"オートファジー" の関連情報検索結果

Autophagy modulation in cancer - Nature



Autophagy modulation in cancer  Nature

Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives - Frontiers



Autophagy: mechanisms, roles in human diseases, and therapeutic perspectives  Frontiers

A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking - Rockefeller Un...



A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking  Rockefeller University Press

Chemical compound clears cellular waste, protects neurons in model of frontotemporal dementia - W...



Chemical compound clears cellular waste, protects neurons in model of frontotemporal dementia  WashU Medicine

Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activatio...



Defective autophagy in GNE myopathy is rescued by inhibition of noncanonical Akt–mTORC1 activation across multiple isogenic models  Nature

Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases - Frontiers



Autophagy, NET formation, and inflammation crosstalk in thrombotic autoimmune diseases  Frontiers

Translation in proximity to forming autophagosomes during sustained autophagy - Nature



Translation in proximity to forming autophagosomes during sustained autophagy  Nature

Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development - Frontiers



Autophagy-phytohormone crosstalk: a dual-regulation axis in plant development  Frontiers

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a ...



A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia  Nature

Core principles of autophagy initiation mechanisms - Nature



Core principles of autophagy initiation mechanisms  Nature

Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeut...



Ubiquitination and autophagy in host–pathogen interactions: from immune surveillance to therapeutic targeting  Nature

Autophagy-regulated mitochondrial inheritance controls early CD8 - Nature



Autophagy-regulated mitochondrial inheritance controls early CD8  Nature

A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers - Nature



A nile red fluorescence assay for LC3 autophagy protein binding to lipid bilayers  Nature

Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restore...



Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity  Nature

Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopa...



Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy  Nature

Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in ...



Hemp seed extract exerts cytostatic effects through metabolic stress and autophagy modulation in malignant cells  Nature

Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protec...



Herbal terpenoids activate autophagy and mitophagy through modulation of bioenergetics and protect from metabolic stress, sarcopenia and epigenetic aging  Nature

Development of a p62 biodegrader for autophagy targeted degradation - Nature



Development of a p62 biodegrader for autophagy targeted degradation  Nature

Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synap...



Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome  Nature

Emerging perspectives on the selective autophagy of melanosomes: melanophagy - Nature



Emerging perspectives on the selective autophagy of melanosomes: melanophagy  Nature

Identification of organelle-specific autophagy regulators from tandem CRISPR screens - Rockefelle...



Identification of organelle-specific autophagy regulators from tandem CRISPR screens  Rockefeller University Press

Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophag...



Reconstitution of BNIP3/NIX-mitophagy initiation reveals hierarchical flexibility of the autophagy machinery  Nature

The rapidly expanding role of LC3-interacting regions in autophagy - Rockefeller University Press



The rapidly expanding role of LC3-interacting regions in autophagy  Rockefeller University Press

Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stoma...



Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening  PNAS

Historical landmarks of autophagy research - Nature



Historical landmarks of autophagy research  Nature

UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits - Universi...



UGM Expert Says Ramadan Fasting Triggers Autophagy and Offers Multiple Health Benefits  Universitas Gadjah Mada

WSTF nuclear autophagy regulates chronic but not acute inflammation - Nature



WSTF nuclear autophagy regulates chronic but not acute inflammation  Nature

Spermidine is essential for fasting-mediated autophagy and longevity - Nature



Spermidine is essential for fasting-mediated autophagy and longevity  Nature

MYTHO is a novel regulator of skeletal muscle autophagy and integrity - Nature



MYTHO is a novel regulator of skeletal muscle autophagy and integrity  Nature

Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder ...



Autophagy dysregulation via the USP20-ULK1 axis in the HERC2-related neurodevelopmental disorder  Nature

TRIM23 mediates cGAS-induced autophagy in anti-HSV defense - Nature



TRIM23 mediates cGAS-induced autophagy in anti-HSV defense  Nature

C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer - Nature



C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer  Nature

Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy an...



Unconventional secretion of PARK7 requires lysosomal delivery via chaperone-mediated autophagy and specialized SNARE complex  PNAS

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machin...



Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells  Nature

Autophagy: molecular machinery for self-eating - Nature



Autophagy: molecular machinery for self-eating  Nature

Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression - Nature



Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression  Nature

ApoE4 attenuates autophagy via FoxO3a repression in the brain - Nature



ApoE4 attenuates autophagy via FoxO3a repression in the brain  Nature

Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokal...



Atg7 -dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia  Nature

Impact of context-dependent autophagy states on tumor progression - Nature



Impact of context-dependent autophagy states on tumor progression  Nature

Structural pathway for PI3-kinase regulation by VPS15 in autophagy - Science | AAAS



Structural pathway for PI3-kinase regulation by VPS15 in autophagy  Science | AAAS

The Beth Levine, M.D. Prize in Autophagy Research - UT Southwestern Medical Center



The Beth Levine, M.D. Prize in Autophagy Research  UT Southwestern Medical Center

Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and au...



Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways  Nature

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy - Nature



Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy  Nature

Enhancing autophagy by redox regulation extends lifespan in Drosophila - Nature



Enhancing autophagy by redox regulation extends lifespan in Drosophila  Nature

Stress dynamically modulates neuronal autophagy to gate depression onset - Nature



Stress dynamically modulates neuronal autophagy to gate depression onset  Nature

Circadian autophagy drives iTRF-mediated longevity - Nature



Circadian autophagy drives iTRF-mediated longevity  Nature

Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentia...



Spermidine induces autophagy by inhibiting the acetyltransferase EP300 | Cell Death & Differentiation  Nature

Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arab...



Autophagy maintains endosperm quality during seed storage to preserve germination ability in Arabidopsis  PNAS

Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atheroscler...



Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis  American Heart Association Journals

The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension...



The Novel Lysosomal Autophagy Inhibitor (ROC-325) Ameliorates Experimental Pulmonary Hypertension  American Heart Association Journals

Upregulated pexophagy limits the capacity of selective autophagy - Nature



Upregulated pexophagy limits the capacity of selective autophagy  Nature

Interplay Between NLRP3 Inflammasome and Autophagy - Frontiers



Interplay Between NLRP3 Inflammasome and Autophagy  Frontiers

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I - Nature



Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I  Nature

Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mec...



Many roads lead to CASM: Diverse stimuli of noncanonical autophagy share a unifying molecular mechanism  Science | AAAS

Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive ...



Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder?  Nature

Autophagy Special Collection: Cell machinery dealing with stress and beyond - Science | AAAS



Autophagy Special Collection: Cell machinery dealing with stress and beyond  Science | AAAS

USF2 and TFEB compete in regulating lysosomal and autophagy genes - Nature



USF2 and TFEB compete in regulating lysosomal and autophagy genes  Nature

A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilien...



A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience  Nature

Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection - PNAS



Autophagy-mediated downregulation of AXL and TIM-1 promotes sustained Zika virus infection  PNAS

Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Musc...



Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p  American Heart Association Journals

Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regress...



Age-Related Impairments in Immune Cell Efferocytosis and Autophagy Hinder Atherosclerosis Regression  American Heart Association Journals

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pul...



Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension  American Heart Association Journals

Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse...



Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders  Nature

TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of...



TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway  Nature

Autophagy is induced during plant grafting to promote wound healing - Nature



Autophagy is induced during plant grafting to promote wound healing  Nature

Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabol...



Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism  Science | AAAS

p97/VCP is required for piecemeal autophagy of aggresomes - Nature



p97/VCP is required for piecemeal autophagy of aggresomes  Nature

On the caveats of AI autophagy - Nature



On the caveats of AI autophagy  Nature

Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4K...



Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis  Nature

Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis - Nature



Loss of WIPI4 in neurodegeneration causes autophagy-independent ferroptosis  Nature

Autophagy promotes jasmonate-mediated defense against nematodes - Nature



Autophagy promotes jasmonate-mediated defense against nematodes  Nature

Autophagy in Atherosclerosis: Not All Foam Cells Are Created Equal - American Heart Association J...



Autophagy in Atherosclerosis: Not All Foam Cells Are Created Equal  American Heart Association Journals

Autophagy as a promoter of longevity: insights from model organisms - Nature



Autophagy as a promoter of longevity: insights from model organisms  Nature

Autophagy regulation by RNA alternative splicing and implications in human diseases - Nature



Autophagy regulation by RNA alternative splicing and implications in human diseases  Nature

Autophagy: Recycling Is Good for Your Body Too - Cedars-Sinai



Autophagy: Recycling Is Good for Your Body Too  Cedars-Sinai

Autophagy mediates an amplification loop during ferroptosis - Nature



Autophagy mediates an amplification loop during ferroptosis  Nature

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer - Nature



Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer  Nature

Beyond autophagy: LC3-associated phagocytosis and endocytosis - Science | AAAS



Beyond autophagy: LC3-associated phagocytosis and endocytosis  Science | AAAS

Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex - Nature



Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex  Nature

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence - Nature



Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence  Nature

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals ...



SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals  Nature

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans - The New England Journ...



Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans  The New England Journal of Medicine

Autophagy in mammalian development and differentiation - Nature



Autophagy in mammalian development and differentiation  Nature

Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern...



Andrea Ballabio, M.D., awarded Beth Levine, M.D. Prize in Autophagy Research from UT Southwestern: Newsroom  UT Southwestern Medical Center

Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila ...



Identification of new candidates regulating autophagy-dependent midgut degradation in Drosophila melanogaster  Nature

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy - Science | AAAS



Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy  Science | AAAS

Rab GTPases as “eat me” signals for selective autophagy - Rockefeller University Press



Rab GTPases as “eat me” signals for selective autophagy  Rockefeller University Press

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-dri...



Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers  Nature

TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ...



TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress  Nature

Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research - Nature



Degradation of lipid droplets by chimeric autophagy-tethering compounds - Cell Research  Nature

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway - Nature



Autophagy induction via STING trafficking is a primordial function of the cGAS pathway  Nature

Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of ...



Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11  PNAS

Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms - American He...



Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms  American Heart Association Journals

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depress...



Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice  Nature

Autophagy in Human Diseases - The New England Journal of Medicine



Autophagy in Human Diseases  The New England Journal of Medicine

Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI co...



Integrated proteomics reveals autophagy landscape and an autophagy receptor controlling PKA-RI complex homeostasis in neurons  Nature

STING-induced noncanonical autophagy regulates endolysosomal homeostasis - PNAS



STING-induced noncanonical autophagy regulates endolysosomal homeostasis  PNAS

Mechanism and medical implications of mammalian autophagy - Nature



Mechanism and medical implications of mammalian autophagy  Nature

Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion - Nature



Autophagy-independent role of ATG9A vesicles as carriers for galectin-9 secretion  Nature

Chemically engineered antibodies for autophagy-based receptor degradation - Nature



Chemically engineered antibodies for autophagy-based receptor degradation  Nature