Time-resolved functional genomics using deep learning reveals global hierarchical control of auto...

Time-resolved functional genomics using deep learning reveals global hierarchical control of autophagy  Nature

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by pr...

The autophagy-specific exocyst subcomplex contributes to phagophore assembly site integrity by promoting phagophore expansion  PNAS

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature...

Autophagy-regulated mitochondrial inheritance controls early CD8+ T cell fate commitment | Nature Cell Biology  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis - Nature

Piezo1-mediated autophagy promotes immune-inflammatory responses in ankylosing spondylitis  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity - Rocke...

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity  Rockefeller University Press

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy - Nature

A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche o...

DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β...

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia  Nature

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern - Ricerca Ma...

Andrea Ballabio awarded Beth Levine Prize in Autophagy Research from UT Southwestern  Ricerca Malattie Genetiche Rare

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mit...

Radiosensitizing effects of Withaferin A in gastric cancer cells via autophagy Inhibition and mitochondrial disruption  Nature

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Correcting TFEB, FOXO3, TLR4 Roles in Resveratrol Autophagy - Bioengineer.org

Correcting TFEB, FOXO3, TLR4 Roles in Resveratrol Autophagy  Bioengineer.org

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Time-restricted feeding attenuated hypertension-induced cardiac remodeling by modulating autophag...

Time-restricted feeding attenuated hypertension-induced cardiac remodeling by modulating autophagy levels in spontaneously hypertensive rats  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

Autophagy is a promising process for linking inflammation and redox homeostasis in Down syndrome ...

Autophagy is a promising process for linking inflammation and redox homeostasis in Down syndrome  Frontiers

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Autophagy Is Required for Strawberry Fruit Ripening - Frontiers

Autophagy Is Required for Strawberry Fruit Ripening  Frontiers

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy - PNAS

Calorie restriction and calorie-restriction mimetics activate chaperone-mediated autophagy  PNAS

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology - Nature

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis | Communications Biology  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Autophagy in tumour immunity and therapy - Nature

Autophagy in tumour immunity and therapy  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scienti...

Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia | Scientific Reports  Nature

Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary f...

Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease  PNAS

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflamm...

LKB1/p53/TIGAR/autophagy-dependent VEGF expression contributes to PM2.5-induced pulmonary inflammatory responses  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Lipids associated with autophagy: mechanisms and therapeutic targets - Nature

Lipids associated with autophagy: mechanisms and therapeutic targets  Nature

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature

USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

Autophagy: Regulator of cell death - Nature

Autophagy: Regulator of cell death  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App kno...

Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models  Nature

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early...

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons  Nature

Next questions in autophagy - Nature

Next questions in autophagy  Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses - Nature

Membrane-assisted assembly and selective secretory autophagy of enteroviruses  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during...

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging  Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic...

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature