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Rapid activation of p62 body-mediated autophagy in human cells under hyperosmotic stress - Nature



Rapid activation of p62 body-mediated autophagy in human cells under hyperosmotic stress  Nature

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeut...



Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeutic targeting  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS



Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature



Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

V-ATPase-dependent induction of selective autophagy - Nature



V-ATPase-dependent induction of selective autophagy  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...



Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...



Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...



Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature



Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis - Nature



The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis  Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries - Nature



Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...



Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...



Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac ...



SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac hypertrophy  Nature

Rab GTPases are evolutionarily conserved signals mediating selective autophagy - Rockefeller Univ...



Rab GTPases are evolutionarily conserved signals mediating selective autophagy  Rockefeller University Press

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...



Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue - Wiley



MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue  Wiley

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature



PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

Retro Bio commences first-in-human trial - Longevity.Technology



Retro Bio commences first-in-human trial  Longevity.Technology

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature



Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology - Nature



Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology  Nature

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outsi...



The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling  Nature

ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation - Nature



ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...



Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...



Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature



Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Exploring Arylidene–Indolinone Ligands of Autophagy Proteins LC3B and GABARAP - ACS Publications



Exploring Arylidene–Indolinone Ligands of Autophagy Proteins LC3B and GABARAP  ACS Publications

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...



Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treatin...



AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields) | Cell Death & Disease  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Historical landmarks of autophagy research - Cell Research - Nature



Historical landmarks of autophagy research - Cell Research  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...



PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Autophagy: Regulator of cell death - Cell Death & Disease - Nature



Autophagy: Regulator of cell death - Cell Death & Disease  Nature

Nonlytic viral spread enhanced by autophagy components - PNAS



Nonlytic viral spread enhanced by autophagy components  PNAS

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers



Interplay Between NLRP3 Inflammasome and Autophagy  Frontiers

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential act...



Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts  Nature

Chemically engineered antibodies for autophagy-based receptor degradation - Nature



Chemically engineered antibodies for autophagy-based receptor degradation  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...



Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheim...



Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease  PNAS

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms throug...



BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking | Communications Biology  Nature

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia - Nature



Autophagy of mucin granules contributes to resolution of airway mucous metaplasia  Nature

Autophagy in Human Diseases - The New England Journal of Medicine



Autophagy in Human Diseases  The New England Journal of Medicine

ATPase activity of DFCP1 controls selective autophagy - Nature



ATPase activity of DFCP1 controls selective autophagy  Nature

The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34...



The aging mouse CNS is protected by an autophagy-dependent microglia population promoted by IL-34  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Redefining the role of AMPK in autophagy and the energy stress response - Nature



Redefining the role of AMPK in autophagy and the energy stress response  Nature

Autophagy and autophagy-related pathways in cancer - Nature



Autophagy and autophagy-related pathways in cancer  Nature

Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps - Frontiers



Autophagy in Neutrophils: From Granulopoiesis to Neutrophil Extracellular Traps  Frontiers

Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases - Nature



Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...



HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Next questions in autophagy - Nature



Next questions in autophagy  Nature

Autophagy as a therapeutic target in pancreatic cancer - Nature



Autophagy as a therapeutic target in pancreatic cancer  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...



Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is...



Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation  PNAS

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Identification of key autophagy-related genes and pathways in spinal cord injury - Nature



Identification of key autophagy-related genes and pathways in spinal cord injury  Nature

The mTOR–Autophagy Axis and the Control of Metabolism - Frontiers



The mTOR–Autophagy Axis and the Control of Metabolism  Frontiers

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation - Nature



Reduction of spermine synthase enhances autophagy to suppress Tau accumulation  Nature

Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction - Science | ...



Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction  Science | AAAS

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...



Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature



Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

In situ snapshots along a mammalian selective autophagy pathway - PNAS



In situ snapshots along a mammalian selective autophagy pathway  PNAS

PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex - PNAS



PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex  PNAS

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature



A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature



Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy  Nature

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature