First-Ever Human Trial Finds Fasting Mimicking Diet Enhances Autophagy While Improving Metabolic ...

First-Ever Human Trial Finds Fasting Mimicking Diet Enhances Autophagy While Improving Metabolic Health | Newswise  Newswise

Development of a p62 biodegrader for autophagy targeted degradation - Nature

Development of a p62 biodegrader for autophagy targeted degradation  Nature

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan - PNAS

Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan  PNAS

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

The Japan autophagy consortium - Nature

The Japan autophagy consortium  Nature

V-ATPase-dependent induction of selective autophagy - Nature

V-ATPase-dependent induction of selective autophagy  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling...

Autophagy acts as a brake on obesity-related fibrosis by controlling purine nucleoside signalling  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autoph...

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy  Nature

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature

WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression - Na...

Phase separation promotes Atg8 lipidation and vesicle condensation for autophagy progression  Nature

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticle...

Evaluating cell cycle- and autophagy-associated cellular accumulation of lipid-based nanoparticles  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature

Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in respon...

Autophagy controls differentiation of Drosophila blood cells by regulating Notch levels in response to nutrient availability  Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation - Nature

Defective autophagy in CD4 T cells drives liver fibrosis via type 3 inflammation  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITC...

Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH  Nature

p97/VCP is required for piecemeal autophagy of aggresomes - Nature

p97/VCP is required for piecemeal autophagy of aggresomes  Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis - Nature

Reciprocal stabilization of CtBP and TRIM28 represses autophagy to promote metastasis  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β...

Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia  Nature

The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis - Nature

The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis  Nature

Novel peptides from the edible bivalve Ruditapes decussatus target apoptosis, autophagy, and FGF1...

Novel peptides from the edible bivalve Ruditapes decussatus target apoptosis, autophagy, and FGF19-FGFR4 signaling in human cancer cell lines  Nature

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under ther...

Chaperone-mediated autophagy manipulates PGC1α stability and governs energy metabolism under thermal stress  Nature

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet...

Endolysosomal processing of neuron-derived signaling lipids regulates autophagy and lipid droplet degradation in astrocytes  Nature

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention - Front...

Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention  Frontiers

Disulfiram Boosts Autophagy, Enhances Chloroquine Synergy - Bioengineer.org

Disulfiram Boosts Autophagy, Enhances Chloroquine Synergy  Bioengineer.org

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axi...

Sinularin induces autophagy-dependent cell death by activating ULK1 and enhancing FOXO3-ATG4A axis in prostate cancer cells  Nature

SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac ...

SLC26A4 regulates autophagy and activates the NLRP3 inflammasome to mediate pathological cardiac hypertrophy  Nature

Rab GTPases are evolutionarily conserved signals mediating selective autophagy - Rockefeller Univ...

Rab GTPases are evolutionarily conserved signals mediating selective autophagy  Rockefeller University Press

Sex and region-specific disruption of autophagy and mitophagy in Alzheimer’s disease: linking cel...

Sex and region-specific disruption of autophagy and mitophagy in Alzheimer’s disease: linking cellular dysfunction to cognitive decline  Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries - Nature

Recruitment of Atg1 to the phagophore by Atg8 orchestrates autophagy machineries  Nature

Autophagy and extracellular vesicles mediate cisplatin resistance in oral squamous cell carcinoma...

Autophagy and extracellular vesicles mediate cisplatin resistance in oral squamous cell carcinoma with LC3B-II as a potential non-invasive biomarker  Nature

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis - ...

Autophagy-related biomarkers identified in sepsis-induced ARDS through bioinformatics analysis  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature

Autophagy is induced during plant grafting to promote wound healing  Nature

JNCASR Finds Exocyst Complex Drives Autophagy, Opening New Therapeutic Pathways - Devdiscourse

JNCASR Finds Exocyst Complex Drives Autophagy, Opening New Therapeutic Pathways  Devdiscourse

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue - Wiley

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue  Wiley

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS

Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS

STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

ERS regulates endometrial epithelial cell autophagy through XBP1s -mediated activation of the PI3...

ERS regulates endometrial epithelial cell autophagy through XBP1s -mediated activation of the PI3K/AKT pathway  Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity - Nature

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity  Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3 - Nature

PTBP2 promotes cell survival and autophagy in chronic myeloid leukemia by stabilizing BNIP3  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy | Cell Death Discovery -...

Loss of TC-PTP in keratinocytes leads to increased UVB-induced autophagy | Cell Death Discovery  Nature

Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombo...

Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombosis  Nature

Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology - Nature

Autophagy repression in effector T lymphocytes redefines paradigms in T cell biology  Nature

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience - Nature

Restoring the primary cilia–autophagy axis in neurons to foster cognitive resilience  Nature

RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical canc...

RAB33A promotes metastasis via RhoC accumulation through non-canonical autophagy in cervical cancer  Nature

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity - ...

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity  Nature

ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation - Nature

ADSL promotes autophagy and tumor growth through fumarate-mediated Beclin1 dimethylation  Nature

On the caveats of AI autophagy - Nature

On the caveats of AI autophagy  Nature

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outsi...

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling  Nature

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during...

Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging  Nature

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like prot...

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope  Nature

Shiseido discovers new features in Alternative autophagy through joint research with The Institut...

Shiseido discovers new features in Alternative autophagy through joint research with The Institute of Science Tokyo  資生堂 企業情報

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature

Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy  Nature

Chemically engineered antibodies for autophagy-based receptor degradation - Nature

Chemically engineered antibodies for autophagy-based receptor degradation  Nature

ATG8 delipidation is not universally critical for autophagy in plants - Nature

ATG8 delipidation is not universally critical for autophagy in plants  Nature

Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating...

Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway  Nature

Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress - Nature

Stress granules sequester autophagy proteins to facilitate plant recovery from heat stress  Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy - Nature

Polphylipoprotein-induced autophagy mechanism with high performance in photodynamic therapy  Nature

Historical landmarks of autophagy research - Cell Research - Nature

Historical landmarks of autophagy research - Cell Research  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature

Circadian autophagy drives iTRF-mediated longevity  Nature

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in p...

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer  Nature

BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stre...

BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration  Nature

AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treatin...

AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields) | Cell Death & Disease  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melan...

Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

Hypoxia-induced autophagy in pancreatic cancer counteracts the cytotoxicity of CD8 - Nature

Hypoxia-induced autophagy in pancreatic cancer counteracts the cytotoxicity of CD8  Nature

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells b...

PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature

Spermidine is essential for fasting-mediated autophagy and longevity  Nature

Autophagy and Stem Cells: Self-Eating for Self-Renewal - Frontiers

Autophagy and Stem Cells: Self-Eating for Self-Renewal  Frontiers

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Autophagy: Regulator of cell death - Cell Death & Disease - Nature

Autophagy: Regulator of cell death - Cell Death & Disease  Nature

Nonlytic viral spread enhanced by autophagy components - PNAS

Nonlytic viral spread enhanced by autophagy components  PNAS

Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colore...

Tumor-intrinsic expression of the autophagy gene Atg16l1 suppresses anti-tumor immunity in colorectal cancer  Nature

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers

Interplay Between NLRP3 Inflammasome and Autophagy  Frontiers

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential act...

Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts  Nature

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease mode...

Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Amantadine against glioma via ROS-mediated apoptosis and autophagy arrest - Nature

Amantadine against glioma via ROS-mediated apoptosis and autophagy arrest  Nature

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms throug...

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking | Communications Biology  Nature

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia - Nature

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia  Nature

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal ...

Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes  Nature

Autophagy-dependent survival is controlled with a unique regulatory network upon various cellular...

Autophagy-dependent survival is controlled with a unique regulatory network upon various cellular stress events  Nature