Autophagy modulation in cancer - Nature

Autophagy modulation in cancer  Nature

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy - Rockefeller Univer...

Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy  Rockefeller University Press

Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar ...

Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6  Nature

Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases - Frontiers

Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases  Frontiers

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activatio...

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activation across multiple isogenic models  Nature

Translation in proximity to forming autophagosomes during sustained autophagy - Nature

Translation in proximity to forming autophagosomes during sustained autophagy  Nature

Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in...

Cell-type-specific autophagy in root-hair-forming cells is essential for salt stress tolerance in Arabidopsis thaliana  Nature

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion - Nature

PINK1 and STUB1 pathway orchestrates peroxisomal selective autophagy by PEX13 depletion  Nature

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chem...

TOLLIP targets GSDME-NT-carrying endocytic vesicles for autophagy to regulate pyroptosis and chemotherapy efficacy  Nature

Core principles of autophagy initiation mechanisms - Nature

Core principles of autophagy initiation mechanisms  Nature

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeut...

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeutic targeting  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature

Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Autophagy in ocular diseases: from mechanisms to therapeutic potential - Frontiers

Autophagy in ocular diseases: from mechanisms to therapeutic potential  Frontiers

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways - Frontiers

Plant secondary metabolites exert therapeutic effects by modulating autophagy pathways  Frontiers

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development - Frontiers

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development  Frontiers

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...

Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press

The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Historical landmarks of autophagy research - Nature

Historical landmarks of autophagy research  Nature

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration...

SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration  Nature

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Impact of context-dependent autophagy states on tumor progression - Nature

Impact of context-dependent autophagy states on tumor progression  Nature

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center

The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Autophagy: molecular machinery for self-eating - Nature

Autophagy: molecular machinery for self-eating  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Upregulated pexophagy limits the capacity of selective autophagy - Nature

Upregulated pexophagy limits the capacity of selective autophagy  Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension...

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension  American Heart Association Journals

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

On the caveats of AI autophagy - Nature

On the caveats of AI autophagy  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS

Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy - Nature

A mechanism that ensures non-selective cytoplasm degradation by autophagy  Nature

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Autophagy as a promoter of longevity: insights from model organisms - Nature

Autophagy as a promoter of longevity: insights from model organisms  Nature

Activating Autophagy to Prevent Doxorubicin Cardiomyopathy: The Timing Matters - American Heart A...

Activating Autophagy to Prevent Doxorubicin Cardiomyopathy: The Timing Matters  American Heart Association Journals

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Biological Functions of Autophagy Genes: A Disease Perspective - ScienceDirect.com

Biological Functions of Autophagy Genes: A Disease Perspective  ScienceDirect.com

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing - Nature

Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing  Nature

Cellular quality control by the ubiquitin-proteasome system and autophagy - Science | AAAS

Cellular quality control by the ubiquitin-proteasome system and autophagy  Science | AAAS

Autophagy regulation by RNA alternative splicing and implications in human diseases - Nature

Autophagy regulation by RNA alternative splicing and implications in human diseases  Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise - Nature

Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise  Nature

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS

Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Autophagy in Cardiovascular Aging | Circulation Research - American Heart Association Journals

Autophagy in Cardiovascular Aging | Circulation Research  American Heart Association Journals

Autophagy mediates an amplification loop during ferroptosis - Nature

Autophagy mediates an amplification loop during ferroptosis  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai

Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature

Autophagy promotes jasmonate-mediated defense against nematodes  Nature

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals ...

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals  Nature

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy - Nature

Plekhg5 controls the unconventional secretion of Sod1 by presynaptic secretory autophagy  Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press

Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy - Science | AAAS

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy  Science | AAAS

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

NBR1: The archetypal selective autophagy receptor - Rockefeller University Press

NBR1: The archetypal selective autophagy receptor  Rockefeller University Press

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ...

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress  Nature

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-dri...

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers  Nature

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway - Nature

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway  Nature