Time-resolved functional genomics using deep learning reveals global hierarchical control of auto...

Time-resolved functional genomics using deep learning reveals global hierarchical control of autophagy  Nature

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

ER membrane receptors engage core autophagy machinery to initiate ER-phagy - PNAS

ER membrane receptors engage core autophagy machinery to initiate ER-phagy  PNAS

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chem...

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chemotherapy efficacy  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with a...

Chaperone-mediated autophagy sustains muscle stem cell regenerative functions but declines with age  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Targeting mitochondrial autophagy for anti-aging - Nature

Targeting mitochondrial autophagy for anti-aging  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche o...

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Autophagy in aquatic animals: mechanisms, implications, and future directions - Frontiers

Autophagy in aquatic animals: mechanisms, implications, and future directions  Frontiers

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Autophagy as a potential therapeutic target in regulating improper cellular proliferation - Front...

Autophagy as a potential therapeutic target in regulating improper cellular proliferation  Frontiers

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced...

Punicalagin relieves hepatic injury by antioxidation and enhancement of autophagy in diet-induced nonalcoholic steatohepatitis  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press

Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus Cornus officinalis to ...

Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus Cornus officinalis to ameliorate diabetic nephropathy  Frontiers

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Autophagy Is Required for Strawberry Fruit Ripening - Frontiers

Autophagy Is Required for Strawberry Fruit Ripening  Frontiers

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy - PNAS

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy  PNAS

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

The Hedgehog signalling pathway regulates autophagy - Nature

The Hedgehog signalling pathway regulates autophagy  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Next questions in autophagy - Nature

Next questions in autophagy  Nature

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

In situ snapshots along a mammalian selective autophagy pathway - PNAS

In situ snapshots along a mammalian selective autophagy pathway  PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scienti...

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scientific Reports  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

NBR1: The archetypal selective autophagy receptor - Rockefeller University Press

NBR1: The archetypal selective autophagy receptor  Rockefeller University Press

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature

Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Association between autophagy and acute pancreatitis - Frontiers

Association between autophagy and acute pancreatitis  Frontiers

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease - Frontiers

Editorial: Autophagy: unveiling the mechanisms and implications in health and disease  Frontiers

The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B - Rockefeller ...

The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B  Rockefeller University Press

The effect of an exercise- and passive-induced heat stress on autophagy in young and older males ...

The effect of an exercise- and passive-induced heat stress on autophagy in young and older males  American Physiological Society Journal

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Blockade of RAF and autophagy is the one-two punch to take out Ras - PNAS

Blockade of RAF and autophagy is the one-two punch to take out Ras  PNAS

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation - N...

Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Self-Eating Decisions - Harvard Medical School

Self-Eating Decisions  Harvard Medical School

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death ...

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death  PNAS

Enhanced Autophagy Could Help Treat Diabetes - Northwestern University

Enhanced Autophagy Could Help Treat Diabetes  Northwestern University

Student-Led Research Reveals “Off-Switch” for Autophagy - UC Davis College of Biological Sciences

Student-Led Research Reveals “Off-Switch” for Autophagy  UC Davis College of Biological Sciences

PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in...

PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice  American Heart Association Journals

Defective autophagy leads to cancer - ScienceDirect.com

Defective autophagy leads to cancer  ScienceDirect.com

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue - Wiley

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue  Wiley

Wetting regulates autophagy of phase-separated compartments and the cytosol - Nature

Wetting regulates autophagy of phase-separated compartments and the cytosol  Nature

Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo - Nature

Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo  Nature

Staged suppression of microglial autophagy facilitates regeneration in CNS demyelination by enhan...

Staged suppression of microglial autophagy facilitates regeneration in CNS demyelination by enhancing the production of linoleic acid  PNAS

ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation - Sci...

ULK1 forms distinct oligomeric states and nanoscopic structures during autophagy initiation  Science | AAAS

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human gen...

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics  PNAS