receptors and inhibited by chromatin-nuclear envelope te...



Nucleophagy is promoted by two autophagy receptors and inhibited by chromatin-nuclear envelope tethering in fission yeast  Nature

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeut...



Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeutic targeting  Nature

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

/Starvation and exercise stimulate autophagy via a novel lysosomal signaling mechanism - Texas Ch...



/Starvation and exercise stimulate autophagy via a novel lysosomal signaling mechanism  Texas Children's

Autophagy in plants: molecular mechanisms and roles in abiotic stress responses - Frontiers



Autophagy in plants: molecular mechanisms and roles in abiotic stress responses  Frontiers

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature



Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...



Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature



A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature



Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways - Frontiers



Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways  Frontiers

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development - Frontiers



Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development  Frontiers

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse mod...



Autophagy controls the hippocampal postsynaptic organization and affects cognition in a mouse model of Fragile X syndrome  Nature

Autophagy: the cell’s waste disposal system | AutoClean Project | Results in Brief | H2020 - CORDIS



Autophagy: the cell’s waste disposal system | AutoClean Project | Results in Brief | H2020  CORDIS

Boosting autophagy limits FUS aggregates and early synaptic dysfunction in ALS model - Bioenginee...



Boosting autophagy limits FUS aggregates and early synaptic dysfunction in ALS model  Bioengineer.org

Historical landmarks of autophagy research - Nature



Historical landmarks of autophagy research  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...



SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy and autophagy-related pathways in cancer - Nature



Autophagy and autophagy-related pathways in cancer  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer...



Quinalizarin induces autophagy, apoptosis and mitotic catastrophe in cervical and prostate cancer cells  Nature

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhanceme...



Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement  Nature

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension...



The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension  American Heart Association Journals

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like prot...



A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...



TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences



Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing - Nature



Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature



PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

Autophagy and microbial pathogenesis - Cell Death & Differentiation - Nature



Autophagy and microbial pathogenesis - Cell Death & Differentiation  Nature

Viruses and autophagy: bend, but don’t break - Nature



Viruses and autophagy: bend, but don’t break  Nature

The Nobel Prize in Physiology or Medicine 2016 - Press release - NobelPrize.org



The Nobel Prize in Physiology or Medicine 2016 - Press release  NobelPrize.org

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy - Science | AAAS



Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy  Science | AAAS

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

ATPase activity of DFCP1 controls selective autophagy - Nature



ATPase activity of DFCP1 controls selective autophagy  Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature



A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern

Mechanism and medical implications of mammalian autophagy - Nature



Mechanism and medical implications of mammalian autophagy  Nature

Defective autophagy leads to cancer - ScienceDirect.com



Defective autophagy leads to cancer  ScienceDirect.com

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Modulation of the autophagic pathway inhibits HIV-1 infection in human lymphoid tissue cultured e...



Modulation of the autophagic pathway inhibits HIV-1 infection in human lymphoid tissue cultured ex vivo  Nature

Impact of context-dependent autophagy states on tumor progression - Nature



Impact of context-dependent autophagy states on tumor progression  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature



Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

Autophagy: from phenomenology to molecular understanding in less than a decade - Nature



Autophagy: from phenomenology to molecular understanding in less than a decade  Nature

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS



Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in...



PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice  American Heart Association Journals

Autophagy in mammalian development and differentiation - Nature



Autophagy in mammalian development and differentiation  Nature