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HCV Replicon Systems: Workhorses of Drug Discovery and Resistance - Frontiers



HCV Replicon Systems: Workhorses of Drug Discovery and Resistance  Frontiers

Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protect...



Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets  Nature

Engineering a Sinorhizobium meliloti Chassis with Monopartite, Single Replicon Genome Configurati...



Engineering a Sinorhizobium meliloti Chassis with Monopartite, Single Replicon Genome Configuration  ACS Publications

Experts move to allay replicon COVID shot fears in Japan amid backlash - The Japan Times



Experts move to allay replicon COVID shot fears in Japan amid backlash  The Japan Times

Fig. 1 | Single-cell measurements of VEEV replicon RNA amplification in... - ResearchGate



Fig. 1 | Single-cell measurements of VEEV replicon RNA amplification in...  ResearchGate

Japanese doctors oppose new coronavirus vaccine: ‘Replicon vaccine’ - arabnews.jp



Japanese doctors oppose new coronavirus vaccine: ‘Replicon vaccine’  arabnews.jp

Packaging of alphavirus-based self-amplifying mRNA yields replication-competent virus through a m...



Packaging of alphavirus-based self-amplifying mRNA yields replication-competent virus through a mechanism of aberrant homologous RNA recombination  ASM Journals

Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated contr...



Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus | npj Vaccines  Nature

An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell re...



An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates  Science | AAAS

Replicon-seq - Memorial Sloan Kettering Cancer Center



Replicon-seq  Memorial Sloan Kettering Cancer Center

Schematic representation of enveloped RNA viruses’ genome and... - ResearchGate



Schematic representation of enveloped RNA viruses’ genome and...  ResearchGate

Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a pro...



Cell type dependent stability and virulence of a recombinant SARS-CoV-2, and engineering of a propagation deficient RNA replicon to analyze virus RNA synthesis  Frontiers

Design of Novel Synthetic RNA Replicons Based on Emesvirus zinderi - ACS Publications



Design of Novel Synthetic RNA Replicons Based on Emesvirus zinderi  ACS Publications

Recapitulation of the Powassan virus life cycle in cell culture - ASM Journals



Recapitulation of the Powassan virus life cycle in cell culture  ASM Journals

Table 2 . Inc/replicon types of conjugative plasmids carrying... - ResearchGate



Table 2 . Inc/replicon types of conjugative plasmids carrying...  ResearchGate

A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation - Scientific Reports - Nature



A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation - Scientific Reports  Nature

In-planta Gene Targeting in Barley Using Cas9 With and Without Geminiviral Replicons - Frontiers



In-planta Gene Targeting in Barley Using Cas9 With and Without Geminiviral Replicons  Frontiers

An RNA replicon system to investigate promising inhibitors of feline coronavirus - ASM Journals



An RNA replicon system to investigate promising inhibitors of feline coronavirus  ASM Journals

Reconstitution of a telomeric replicon organized by CST - Nature



Reconstitution of a telomeric replicon organized by CST  Nature

Replicon-Based Typing of IncI-Complex Plasmids, and Comparative Genomics Analysis of IncIγ/K1 Pla...



Replicon-Based Typing of IncI-Complex Plasmids, and Comparative Genomics Analysis of IncIγ/K1 Plasmids  Frontiers

Multiple-Replicon Resistance Plasmids of Klebsiella Mediate Extensive Dissemination of Antimicrob...



Multiple-Replicon Resistance Plasmids of Klebsiella Mediate Extensive Dissemination of Antimicrobial Genes  Frontiers

West Nile virus infectious replicon particles generated using a packaging-restricted cell line is...



West Nile virus infectious replicon particles generated using a packaging-restricted cell line is a safe reporter system  Nature

Alphavirus Replicon DNA Vectors Expressing Ebola GP and VP40 Antigens Induce Humoral and Cellular...



Alphavirus Replicon DNA Vectors Expressing Ebola GP and VP40 Antigens Induce Humoral and Cellular Immune Responses in Mice  Frontiers

A pathogenicity island replicon in Staphylococcus aureus replicates as an unstable plasmid - PNAS



A pathogenicity island replicon in Staphylococcus aureus replicates as an unstable plasmid  PNAS

Construction of a Noninfectious SARS-CoV-2 Replicon for Antiviral-Drug Testing and Gene Function ...



Construction of a Noninfectious SARS-CoV-2 Replicon for Antiviral-Drug Testing and Gene Function Studies  ASM Journals

Bivalent hemagglutinin and neuraminidase influenza replicon particle vaccines protect pigs agains...



Bivalent hemagglutinin and neuraminidase influenza replicon particle vaccines protect pigs against influenza a virus without causing vaccine associated enhanced respiratory disease  ScienceDirect.com

Plasmid Replicon Typing of Antibiotic-Resistant Escherichia coli From Clams and Marine Sediments ...



Plasmid Replicon Typing of Antibiotic-Resistant Escherichia coli From Clams and Marine Sediments  Frontiers

Establishment of a Replicon Reporter of the Emerging Tick-Borne Bourbon Virus and Use It for Eval...



Establishment of a Replicon Reporter of the Emerging Tick-Borne Bourbon Virus and Use It for Evaluation of Antivirals  Frontiers

Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNA...



Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs  PNAS

AI-powered Scheduling And Automated Labor Compliance With Replicon Workforce Management Solution ...



AI-powered Scheduling And Automated Labor Compliance With Replicon Workforce Management Solution  PR Newswire

Deltek Closes Replicon Acquisition; Mike Corkery Quoted - GovCon Wire



Deltek Closes Replicon Acquisition; Mike Corkery Quoted  GovCon Wire

A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon p...



A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles  Nature

Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DN...



Increased Immunogenicity of a DNA-Launched Venezuelan Equine Encephalitis Virus-Based Replicon DNA Vaccine  ASM Journals

Stable Expression of a Hepatitis E Virus (HEV) RNA Replicon in Two Mammalian Cell Lines to Assess...



Stable Expression of a Hepatitis E Virus (HEV) RNA Replicon in Two Mammalian Cell Lines to Assess Mechanism of Innate Immunity and Antiviral Response  Frontiers

DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice | Scien...



DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice | Scientific Reports  Nature

An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent imm...



An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant  Nature

Replicon Announces Polaris PSA 2022 Spring Release: Reinvigorating The World's First Self-driving...



Replicon Announces Polaris PSA 2022 Spring Release: Reinvigorating The World's First Self-driving PSA, Ushering in The Third Wave of Resource Management  PR Newswire

Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin ...



Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin Promote Humoral and Cellular Immune Responses in Pigs  Frontiers

A Tomato Spotted Wilt Virus S RNA-based Replicon System in Yeast - Nature



A Tomato Spotted Wilt Virus S RNA-based Replicon System in Yeast  Nature

Construction of a Severe Acute Respiratory Syndrome Coronavirus Infectious cDNA Clone and a Repli...



Construction of a Severe Acute Respiratory Syndrome Coronavirus Infectious cDNA Clone and a Replicon To Study Coronavirus RNA Synthesis  ASM Journals

Highly efficient homology‐directed repair using CRISPR/Cpf1‐geminiviral replicon in tomato - Wile...



Highly efficient homology‐directed repair using CRISPR/Cpf1‐geminiviral replicon in tomato  Wiley Online Library

A temperature-regulated replicon-based DNA expression system - Nature



A temperature-regulated replicon-based DNA expression system  Nature

In vitro evolution of enhanced RNA replicons for immunotherapy - Nature



In vitro evolution of enhanced RNA replicons for immunotherapy  Nature

Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon - Frontiers



Clostridium autoethanogenum isopropanol production via native plasmid pCA replicon  Frontiers

Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus gl...



Alphavirus vector-based replicon particles expressing multivalent cross-protective Lassa virus glycoproteins  ScienceDirect.com

SMC condensin: promoting cohesion of replicon arms - Nature



SMC condensin: promoting cohesion of replicon arms  Nature

Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced i...



Virus replicon particle vaccines expressing nucleoprotein of influenza A virus mediate enhanced inflammatory responses in pigs  Nature

Replicon Announces Time Intelligence Platform for Cloud-based Solutions from SAP for the Professi...



Replicon Announces Time Intelligence Platform for Cloud-based Solutions from SAP for the Professional Services Industry  PR Newswire

Golden Gate Cloning-Compatible DNA Replicon/2A-Mediated Polycistronic Vectors for Plants - Frontiers



Golden Gate Cloning-Compatible DNA Replicon/2A-Mediated Polycistronic Vectors for Plants  Frontiers

Deltek has acquired Replicon to clock in for project success - ERP Today



Deltek has acquired Replicon to clock in for project success  ERP Today

Replicon typing of plasmids carrying blaCTX-M-1 in Enterobacteriaceae of animal, environmental an...



Replicon typing of plasmids carrying blaCTX-M-1 in Enterobacteriaceae of animal, environmental and human origin  Frontiers

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines - News-Medical



Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines  News-Medical

An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell re...



An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates  Science | AAAS

An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for v...



An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis  PNAS

DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be fur...



DNA-launched RNA replicon vaccines induce potent anti-Ebolavirus immune responses that can be further improved by a recombinant MVA boost  Nature

Reverse Genetic Approaches for the Generation of Full Length and Subgenomic Replicon of EV71 Viru...



Reverse Genetic Approaches for the Generation of Full Length and Subgenomic Replicon of EV71 Virus  Frontiers

Facile method for delivering chikungunya viral replicons into mosquitoes and mammalian cells - Na...



Facile method for delivering chikungunya viral replicons into mosquitoes and mammalian cells  Nature

Deltek Reaches Agreement to Acquire Replicon, A Global Provider of Knowledge Workforce Management...



Deltek Reaches Agreement to Acquire Replicon, A Global Provider of Knowledge Workforce Management Solutions for Project and Service-Centric Organizations  PR Newswire

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective imm...



An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats  Nature

Replicon Named to Inc.'s Second Annual Power Partner Awards - PR Newswire



Replicon Named to Inc.'s Second Annual Power Partner Awards  PR Newswire

Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing - ...



Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing  PNAS

Replication and single-cycle delivery of SARS-CoV-2 replicons - Science | AAAS



Replication and single-cycle delivery of SARS-CoV-2 replicons  Science | AAAS

Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates - News-Medical



Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates  News-Medical

New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture system...



New research on nirmatrelvir resistance in SARS-CoV-2 using powerful replicon cell culture systems  News-Medical

Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthe...



Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors | mBio  ASM Journals

A Minimal Replicon Enables Efficacious, Species-Specific Gene Deletion in Chlamydia and Extension...



A Minimal Replicon Enables Efficacious, Species-Specific Gene Deletion in Chlamydia and Extension of Gene Knockout Studies to the Animal Model of Infection Using Chlamydia muridarum  ASM Journals

Cloning and characterization of the Inc A/C plasmid RA1 replicon - ASM Journals



Cloning and characterization of the Inc A/C plasmid RA1 replicon  ASM Journals

A Single Dose SARS-CoV-2 Replicon RNA Vaccine Induces Cellular and Humoral Immune Responses in Si...



A Single Dose SARS-CoV-2 Replicon RNA Vaccine Induces Cellular and Humoral Immune Responses in Simian Immunodeficiency Virus Infected and Uninfected Pigtail Macaques  Frontiers

Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replico...



Middle East respiratory syndrome coronavirus vaccine based on a propagation-defective RNA replicon elicited sterilizing immunity in mice  PNAS

Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenom...



Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons  ASM Journals

Employee time-tracking startup Replicon acquired by US-based Deltek - BetaKit



Employee time-tracking startup Replicon acquired by US-based Deltek  BetaKit

High-throughput neutralization assay for multiple flaviviruses based on single-round infectious p...



High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon  Nature

Time Tracking for Service Organizations from Replicon Now an SAP® Endorsed App and Part of SAP's ...



Time Tracking for Service Organizations from Replicon Now an SAP® Endorsed App and Part of SAP's Industry Cloud  PR Newswire

Identification of the minimal replicon and the origin of replication of the crenarchaeal plasmid ...



Identification of the minimal replicon and the origin of replication of the crenarchaeal plasmid pRN1  Wiley Online Library

Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthe...



Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors  ASM Journals

Alphavirus Replicon Particle Vaccine Breaks B Cell Tolerance and Rapidly Induces IgG to Murine He...



Alphavirus Replicon Particle Vaccine Breaks B Cell Tolerance and Rapidly Induces IgG to Murine Hematolymphoid Tumor Associated Antigens  Frontiers

Synthetic Genomics Announces Collaboration with Johnson & Johnson Innovation to Develop Novel The...



Synthetic Genomics Announces Collaboration with Johnson & Johnson Innovation to Develop Novel Therapeutics Using Synthetic Genomics' Replicon RNA Technology  PR Newswire

A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccin...



A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccine  Frontiers

HCV genome organization and direct-acting antivirals for the treatment... - ResearchGate



HCV genome organization and direct-acting antivirals for the treatment...  ResearchGate

Deltek completes acquisition of Replicon - Consultancy.uk



Deltek completes acquisition of Replicon  Consultancy.uk

Construction and characterization of two SARS‐CoV‐2 minigenome replicon systems - Wiley Online Li...



Construction and characterization of two SARS‐CoV‐2 minigenome replicon systems  Wiley Online Library

Fig. 2. Removal of input replicon RNA by 5-EU labelling and RNA... - ResearchGate



Fig. 2. Removal of input replicon RNA by 5-EU labelling and RNA...  ResearchGate

Rise of the RNA machines: Self-amplification in mRNA vaccine design - Phys.org



Rise of the RNA machines: Self-amplification in mRNA vaccine design  Phys.org

Opinion: Unleashing Self-replicating Vaccines Upon the World - Dallas Express



Opinion: Unleashing Self-replicating Vaccines Upon the World  Dallas Express

Replicon: a software to accurately predict DNA replication timing in metazoan cells - Frontiers



Replicon: a software to accurately predict DNA replication timing in metazoan cells  Frontiers

Development and preclinical evaluation of an alphavirus replicon vaccine for influenza - ScienceD...



Development and preclinical evaluation of an alphavirus replicon vaccine for influenza  ScienceDirect.com

Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility - ...



Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility  PNAS

Deltek expands time tracking solutions with Replicon deal - Consultancy.com.au



Deltek expands time tracking solutions with Replicon deal  Consultancy.com.au

Fig. 1. Construction and transcriptional analysis of SARS-CoV-2... - ResearchGate



Fig. 1. Construction and transcriptional analysis of SARS-CoV-2...  ResearchGate

Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial vir...



Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates  ScienceDirect.com

Development of a novel adenovirus–alphavirus hybrid vector with RNA replicon features for maligna...



Development of a novel adenovirus–alphavirus hybrid vector with RNA replicon features for malignant hematopoietic cell transduction  Nature

–A Natural Replicon with Functional RepABC Modules from Rhodobacteraceae and Rhizobiaceae - Front...



–A Natural Replicon with Functional RepABC Modules from Rhodobacteraceae and Rhizobiaceae  Frontiers

Interference of hepatitis C virus RNA replication by short interfering RNAs - PNAS



Interference of hepatitis C virus RNA replication by short interfering RNAs  PNAS

Enhancement of protein expression by alphavirus replicons by designing self-replicating subgenomi...



Enhancement of protein expression by alphavirus replicons by designing self-replicating subgenomic RNAs  PNAS

Alphavirus replicon vaccines | Animal Health Research Reviews - Cambridge University Press & Asse...



Alphavirus replicon vaccines | Animal Health Research Reviews  Cambridge University Press & Assessment

Deltek to acquire Calgary-based enterprise software firm Replicon - Consulting.ca



Deltek to acquire Calgary-based enterprise software firm Replicon  Consulting.ca

Figure 3. Main features of the plasmid pWV01 replicon. The repA and... - ResearchGate



Figure 3. Main features of the plasmid pWV01 replicon. The repA and...  ResearchGate

Transfection-independent production of alphavirus replicon particles based on poxvirus expression...



Transfection-independent production of alphavirus replicon particles based on poxvirus expression vectors  Nature

Figure 4. Plasmid replicon screening. PlasmidFinder was used to screen... - ResearchGate



Figure 4. Plasmid replicon screening. PlasmidFinder was used to screen...  ResearchGate

Figure 6 A. Stress resistance, virulence and plasmid replicon gene... - ResearchGate



Figure 6 A. Stress resistance, virulence and plasmid replicon gene...  ResearchGate